MBI Laboratories

MBI’s core labs cover protein expression, microscopy, computation, nanofabrication, cell culture and other essential services to better serve the Institute members.

New tools exist to measure the position of cellular components at the nanometer (molecular) level as well as their dynamics and to measure and apply forces to single molecules in sub-cellular regions. When coupled with the explosion of knowledge in computational biology and modeling, it is now possible to address major unanswered questions of exactly how cells and tissues move, sense environmental forces and apply forces to neighboring cells or matrices.

Our core facilities cover protein expression, microscopy, computation, nanofabrication, cell culture and other essential services to better serve the Institute members. We provide equipment, staff and service to support and overcome the experimental and computational challenges that our principal investigators, researchers and students may face.

The MBI laboratories facilitate image-related research and offer a wide range of microscopes and image analysis resources. Our expert staff ensure the smooth and reliable operation of our facilities and labs. MBI’s open lab concept demonstrates a modern concept for scientific collaboration and research. Laboratory manager, LIANG Mui Yee, Rosa Cynthia is available to answer your questions about MBI’s laboratory resources.

(L to R) Lim Beng Meng, Christine, Mohamed Yusaini Bin Mohamed Sani, Tan Bee Leng, Wong Kwan Pooi, June, Sellam Kannan, Liang Mui Yee, Rosa Cynthia, Ong Tien Yin, Moshi, Tan Song Hui, Juliana Binte Jumahat, Tan Chye Heng.

Laboratory Design and Concept

The Mechanobiology Institute laboratories design is based on the bold, unconventional concept of an ‘open laboratory’. There are no walls or partitions separating one principal investigator’s group from another. Bench space is communal, as are the core facilities and common shared equipment such as autoclaves, deep freezers, centrifuges and other common bench-top equipment.

The idea is to mix all researchers together regardless of their research groups in an effort to promote synergy in collaborative research and mutual consult. Where possible, common consumables, equipment and labour are centrally acquired and shared.

MBI’s Internal Component Repository (OpenFreezer)

MBI’s install of OpenFreezer is an online repository collecting and presenting information about the plasmids/clones/drugs/antibodies/chemicals and other resources internally available at MBI. Administered by MBI’s Wet Lab Core, the goal of the resource is to facilitate better communication and more efficient sharing of components among the different groups within MBI. Learn more about the repository, get help or request an account

MBI’s Commitment to Safety

The Mechanobiology Institute is committed to the safety and health of every person  working in MBI labs with the ultimate goal of providing a safe working and learning environment for all. Find out more about MBI’s Occupational Health and Safety resource