WU Min
Collaborator, Mechanobiology Institute, National University of Singapore
dbswum@nus.edu.sg
+65 6601 2310
CBIS Blk S1A, Level 2 Lee Wee Kheng Bldg
National University of Singapore
14 Science Drive 4
Singapore 117557
Laboratory website
Wu Lab Deconstructing the Endocytic Machinery
Research Program
The Cell-Matrix and Cell-Cell Mechanotransduction Group
Affiliations
Department of Biological Sciences, National University of Singapore
Synchrony of Waves
The collective dynamics of endocytosis
Wu Min
Collaborator
Research Areas
Endocytosis, Membrane traffic, Curvature, Actin cytoskeleton, Mechanotransduction
Research Interests
Dr Wu is interested in elucidating the principles underlying the organization and dynamics of the subcellular membrane compartments. Specifically her lab investigates how biological membranes are shaped through collective protein-lipid interactions and how geometry of the membrane compartment is coupled to cellular functions. The Wu Lab uses a combination of cell biological, biophysical and biochemical approaches to address these questions.
Biography
Dr Wu Min graduated from Peking University in China and received her bachelor degree in Chemistry. She did her graduate studies at Cornell University with Dr Barbara Baird, where she initiated the use of patterned lipid bilayers as antigen-presenting platforms and studied immune cell activation and signal transduction. During her post-doctoral research in the laboratory of Dr Pietro De Camilli at Yale School of Medicine, she focused on the molecular mechanisms of endocytosis. In 2011, she was awarded the NRF fellowship, joining CBIS/MBI in the fall.
Education
PhD Cornell University
Recent Publications
- Chua XL, Tong CS, Su M, Xǔ XJ, Xiao S, Wu X, and Wu M. Competition and synergy of Arp2/3 and formins in nucleating actin waves. Cell Rep 2024; 43(7):114423. [PMID: 38968072]
- Tong CS, Su M, Sun H, Chua XL, Xiong D, Guo S, Raj R, Ong NWP, Lee AG, Miao Y, and Wu M. Collective dynamics of actin and microtubule and its crosstalk mediated by FHDC1. Front Cell Dev Biol 2024; 11:1261117. [PMID: 38567385]
- Le Chua X, Tong CS, Xǔ XJ, Su M, Xiao S, Wu X, and Wu M. Competition and Synergy of Arp2/3 and Formins in Nucleating Actin Waves. bioRxiv 2023;. [PMID: 37745345]
- Su M, Zhuang Y, Miao X, Zeng Y, Gao W, Zhao W, and Wu M. Comparative Study of Curvature Sensing Mediated by F-BAR and an Intrinsically Disordered Region of FBP17. iScience 2020; 23(11):101712. [PMID: 33205024]
- Chen Y, Yong J, Martínez-Sánchez A, Yang Y, Wu Y, De Camilli P, Fernández-Busnadiego R, and Wu M. Dynamic instability of clathrin assembly provides proofreading control for endocytosis. J. Cell Biol. 2019;. [PMID: 31451612]
- . https://www.ncbi.nlm.nih.gov/pubmed/31390543
- Yong J, Chen Y, and Wu M. Real-Time Monitoring of Clathrin Assembly Kinetics in a Reconstituted System. Methods Mol. Biol. 2018; 1847:177-187. [PMID: 30129017]
- Yang Y, and Wu M. Rhythmicity and waves in the cortex of single cells. Philos. Trans. R. Soc. Lond., B, Biol. Sci. 2018; 373(1747). [PMID: 29632268]
- McPherson PS, and Wu M. Light, space, and time in cancer signaling. Mol. Biol. Cell 2018; 29(6):688. [PMID: 29535172]
- Wu Z, Su M, Tong C, Wu M, and Liu J. Membrane shape-mediated wave propagation of cortical protein dynamics. Nat Commun 2018; 9(1):136. [PMID: 29321558]
Lab Members
Hann Shen Ng
Research Fellow, Holle Group
Congratulations to Kim Whye and Jake for their recent achievements
Congrats to Kim Whye for being selected to give an oral presentation and for receiving a travel award for the upcoming Imaging Mouse Development Workshop! Congrats also to Jake for being awarded the prestigious EMBL CPP grant to engage in collaboration with the Prevedel lab!
Joe invited to present at various conferences and research institutes in Japan
Joe was invited to present at the International Symposium on Mechanical control of biological self-organization and the IUPAB Congress 2024 in Kyoto, as well as at WPI-PRIMe in Osaka. It was also a great pleasure to meet up with Katsuhiko Hayashi, an inspiring figure in ovaroids studies!
Push and pull: Joe shares his two cents on current approaches to measuring mechanics in Nature
Great to see developmental mechanics getting highlighted!
Shambhavi Dikshit
Research Fellow, Toyama Group
Nishanth Venugopal Menon
Senior Research Fellow, Lim Group
Prof Rong Li elected President of the American Society for Cell Biology for 2026
MBI Director Professor Rong Li, has been elected by members of the American Society for Cell Biology (ASCB) to serve as President of the Society in 2026. She will serve as President-Elect on the ASCB Executive Committee beginning 1 January 2025, before starting her term as President on 1 January 2026.
Prof Lim Chwee Teck elected Fellow of the Royal Society
MBI Principal Investigator Professor Lim Chwee Teck, Director of the Institute for Health Innovation & Technology at the National University of Singapore (NUS iHealthtech) and NUSS Professor, has been elected to the prestigious Fellowship of the Royal Society
The first research article from the Chan Lab is up on bioRxiv now
Congratulations to Arikta for driving this project!
Congrats to Kim Whye, Boon Heng and Kosei for their accomplishments at the SCBS Annual Conference 2024!
Congratulations to Kim Whye and Boon Heng (below) for presenting their latest research on ovarian follicle development and to Kosei for being awarded the 'Best Poster Prize' at the SCBS Annual Conference 2024.
Seeking Research Assistant in Assoc. Prof. Low Boon Chuan’s Lab at MBI, NUS
We seek to recruit a Research Assistant in Assoc Prof. Low Boon Chuan's Lab at the Mechanobiology Institute, NUS.
Joe shares latest work on ovarian mechanobiology at the ACRLE Conference 2024
Joe presents the lab's latest work on murine ovary elasticity at the ACRLE Conference 2024.
