Yan Jie Lab

The Nano-Heartbuilder: BNIP-2 Influences Mechanosensing in Cardiomyoblast Differentiation

Researchers from the Low Lab at MBI discover a crucial role for the scaffold protein BNIP-2 in orchestrating focal adhesion dynamics during early heart development, offering new insights into heart regeneration strategies.

By Yee Shu Brenda|Aug 12th, 2025|Categories: Featured Research, Low BC Lab, MBInsights, Science Features|Comments Off on The Nano-Heartbuilder: BNIP-2 Influences Mechanosensing in Cardiomyoblast Differentiation
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Shedding Light on Local Microtubule Regulation of Focal Adhesions

Researchers from the Bershadsky Lab at MBI utilized optogenetics to unlock the role of microtubules in regulating focal adhesion disassembly, an important step in cell migration. http://www.mbi.nus.edu.sg/featured-research/microtubules-and-cell-movement-a-closer-look-at-focal-adhesion-disassembly

By Andrew Wong|Aug 8th, 2025|Categories: Bershadsky Lab, Featured Research, MBInsights, Science Features|Comments Off on Shedding Light on Local Microtubule Regulation of Focal Adhesions
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A Warm Welcome to the 2025 Ph.D Cohort!

MBI is delighted to welcome the 2025 cohort of Ph.D students. Coming from a rich tapestry of countries – China, Vietnam, Singapore, India and the Philippines – these eleven outstanding individuals bring with them interdisciplinary expertise and fresh perspectives that will enrich MBI’s vibrant research community.

By Yee Shu Brenda|Aug 7th, 2025|Categories: News|Comments Off on A Warm Welcome to the 2025 Ph.D Cohort!
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Artem K Efremov (Yefremov)

Alumni 2013 – 2021
Visiting Senior Research Fellow

Principal Investigator

Yan Jie

By Management|2021-10-26T13:44:01+08:00Apr 20th, 2017|Categories: Alumni, Visiting Faculty, Visiting Scientists, Yan Jie Alumni|Comments Off on Artem Yefremov

MBI

Decoding the living machine

At the Mechanobiology Institute, National University of Singapore, our goal is to develop the world’s leading centre for mechanobiology research and education. Our research aims to interrogate biological systems from a physical and mechanical perspective at the molecular, cellular, and tissue level, with the eventual goal to leverage basic science discoveries in mechanobiology into biomedical innovations.

MBI gratefully acknowledges support from:

National University of Singapore

National Research Foundation Singapore

Ministry of Education Singapore

Contact us

Mechanobiology Institute (MBI)

National University of Singapore
    T-Lab, #10-01
    5A Engineering Drive 1
    Singapore 117411

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  mbi.nus.edu.sg
  mbi@nus.edu.sg
  +65 6601 5424

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About the National University of Singapore

About NUSA leading global university centred in Asia, NUS is Singapore's flagship university, offering a global approach to education and research with a focus on Asian perspectives and expertise.

About the Mechanobiology Institute, National University of Singapore

About MBIOne of four Research Centres of Excellence at NUS, MBI is working to identify, measure and describe how the forces for motility and morphogenesis are expressed at the molecular, cellular and tissue level.
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