Is Mechanosensing an Active Process?Types of MechanosensingWhen a cell periodically tests its external environment, a mechanical signal is converted to a chemical signal across the cell membrane. Adhesion receptors located on the external cell membrane [...]

How does the cytoskeleton transmit mechanical forces?It is clear that mechanical forces and structural cues influence cell behavior by regulating signal processes. These signals go on to alter gene expression and reorganize the cytoskeleton and [...]

How is Energy Transferred Across the Cellular System?Cellular systems function at a nanometer level and use a highly dynamic set of components. Both of these factors act as primary constraints that prevent the generation of [...]

Protein LocalizationIn order for subcellular processes to be carried out within defined compartments or cellular regions, mechanisms must exist to ensure the required protein components are present at the sites and at an adequate concentration. [...]

Spatiotemporal control of DNA, RNA, protein and lipid synthesisIn eukaryotes, synthesis of DNA, RNA, proteins and lipids is performed in a spatiotemporal manner. Each molecule is produced within specialized organelles or compartments with strict regulatory [...]

The CellCells are the basic units of life; small machines that facilitate and sustain every process within a living organism. Muscle cells contract to maintain a heartbeat and allow us to move, neurons form networks [...]