TEE Yee Han
MBI Fellow, Mechanobiology Institute, National University of Singapore
mbityh@nus.edu.sg
Level 10 T-Lab
National University of Singapore
5A Engineering Drive 1
Singapore 117411
Seeking Research Fellow in Transmission Electron Microscopy at the Mechanobiology Institute, NUS
We are seeking a Research Fellow in Transmission Electron Microscopy at the Mechanobiology Institute, NUS
Hu Yuqi
Research Assistant, Yu Group
The Nano-Heartbuilder: BNIP-2 Influences Mechanosensing in Cardiomyoblast Differentiation
Researchers from the Low Lab at MBI discover a crucial role for the scaffold protein BNIP-2 in orchestrating focal adhesion dynamics during early heart development, offering new insights into heart regeneration strategies.
Shedding Light on Local Microtubule Regulation of Focal Adhesions
Researchers from the Bershadsky Lab at MBI utilized optogenetics to unlock the role of microtubules in regulating focal adhesion disassembly, an important step in cell migration. http://www.mbi.nus.edu.sg/featured-research/microtubules-and-cell-movement-a-closer-look-at-focal-adhesion-disassembly
Tee Yee Han
MBI Fellow
Principal Investigator
Research Interests
Recent Publications
- Naripogu KB, Tee YH, Senju Y, Bershadsky A, and Robinson RC. Localization of Asgard archaeal ESCRT proteins to eukaryotic cellular structures. Biochem Biophys Res Commun 2026; 802:153301. [PMID: 41576632]
- Tsikolia N, Nguyen DTL, and Tee YH. Mechanisms of left-right symmetry breaking across scales. Curr Opin Cell Biol 2025; 95:102564. [PMID: 40544609]
- Glazenburg MM, Hettema NM, Laan L, Remy O, Laloux G, Brunet T, Chen X, Tee YH, Wen W, Rizvi MS, Jolly MK, and Riddell M. Perspectives on polarity - exploring biological asymmetry across scales. J Cell Sci 2024; 137(5). [PMID: 38441500]
- Tee YH, Goh WJ, Yong X, Ong HT, Hu J, Tay IYY, Shi S, Jalal S, Barnett SFH, Kanchanawong P, Huang W, Yan J, Lim YAB, Thiagarajan V, Mogilner A, and Bershadsky AD. Actin polymerisation and crosslinking drive left-right asymmetry in single cell and cell collectives. Nat Commun 2023; 14(1):776. [PMID: 36774346]
- Efremov AK, Yao M, Sun Y, Tee YH, Sheetz MP, Bershadsky AD, Martinac B, and Yan J. Application of piconewton forces to individual filopodia reveals mechanosensory role of L-type Ca2+ channels. Biomaterials 2022; 284:121477. [PMID: 35395455]
- Jalal S, Shi S, Acharya V, Huang RY, Viasnoff V, Bershadsky A, and Tee YH. Actin cytoskeleton self-organization in single epithelial cells and fibroblasts under isotropic confinement. J. Cell. Sci. 2019;. [PMID: 30787030]
- Lou Y, Toh TC, Tee YH, and Yu H. 25-Hydroxyvitamin D3 induces osteogenic differentiation of human mesenchymal stem cells. Sci Rep 2017; 7:42816. [PMID: 28211493]
- Hu S, Dasbiswas K, Guo Z, Tee Y, Thiagarajan V, Hersen P, Chew T, Safran SA, Zaidel-Bar R, and Bershadsky AD. Long-range self-organization of cytoskeletal myosin II filament stacks. Nat. Cell Biol. 2017;. [PMID: 28114270]
- Tee YH, and Bershadsky AD. Actin Retrograde Flow in Permeabilized Cells: Myosin-II Driven Centripetal Movement of Transverse Arcs. Bio Protoc 2016; 6(5):e1743. [PMID: 40656211]
- Hu S, Tee Y, Kabla A, Zaidel-Bar R, Bershadsky A, and Hersen P. Structured illumination microscopy reveals focal adhesions are composed of linear subunits. Cytoskeleton (Hoboken) 2015; 72(5):235-45. [PMID: 26012525]
Lab Members
