Researchers from the Kanchanawong Lab at the Mechanobiology Institute, NUS makes cutting-edge 3D nanoscopy more accessible to researchers without elaborate optical engineering.
Researchers from the Kanchanawong Lab at the Mechanobiology Institute, NUS discover a marker of ground-state pluripotent stem cells and what governs it.
A research team led by Mechanobiology Institute (MBI) Principal Investigators Assoc. Prof. Tony Kanchanawong and Prof. Rong Li was recently awarded a Ministry of Education Academic Research Fund (MOE AcRF) Tier 3 grant.
Recent study led by MBI graduate student Shumin Xia and Principal Investigator Associate Professor Pakorn Tony Kanchanawong use super resolution imaging techniques to study the nanoscale organization of the cortical actin cytoskeleton in mouse embryonic stem cells and understand the role of molecules such as Arp2/3, formins, and capping protein in coordinating cortical architecture in mESCs.
Focal adhesions in embryonic stem cells
Actin remodeling drives bile regurgitation during obstructive cholestasis
Using superresolution imagining to map adherens junction machinery
Reverse engineering molecular machines
Visualizing the building blocks of cell-cell adhesion
A leading global university centred in Asia, NUS is Singapore's flagship university, offering a global approach to education and research with a focus on Asian perspectives and expertise.
One of four Research Centres of Excellence at NUS, MBI is working to identify, measure and describe how the forces for motility and morphogenesis are expressed at the molecular, cellular and tissue level.