Toyama Group

Yusuke HARA

Alumni, Mechanobiology Institute, National University of Singapore

mbiyusu@nus.edu.sg
Level 10 T-Lab
National University of Singapore
5A Engineering Drive 1
Singapore 117411

An early Christmas dinner to celebrate Chan Lab’s accomplishments in 2023!

As the year draws to a close, the Chan Lab celebrated the achievements and contributions by everyone (including many new faces!) in 2023 with an early Christmas dinner, and to thank them for their hard work this busy year. The Lab looks forward to more wonderful things to come in 2024!

By Shu Chian Tay|Dec 4th, 2023|Categories: Chan Lab News|Comments Off on An early Christmas dinner to celebrate Chan Lab’s accomplishments in 2023!

How does the cytoskeleton transmit mechanical forces?

How does the cytoskeleton transmit mechanical forces?It is clear that mechanical forces and structural cues influence cell behavior by regulating signal processes. These signals go on to alter gene expression and reorganize the cytoskeleton and [...]

By Management|Nov 30th, 2023|Categories: About Mechanobiology, MBInfo|Comments Off on How does the cytoskeleton transmit mechanical forces?

What types of forces do cells encounter?

What types of forces do cells encounter?Cells and subcellular structures experience forces from a variety of sources. In general, forces are developed from within the cell via the cytoskeleton (endogenous forces) or come from outside [...]

By Management|Nov 30th, 2023|Categories: About Mechanobiology, MBInfo|Comments Off on What types of forces do cells encounter?

Is Mechanosensing an Active Process?

Is Mechanosensing an Active Process?Types of MechanosensingWhen a cell periodically tests its external environment, a mechanical signal is converted to a chemical signal across the cell membrane. Adhesion receptors located on the external cell membrane [...]

By Management|Nov 30th, 2023|Categories: About Mechanobiology, MBInfo|Comments Off on Is Mechanosensing an Active Process?

How is Energy Transferred Across the Cellular System?

How is Energy Transferred Across the Cellular System?Cellular systems function at a nanometer level and use a highly dynamic set of components. Both of these factors act as primary constraints that prevent the generation of [...]

By Management|Nov 30th, 2023|Categories: About Mechanobiology, MBInfo|Comments Off on How is Energy Transferred Across the Cellular System?

Yusuke Hara

Alumni

Principal Investigator

Yusuke Toyama

Research Interests

Mechanotransduction in Tissues

Recent Publications

  1. Sun Z, Amourda C, Shagirov M, Hara Y, Saunders TE, and Toyama Y. Author Correction: Basolateral protrusion and apical contraction cooperatively drive Drosophila germ-band extension. Nat. Cell Biol. 2018;. [PMID: 29507405]
  2. Hara Y. Contraction and elongation: Mechanics underlying cell boundary deformations in epithelial tissue. Dev. Growth Differ. 2017;. [PMID: 28573735]
  3. Ding WY, Ong HT, Hara Y, Wongsantichon J, Toyama Y, Robinson RC, Nédélec F, and Zaidel-Bar R. Plastin increases cortical connectivity to facilitate robust polarization and timely cytokinesis. J. Cell Biol. 2017;. [PMID: 28400443]
  4. Sun Z, Amourda C, Shagirov M, Hara Y, Saunders TE, and Toyama Y. Basolateral protrusion and apical contraction cooperatively drive Drosophila germ-band extension. Nat. Cell Biol. 2017;. [PMID: 28346438]
  5. Bertocchi C, Wang Y, Ravasio A, Hara Y, Wu Y, Sailov T, Baird MA, Davidson MW, Zaidel-Bar R, Toyama Y, Ladoux B, Mege R, and Kanchanawong P. Nanoscale architecture of cadherin-based cell adhesions. Nat. Cell Biol. 2016;. [PMID: 27992406]
  6. Hara Y, Shagirov M, and Toyama Y. Cell Boundary Elongation by Non-autonomous Contractility in Cell Oscillation. Curr. Biol. 2016; 26(17):2388-96. [PMID: 27524484]
By Management|2018-02-20T13:14:57+08:00Apr 20th, 2017|Categories: Alumni, Toyama Alumni|Comments Off on Yusuke Hara

About the National University of Singapore

About NUSA leading global university centred in Asia, NUS is Singapore's flagship university, offering a global approach to education and research with a focus on Asian perspectives and expertise.

About the Mechanobiology Institute, National University of Singapore

About MBIOne of four Research Centres of Excellence at NUS, MBI is working to identify, measure and describe how the forces for motility and morphogenesis are expressed at the molecular, cellular and tissue level.
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