Cell Extrusion Mechanisms
Making sure to expel an unwanted cell
A Moving Story of FHL2
How FHL2 translocates to the nucleus under low tension
2016 MBI-BPS Thematic Meeting on the Mechanobiology of Disease
Recent meeting brings together scientists to discuss research on the physical basis of disease
Elongation by Contraction
Pulling forces drive changes in cell shape
Decisions in a Pinch
Receptor Tyrosince Kinases control mechanosensors
A Cellular Shock Absorber
How talin structure makes it an ideal force buffer
Ding Wei Yung
Alumni
Principal Investigator
Research Interests
Cell-Matrix and Cell-Cell Mechanotransduction, Molecular Mechanisms of Mechanobiology
Wei Yung’s interest lies in understanding the sophistication of cells as robust machines. Using C. elegans, a 1mm nematode, as a model system, he investigates the cellular machinery underlying newly fertilized zygotes that drives critical force-dependent processes such as polarization and cytokinesis.
Biography
Wei Yung completed his Bachelor’s degree in Bioengineering (Second Class Upper) from the National University of Singapore in 2012. In his honors dissertation under the co-supervision of Professor James Goh and Professor Wong Hee Kit, he optimized the conditions required for the construction of interbody spinal fusion device using primary adipose stem cells seeded in a biodegradable polycaprolactone/tricalcium sulphate (PCL/TCP) scaffold. The work was presented in the Bioengineering Showcase 2012 and he was awarded the Best Poster Award. After he was enrolled in the Mechanobiology Graduate Program, he joined Dr. Zaidel-Bar’s Cell Adhesion and Morphogenesis Lab and is currently searching for novel genes involved in regulating C. elegans early embryogenesis.
