Researchers from the Holle Lab at the Mechanobiology Institute, NUS discover that migration through confined spaces causes lasting nuclear changes in stem cells, biasing them toward bone formation.
Researchers from the Li Lab discover how α5-integrin–FN interactions preserve dermal integrity, offering new insights for antiaging strategies targeting ECM organization and fibroblast function.
Researchers from the Soft Nano-Biomaterials Lab at MBI developed a material system to enable precise investigation into how individual ECM properties affect cultured heart cells.
Researchers from the Toyama Lab at MBI reveal how mechanical factors control apoptosis and cell replacement.
Researchers from the Beghin Lab at the Mechanobiology Institute, NUS combine DeepStar3D algorithm and 3DCellScope interface to develop an experimental tool for real-time interaction with cell data.
Researchers from the Low Lab at MBI discover a crucial role for the scaffold protein BNIP-2 in orchestrating focal adhesion dynamics during early heart development, offering new insights into heart regeneration strategies.
Researchers from the Bershadsky Lab at MBI utilized optogenetics to unlock the role of microtubules in regulating focal adhesion disassembly, an important step in cell migration. http://www.mbi.nus.edu.sg/featured-research/microtubules-and-cell-movement-a-closer-look-at-focal-adhesion-disassembly
Researchers from the Toyama Lab at MBI reveal how mechanical factors control apoptosis and cell replacement. https://www.mbi.nus.edu.sg/featured-research/defining-the-pattern-of-cell-death-and-replacement
A collaborative study between researchers at MBI and scientists locally and overseas discovered how a scaffolding protein synchronizes, in space and time, two important regulatory proteins driving cell migration Learn more
An interdisciplinary team from MBI combined imaging, microfabrication, and biology to develop JeWells - an innovative platform for growing and imaging organoids in 3D. Learn more
A collaboration between MBI scientists and clinical researchers revealed how a scaffolding protein integrates biochemical and mechanical signals to control cardiac muscle cell differentiation. Learn more
A study from the Saunders lab uncovers how random cell fusion events during muscle development are regulated at the tissue level to ensure correct patterning of the muscle architecture. Learn more
A leading global university centred in Asia, NUS is Singapore's flagship university, offering a global approach to education and research with a focus on Asian perspectives and expertise.
One of four Research Centres of Excellence at NUS, MBI is working to identify, measure and describe how the forces for motility and morphogenesis are expressed at the molecular, cellular and tissue level.