WU Min
Collaborator, Mechanobiology Institute, National University of Singapore
dbswum@nus.edu.sg
+65 6601 2310
CBIS Blk S1A, Level 2 Lee Wee Kheng Bldg
National University of Singapore
14 Science Drive 4
Singapore 117557
Laboratory website
Wu Lab Deconstructing the Endocytic Machinery
Research Program
The Cell-Matrix and Cell-Cell Mechanotransduction Group
Affiliations
Department of Biological Sciences, National University of Singapore
Katherine Anne Lau Enqi
Research Assistant, Young Group
Zhou Hanzhang
Research Fellow, Yu Group
Dongyu Xu
Research Fellow, Yu Group
Li Guang
Research Fellow, Yu Group
Seeking Research Assistant in the research group of Prof. Rong Li at the Mechanobiology Institute, NUS
The Mechanobiology Institute, NUS, seeks to recruit a Research Assistant in the research group of Prof. Rong Li.
Check out the lab’s latest publication and preprint!
Access the publication or the preprint here!
Wu Min
Collaborator
Research Areas
Endocytosis, Membrane traffic, Curvature, Actin cytoskeleton, Mechanotransduction
Research Interests
Dr Wu is interested in elucidating the principles underlying the organization and dynamics of the subcellular membrane compartments. Specifically her lab investigates how biological membranes are shaped through collective protein-lipid interactions and how geometry of the membrane compartment is coupled to cellular functions. The Wu Lab uses a combination of cell biological, biophysical and biochemical approaches to address these questions.
Biography
Dr Wu Min graduated from Peking University in China and received her bachelor degree in Chemistry. She did her graduate studies at Cornell University with Dr Barbara Baird, where she initiated the use of patterned lipid bilayers as antigen-presenting platforms and studied immune cell activation and signal transduction. During her post-doctoral research in the laboratory of Dr Pietro De Camilli at Yale School of Medicine, she focused on the molecular mechanisms of endocytosis. In 2011, she was awarded the NRF fellowship, joining CBIS/MBI in the fall.
Education
PhD Cornell University
Recent Publications
- Xiong D, Tong C, Fung SYS, McClellan S, Yang Y, Yong J, and Wu M. STIM1 and endoplasmic reticulum-plasma membrane contact sites oscillate independently of calcium-induced calcium release. Open Biol 2026; 16(3). [PMID: 41844235]
- Chua XL, Tong CS, Su M, Xǔ XJ, Xiao S, Wu X, and Wu M. Competition and synergy of Arp2/3 and formins in nucleating actin waves. Cell Rep 2024; 43(7):114423. [PMID: 38968072]
- Tong CS, Su M, Sun H, Chua XL, Xiong D, Guo S, Raj R, Ong NWP, Lee AG, Miao Y, and Wu M. Collective dynamics of actin and microtubule and its crosstalk mediated by FHDC1. Front Cell Dev Biol 2024; 11:1261117. [PMID: 38567385]
- Le Chua X, Tong CS, Xǔ XJ, Su M, Xiao S, Wu X, and Wu M. Competition and Synergy of Arp2/3 and Formins in Nucleating Actin Waves. bioRxiv 2023;. [PMID: 37745345]
- Su M, Zhuang Y, Miao X, Zeng Y, Gao W, Zhao W, and Wu M. Comparative Study of Curvature Sensing Mediated by F-BAR and an Intrinsically Disordered Region of FBP17. iScience 2020; 23(11):101712. [PMID: 33205024]
- Chen Y, Yong J, Martínez-Sánchez A, Yang Y, Wu Y, De Camilli P, Fernández-Busnadiego R, and Wu M. Dynamic instability of clathrin assembly provides proofreading control for endocytosis. J. Cell Biol. 2019;. [PMID: 31451612]
- . https://www.ncbi.nlm.nih.gov/pubmed/31390543
- Yong J, Chen Y, and Wu M. Real-Time Monitoring of Clathrin Assembly Kinetics in a Reconstituted System. Methods Mol. Biol. 2018; 1847:177-187. [PMID: 30129017]
- Yang Y, and Wu M. Rhythmicity and waves in the cortex of single cells. Philos. Trans. R. Soc. Lond., B, Biol. Sci. 2018; 373(1747). [PMID: 29632268]
- McPherson PS, and Wu M. Light, space, and time in cancer signaling. Mol. Biol. Cell 2018; 29(6):688. [PMID: 29535172]
Lab Members
EASMB Symposium 2025 Showcases Global Participation and Relevance
The East Asian Single-Molecule Biophysics Symposium 2025 (EASMB2025) held from 24 to 26 November at the Ngee Ann Kongsi Auditorium in the Education Resource Centre, UTown, National University of Singapore showcased global participation and relevance.
Ng Inn Chuan
Research Associate, Yu Group
Byun Young Seo Christina
Research Assistant, Tee Group
Super proud of Arikta Biswas, whose work on theca cell mechanics and compressive stress is now published in Nature Communications!
A huge thanks to our collaborators and reviewers for offering their invaluable feedback as well! Read the article here.
The Pressure That Shapes Life: Mechanical Forces Behind Egg Maturation
Researchers from the Chan Lab at MBI demonstrate the importance of compressive stress exhibited by theca cells in healthy follicle maturation and surrounding support cells, suggesting a new perspective in understanding infertility.
Luo Xujie
Research Assistant, Lim Group
Prof. Lim Chwee Teck elected as an FREng, and received the Otto Schmitt Award
Professor Lim Chwee Teck elected as an International Fellow of the Royal Academy of Engineering and received the Otto Schmitt Award from IFMBE
Yee Zhuangli
Research Fellow, Low Group
Quantitative Micro-Elastography: New Imaging Tool Uncovers Age-Dependent Mechanical Changes in Ovarian Tissue
Researchers from the Chan Lab at MBI develop a a novel method called quantitative micro-elastography to create detailed 3D maps of ovarian stiffness in mice—revealing crucial insights that could lead to new infertility treatments.
Jie Zhang
Research Fellow, Lim Group
Sui Mingyu
Research Fellow, Yan Jie Group
MBI-MPG Conference 2025: Mechanobiology in Space and Time
The MBI-MPG Conference 2025 was held from 9-12th September at the Mechanobiology Institute, National University of Singapore.
