Saunders Group

The Nano-Heartbuilder: BNIP-2 Influences Mechanosensing in Cardiomyoblast Differentiation

Researchers from the Low Lab at MBI discover a crucial role for the scaffold protein BNIP-2 in orchestrating focal adhesion dynamics during early heart development, offering new insights into heart regeneration strategies.

By Yee Shu Brenda|Aug 12th, 2025|Categories: Featured Research, Low BC Lab, MBInsights, Science Features|Comments Off on The Nano-Heartbuilder: BNIP-2 Influences Mechanosensing in Cardiomyoblast Differentiation

Shedding Light on Local Microtubule Regulation of Focal Adhesions

Researchers from the Bershadsky Lab at MBI utilized optogenetics to unlock the role of microtubules in regulating focal adhesion disassembly, an important step in cell migration. http://www.mbi.nus.edu.sg/featured-research/microtubules-and-cell-movement-a-closer-look-at-focal-adhesion-disassembly

By Andrew Wong|Aug 8th, 2025|Categories: Bershadsky Lab, Featured Research, MBInsights, Science Features|Comments Off on Shedding Light on Local Microtubule Regulation of Focal Adhesions

A Warm Welcome to the 2025 Ph.D Cohort!

MBI is delighted to welcome the 2025 cohort of Ph.D students. Coming from a rich tapestry of countries – China, Vietnam, Singapore, India and the Philippines – these eleven outstanding individuals bring with them interdisciplinary expertise and fresh perspectives that will enrich MBI’s vibrant research community.

By Yee Shu Brenda|Aug 7th, 2025|Categories: News|Comments Off on A Warm Welcome to the 2025 Ph.D Cohort!

Zhang Shaobo

Alumni

Principal Investigator

Timothy Saunders

Research Interests

Mechanotransduction in Tissues Group

I joined the Saunders group on an internship as part of my Final Year Project during undergraduate study. The internship has been an amazing experience and helped me make up my mind to continue my journey in the mechanics of development – an exciting field which requires the integration of biology, physics, computer science and engineering.

My background during undergraduate study is in Bioinformatics (at Shanghai Jiao Tong University), and this has prepared me well for future exploration. I hope to use quantitative analysis techniques to study robust and precise cell matching processes. By applying embryonic Drosophila heart formation as a simplified matching system, I am looking forward to deciphering the deeper mechanisms of the cell targeting process about how cells find their partners in a complicated environment.

By Management|2020-10-21T10:04:29+08:00Apr 11th, 2017|Categories: Alumni|Comments Off on Zhang Shaobo

About the National University of Singapore

About NUSA leading global university centred in Asia, NUS is Singapore's flagship university, offering a global approach to education and research with a focus on Asian perspectives and expertise.

About the Mechanobiology Institute, National University of Singapore

About MBIOne of four Research Centres of Excellence at NUS, MBI is working to identify, measure and describe how the forces for motility and morphogenesis are expressed at the molecular, cellular and tissue level.
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