Wu Min Group

Yang YANG

Alumni, Mechanobiology Institute, National University of Singapore

a0095425@u.nus.edu
Level 10 T-Lab
National University of Singapore
5A Engineering Drive 1
Singapore 117411

She is a Scientist: Confidence Formed by Curiosity Over Time

February 11th celebrates The International Day of Women and Girls in Science to promote full, equal access and participation in STEM fields. MBI talks to two of our posdoctoral research fellows about their career as a woman in science.

By Yee Shu Brenda|Feb 11th, 2026|Categories: Chan Lab, Kanchanawong Lab, MBInsights, News, People of MBI|Comments Off on She is a Scientist: Confidence Formed by Curiosity Over Time
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She is Becoming: Curiosity, Comparison and the Making of a Scientist

February 11th celebrates The International Day of Women and Girls in Science to promote full, equal access and participation in STEM fields. MBI talks to two of our PhD students about their journey in becoming a scientist as women.

By Yee Shu Brenda|Feb 11th, 2026|Categories: Dye Lab, Hirashima Lab, MBInsights, News, People of MBI|Comments Off on She is Becoming: Curiosity, Comparison and the Making of a Scientist
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How Structural Imbalance Drives Inflammatory Signaling in Senescent Cells

In a study published in Molecular Biology of the Cell led by Celestine Ho at the Mechanobiology Institute, NUS, researchers discover that HIF-1α-activation in SASP is a defining feature of the SASP induced by diverse stressors, acting independently of micronuclei generation and cGAS/STING activation.

By Yee Shu Brenda|Feb 6th, 2026|Categories: Low BC Lab, Low BC Lab News, MBInsights, Science Features|Comments Off on How Structural Imbalance Drives Inflammatory Signaling in Senescent Cells
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MBI Hosts Students from Sakura High School!

MBI hosted students from Sakura High School, Chiba, Japan on 22nd January 2026 for an outreach session designed to spark curiosity about mechanobiology and research careers.

By Yee Shu Brenda|Jan 26th, 2026|Categories: MBInsights, News|Comments Off on MBI Hosts Students from Sakura High School!
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Yang Yang

Alumni

Principal Investigator

Wu Min

Research Interests

The Cell-Matrix and Cell-Cell Mechanotransduction Group

Recent Publications

  1. Xiong D, Tong C, Fung SYS, McClellan S, Yang Y, Yong J, and Wu M. STIM1 and endoplasmic reticulum-plasma membrane contact sites oscillate independently of calcium-induced calcium release. Open Biol 2026; 16(3). [PMID: 41844235]
  2. De Leoz MLA, Duewer DL, Fung A, Liu L, Yau HK, Potter O, Staples GO, Furuki K, Frenkel R, Hu Y, Sosic Z, Zhang P, Altmann F, Grunwald-Grube C, Shao C, Zaia J, Evers W, Pengelley S, Suckau D, Wiechmann A, Resemann A, Jabs W, Beck A, Froehlich JW, Huang C, Li Y, Liu Y, Sun S, Wang Y, Seo Y, An HJ, Reichardt N, Ruiz JE, Archer-Hartmann S, Azadi P, Bell L, Lakos Z, An Y, Cipollo JF, Pucic-Bakovic M, Štambuk J, Lauc G, Li X, Wang PG, Bock A, Hennig R, Rapp E, Creskey M, Cyr TD, Nakano M, Sugiyama T, Leung PA, Link-Lenczowski P, Jaworek J, Yang S, Zhang H, Kelly T, Klapoetke S, Cao R, Kim JY, Lee HK, Lee JY, Yoo JS, Kim S, Suh S, de Haan N, Falck D, Lageveen-Kammeijer GSM, Wuhrer M, Emery RJ, Kozak RP, Liew LP, Royle L, Urbanowicz PA, Packer NH, Song X, Everest-Dass A, Lattová E, Cajic S, Alagesan K, Kolarich D, Kasali T, Lindo V, Chen Y, Goswami K, Gau B, Amunugama R, Jones R, Stroop CJM, Kato K, Yagi H, Kondo S, Yuen CT, Harazono A, Shi X, Magnelli PE, Kasper BT, Mahal L, Harvey DJ, O'Flaherty R, Rudd PM, Saldova R, Hecht ES, Muddiman DC, Kang J, Bhoskar P, Menard D, Saati A, Merle C, Mast S, Tep S, Truong J, Nishikaze T, Sekiya S, Shafer A, Funaoka S, Toyoda M, de Vreugd P, Caron C, Pradhan P, Tan NC, Mechref Y, Patil S, Rohrer JS, Chakrabarti R, Dadke D, Lahori M, Zou C, Cairo C, Reiz B, Whittal RM, Lebrilla CB, Wu L, Guttman A, Szigeti M, Kremkow BG, Lee KH, Sihlbom C, Adamczyk B, Jin C, Karlsson NG, Örnros J, Larson G, Nilsson J, Meyer B, Wiegandt A, Komatsu E, Perreault H, Bodnar ED, Said N, Francois Y, Leize-Wagner E, Maier S, Zeck A, Heck AJR, Yang Y, Haselberg R, Yu YQ, Alley W, Leone JW, Yuan H, and Stein SE. NIST Interlaboratory Study on Glycosylation Analysis of Monoclonal Antibodies: Comparison of Results from Diverse Analytical Methods. Mol Cell Proteomics 2019; 19(1):11-30. [PMID: 31591262]
  3. Chen Y, Yong J, Martínez-Sánchez A, Yang Y, Wu Y, De Camilli P, Fernández-Busnadiego R, and Wu M. Dynamic instability of clathrin assembly provides proofreading control for endocytosis. J. Cell Biol. 2019;. [PMID: 31451612]
  4. Yang Y, and Wu M. Rhythmicity and waves in the cortex of single cells. Philos. Trans. R. Soc. Lond., B, Biol. Sci. 2018; 373(1747). [PMID: 29632268]
  5. Yang Y, Xiong D, Pipathsouk A, Weiner OD, and Wu M. Clathrin Assembly Defines the Onset and Geometry of Cortical Patterning. Dev. Cell 2017; 43(4):507-521.e4. [PMID: 29161594]
  6. Xiao S, Tong C, Yang Y, and Wu M. Mitotic Cortical Waves Predict Future Division Sites by Encoding Positional and Size Information. Dev. Cell 2017; 43(4):493-506.e3. [PMID: 29161593]

By Management|2018-03-21T09:53:35+08:00Apr 19th, 2017|Categories: Alumni|Comments Off on Yang Yang

MBI

Decoding the living machine

At the Mechanobiology Institute, National University of Singapore, our goal is to develop the world’s leading centre for mechanobiology research and education. Our research aims to interrogate biological systems from a physical and mechanical perspective at the molecular, cellular, and tissue level, with the eventual goal to leverage basic science discoveries in mechanobiology into biomedical innovations.

MBI gratefully acknowledges support from:

National University of Singapore

National Research Foundation Singapore

Ministry of Education Singapore

Contact us

Mechanobiology Institute (MBI)

National University of Singapore
    T-Lab, #10-01
    5A Engineering Drive 1
    Singapore 117411

Campus map

  mbi.nus.edu.sg
  mbi@nus.edu.sg
  +65 6601 5424

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About the National University of Singapore

About NUSA leading global university centred in Asia, NUS is Singapore's flagship university, offering a global approach to education and research with a focus on Asian perspectives and expertise.

About the Mechanobiology Institute, National University of Singapore

About MBIOne of four Research Centres of Excellence at NUS, MBI is working to identify, measure and describe how the forces for motility and morphogenesis are expressed at the molecular, cellular and tissue level.
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