Why do Cells Stretch?
Cyclic stretching helps soft tissues spread and grow
Modeling Concentration Gradients
Clustering drives formation of subcellular morphogen gradients
Forcing Wounds Closed
A cellular tug-of-war mechanically drives gap closure
Defining Adhesion Clusters
Visualizing the building blocks of cell-cell adhesion
Corinna Lim and Jolene Tan from Singapore’s Association of Women for Action and Research (AWARE)
Members of MBI WIS welcomed Corinna Lim and Jolene Tan of AWARE for a brown bag session on women’s issues in science
Epithelial Tube Contraction
A new feedback mechanism for regulating contractility
Ding Wei Yung
Alumni
Principal Investigator
Research Interests
Cell-Matrix and Cell-Cell Mechanotransduction, Molecular Mechanisms of Mechanobiology
Wei Yung’s interest lies in understanding the sophistication of cells as robust machines. Using C. elegans, a 1mm nematode, as a model system, he investigates the cellular machinery underlying newly fertilized zygotes that drives critical force-dependent processes such as polarization and cytokinesis.
Biography
Wei Yung completed his Bachelor’s degree in Bioengineering (Second Class Upper) from the National University of Singapore in 2012. In his honors dissertation under the co-supervision of Professor James Goh and Professor Wong Hee Kit, he optimized the conditions required for the construction of interbody spinal fusion device using primary adipose stem cells seeded in a biodegradable polycaprolactone/tricalcium sulphate (PCL/TCP) scaffold. The work was presented in the Bioengineering Showcase 2012 and he was awarded the Best Poster Award. After he was enrolled in the Mechanobiology Graduate Program, he joined Dr. Zaidel-Bar’s Cell Adhesion and Morphogenesis Lab and is currently searching for novel genes involved in regulating C. elegans early embryogenesis.
