Toyama Group

Yusuke HARA

Alumni, Mechanobiology Institute, National University of Singapore

mbiyusu@nus.edu.sg
Level 10 T-Lab
National University of Singapore
5A Engineering Drive 1
Singapore 117411

She is a Scientist: Confidence Formed by Curiosity Over Time

February 11th celebrates The International Day of Women and Girls in Science to promote full, equal access and participation in STEM fields. MBI talks to two of our posdoctoral research fellows about their career as a woman in science.

By Yee Shu Brenda|Feb 11th, 2026|Categories: Chan Lab, Kanchanawong Lab, MBInsights, News, People of MBI|Comments Off on She is a Scientist: Confidence Formed by Curiosity Over Time

She is Becoming: Curiosity, Comparison and the Making of a Scientist

February 11th celebrates The International Day of Women and Girls in Science to promote full, equal access and participation in STEM fields. MBI talks to two of our PhD students about their journey in becoming a scientist as women.

By Yee Shu Brenda|Feb 11th, 2026|Categories: Dye Lab, Hirashima Lab, MBInsights, News, People of MBI|Comments Off on She is Becoming: Curiosity, Comparison and the Making of a Scientist

How Structural Imbalance Drives Inflammatory Signaling in Senescent Cells

In a study published in Molecular Biology of the Cell led by Celestine Ho at the Mechanobiology Institute, NUS, researchers discover that HIF-1α-activation in SASP is a defining feature of the SASP induced by diverse stressors, acting independently of micronuclei generation and cGAS/STING activation.

By Yee Shu Brenda|Feb 6th, 2026|Categories: Low BC Lab, Low BC Lab News, MBInsights, Science Features|Comments Off on How Structural Imbalance Drives Inflammatory Signaling in Senescent Cells

MBI Hosts Students from Sakura High School!

MBI hosted students from Sakura High School, Chiba, Japan on 22nd January 2026 for an outreach session designed to spark curiosity about mechanobiology and research careers.

By Yee Shu Brenda|Jan 26th, 2026|Categories: MBInsights, News|Comments Off on MBI Hosts Students from Sakura High School!

Yusuke Hara

Alumni

Principal Investigator

Yusuke Toyama

Research Interests

Mechanotransduction in Tissues

Recent Publications

  1. Sun Z, Amourda C, Shagirov M, Hara Y, Saunders TE, and Toyama Y. Author Correction: Basolateral protrusion and apical contraction cooperatively drive Drosophila germ-band extension. Nat. Cell Biol. 2018;. [PMID: 29507405]
  2. Hara Y. Contraction and elongation: Mechanics underlying cell boundary deformations in epithelial tissue. Dev. Growth Differ. 2017;. [PMID: 28573735]
  3. Ding WY, Ong HT, Hara Y, Wongsantichon J, Toyama Y, Robinson RC, Nédélec F, and Zaidel-Bar R. Plastin increases cortical connectivity to facilitate robust polarization and timely cytokinesis. J. Cell Biol. 2017;. [PMID: 28400443]
  4. Sun Z, Amourda C, Shagirov M, Hara Y, Saunders TE, and Toyama Y. Basolateral protrusion and apical contraction cooperatively drive Drosophila germ-band extension. Nat. Cell Biol. 2017;. [PMID: 28346438]
  5. Bertocchi C, Wang Y, Ravasio A, Hara Y, Wu Y, Sailov T, Baird MA, Davidson MW, Zaidel-Bar R, Toyama Y, Ladoux B, Mege R, and Kanchanawong P. Nanoscale architecture of cadherin-based cell adhesions. Nat. Cell Biol. 2016;. [PMID: 27992406]
  6. Hara Y, Shagirov M, and Toyama Y. Cell Boundary Elongation by Non-autonomous Contractility in Cell Oscillation. Curr. Biol. 2016; 26(17):2388-96. [PMID: 27524484]
By Management|2018-02-20T13:14:57+08:00Apr 20th, 2017|Categories: Alumni, Toyama Alumni|Comments Off on Yusuke Hara

About the National University of Singapore

About NUSA leading global university centred in Asia, NUS is Singapore's flagship university, offering a global approach to education and research with a focus on Asian perspectives and expertise.

About the Mechanobiology Institute, National University of Singapore

About MBIOne of four Research Centres of Excellence at NUS, MBI is working to identify, measure and describe how the forces for motility and morphogenesis are expressed at the molecular, cellular and tissue level.
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