Biomaterial shows how ageing in the heart could be reversed

A new lab-grown material has revealed that some of the effects of ageing in the heart may be slowed and even reversed. The discovery could open the door to therapies that rejuvenate the heart by changing its cellular environment, rather than focusing on the heart cells themselves.Learn more

By Lucie Kim|2025-06-18T17:23:36+08:00Jun 18th, 2025|Categories: Science Features|Comments Off on Biomaterial shows how ageing in the heart could be reversed

Rejuvenation of aged egg cells

MBI researchers collaborated with NUS Bia-Echo Asia Centre for Reproductive Longevity and Equality, based at the NUS Yong Loo Lin School of Medicine, to develop an innovative technique to significantly enhance the reproductive potential of aged oocytes, or immature egg cells, potentially paving the way for better outcomes of assisted reproductive technologies, such as in-vitro fertilisation (IVF), for older females. Learn more

By Andrew Wong|2025-06-09T09:27:41+08:00Jun 9th, 2025|Categories: Science Features|Comments Off on Rejuvenation of aged egg cells

A Nervous Contraction

A collaborative study from the Saunders Lab and the Martin-Blanco Lab at the Molecular Biology Institute Barcelona, Spain, demonstrates how the contraction of a Drosophila's ventral nerve cord during development is oscillatory and driven by the combined contractile efforts of individual cells. Learn more

By Shu Chian Tay|2022-05-27T16:46:55+08:00Apr 18th, 2022|Categories: Featured Research, Saunders Lab, Science Features|Comments Off on A Nervous Contraction

The rise of spectro-microscopes

A recent study from the Grenci Lab at the Mechanobiology Institute, National University of Singapore has described a new, highly-sensitive IR spectroscopy technique that overcomes the limitations of existing techniques by utilizing optical components that are commonly used in existing visible light imaging techniques. Learn more

By Management|2021-01-25T14:01:00+08:00Jan 25th, 2021|Categories: Featured Research, Grenci Research, Science Features|Comments Off on The rise of spectro-microscopes

The mechanical editor

A recent study led by Dr. Shaobo Zhang and MBI Principal Investigator Associate Professor Timothy Saunders describes how periodic filopodial retraction caused by the contractile activity of transient Myosin II clusters at the cell leading edge ensures precise matching between primitive heart cells during heart development in Drosophila embryos. Learn more

By Management|2020-10-12T16:43:44+08:00Oct 12th, 2020|Categories: Featured Research, Saunders Lab, Science Features|Comments Off on The mechanical editor

About the National University of Singapore

About NUSA leading global university centred in Asia, NUS is Singapore's flagship university, offering a global approach to education and research with a focus on Asian perspectives and expertise.

About the Mechanobiology Institute, National University of Singapore

About MBIOne of four Research Centres of Excellence at NUS, MBI is working to identify, measure and describe how the forces for motility and morphogenesis are expressed at the molecular, cellular and tissue level.
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