Mapping the Interactome
Proteomics reveals the E-cadherin interaction network
Theories and Milestones
The field of mechanobiology has grown dramatically in the past decade. With this growth came ground breaking experiments, and findings that challenged the foundations of cell biology.
How Cells Repair Wounds
Collaborative study identifies new mechanism for wound healing
Unraveling a-catenin
α-catenin mediated mechanosensing of cell-cell junctions
Protecting the Genome
ATR responds to mechanical stimuli to protect DNA
Capturing E-cadherin
Dynamics of cortical actin in the recruitment o cadherin at adhesion sites
Ding Wei Yung
Alumni
Principal Investigator
Research Interests
Cell-Matrix and Cell-Cell Mechanotransduction, Molecular Mechanisms of Mechanobiology
Wei Yung’s interest lies in understanding the sophistication of cells as robust machines. Using C. elegans, a 1mm nematode, as a model system, he investigates the cellular machinery underlying newly fertilized zygotes that drives critical force-dependent processes such as polarization and cytokinesis.
Biography
Wei Yung completed his Bachelor’s degree in Bioengineering (Second Class Upper) from the National University of Singapore in 2012. In his honors dissertation under the co-supervision of Professor James Goh and Professor Wong Hee Kit, he optimized the conditions required for the construction of interbody spinal fusion device using primary adipose stem cells seeded in a biodegradable polycaprolactone/tricalcium sulphate (PCL/TCP) scaffold. The work was presented in the Bioengineering Showcase 2012 and he was awarded the Best Poster Award. After he was enrolled in the Mechanobiology Graduate Program, he joined Dr. Zaidel-Bar’s Cell Adhesion and Morphogenesis Lab and is currently searching for novel genes involved in regulating C. elegans early embryogenesis.
