The Pressure That Shapes Life: Mechanical Forces Behind Egg Maturation

Researchers from the Chan Lab at MBI demonstrate the importance of compressive stress exhibited by theca cells in healthy follicle maturation and surrounding support cells, suggesting a new perspective in understanding infertility.

By Brenda Lau|2025-10-31T18:23:43+08:00Oct 31st, 2025|Categories: Chan Lab News, MBInsights, Science Features|Comments Off on The Pressure That Shapes Life: Mechanical Forces Behind Egg Maturation

Quantitative Micro-Elastography: New Imaging Tool Uncovers Age-Dependent Mechanical Changes in Ovarian Tissue

Researchers from the Chan Lab at MBI develop a a novel method called quantitative micro-elastography to create detailed 3D maps of ovarian stiffness in mice—revealing crucial insights that could lead to new infertility treatments.

By Brenda Lau|2025-10-31T10:43:54+08:00Oct 14th, 2025|Categories: Chan Lab News, MBInsights, Science Features|Comments Off on Quantitative Micro-Elastography: New Imaging Tool Uncovers Age-Dependent Mechanical Changes in Ovarian Tissue

The Chan Lab at the MBI-MPG Conference 2025!

Congratulations to Kim Whye and Kosei for being selected for talks, and Boon Heng for winning the 'Best Poster' prize! Thanks to all who gave feedback on our work!

By Lois Yaw|2025-09-15T16:54:21+08:00Sep 15th, 2025|Categories: Chan Lab News|Comments Off on The Chan Lab at the MBI-MPG Conference 2025!

Congratulations to Wee Juin Shin for being selected to present his work at the Amgen Scholars Asia Symposium!

Our Amgen scholar, Wee Juin Shin, has been selected to present his work on ‘the Influence of substrate curvature on theca cell nematic flow’, at the Amgen Scholar Asia Symposium in Kyoto!

By Lois Yaw|2025-09-30T11:35:30+08:00Jul 29th, 2025|Categories: Chan Lab News|Comments Off on Congratulations to Wee Juin Shin for being selected to present his work at the Amgen Scholars Asia Symposium!

Congratulations to Kim Whye Leong for presenting excellent work at the Imaging Mouse Development Workshop held at EMBL Heidelberg!

Congratulations to Kim Whye Leong for presenting excellent work at the Imaging Mouse Development Workshop held at EMBL Heidelberg from 2 to 5 Sept 2024. Thanks for all the feedback from the expert audience!

By Lois Yaw|2024-09-16T10:25:45+08:00Sep 16th, 2024|Categories: Chan Lab News|Comments Off on Congratulations to Kim Whye Leong for presenting excellent work at the Imaging Mouse Development Workshop held at EMBL Heidelberg!

Welcome to Daniel!

Daniel is a UROP intern who will be applying a machine learning approach to study follicle development.

By Lois Yaw|2024-08-26T14:44:23+08:00Aug 26th, 2024|Categories: Chan Lab News|Comments Off on Welcome to Daniel!

About the National University of Singapore

About NUSA leading global university centred in Asia, NUS is Singapore's flagship university, offering a global approach to education and research with a focus on Asian perspectives and expertise.

About the Mechanobiology Institute, National University of Singapore

About MBIOne of four Research Centres of Excellence at NUS, MBI is working to identify, measure and describe how the forces for motility and morphogenesis are expressed at the molecular, cellular and tissue level.
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