The Nano-Heartbuilder: BNIP-2 Influences Mechanosensing in Cardiomyoblast Differentiation

Researchers from the Low Lab at MBI discover a crucial role for the scaffold protein BNIP-2 in orchestrating focal adhesion dynamics during early heart development, offering new insights into heart regeneration strategies.

By Brenda Lau|2025-08-12T13:42:23+08:00Aug 12th, 2025|Categories: Featured Research, Low BC Lab, MBInsights, Science Features|Comments Off on The Nano-Heartbuilder: BNIP-2 Influences Mechanosensing in Cardiomyoblast Differentiation

Shedding Light on Local Microtubule Regulation of Focal Adhesions

Researchers from the Bershadsky Lab at MBI utilized optogenetics to unlock the role of microtubules in regulating focal adhesion disassembly, an important step in cell migration. http://www.mbi.nus.edu.sg/featured-research/microtubules-and-cell-movement-a-closer-look-at-focal-adhesion-disassembly

By Andrew Wong|2025-08-13T09:23:10+08:00Aug 8th, 2025|Categories: Bershadsky Lab, Featured Research, MBInsights, Science Features|Comments Off on Shedding Light on Local Microtubule Regulation of Focal Adhesions

Defining the pattern of cell death and replacement

Researchers from the Toyama Lab at MBI reveal how mechanical factors control apoptosis and cell replacement. https://www.mbi.nus.edu.sg/featured-research/defining-the-pattern-of-cell-death-and-replacement

By Andrew Wong|2024-10-30T13:51:50+08:00Oct 29th, 2024|Categories: Featured Research|Comments Off on Defining the pattern of cell death and replacement

A Nervous Contraction

A collaborative study from the Saunders Lab and the Martin-Blanco Lab at the Molecular Biology Institute Barcelona, Spain, demonstrates how the contraction of a Drosophila's ventral nerve cord during development is oscillatory and driven by the combined contractile efforts of individual cells. Learn more

By Shu Chian Tay|2022-05-27T16:46:55+08:00Apr 18th, 2022|Categories: Featured Research, Saunders Lab, Science Features|Comments Off on A Nervous Contraction

About the National University of Singapore

About NUSA leading global university centred in Asia, NUS is Singapore's flagship university, offering a global approach to education and research with a focus on Asian perspectives and expertise.

About the Mechanobiology Institute, National University of Singapore

About MBIOne of four Research Centres of Excellence at NUS, MBI is working to identify, measure and describe how the forces for motility and morphogenesis are expressed at the molecular, cellular and tissue level.
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