Wu Min Group

Yang YANG

Alumni, Mechanobiology Institute, National University of Singapore

a0095425@u.nus.edu
Level 10 T-Lab
National University of Singapore
5A Engineering Drive 1
Singapore 117411

Biomaterial shows how ageing in the heart could be reversed

A new lab-grown material has revealed that some of the effects of ageing in the heart may be slowed and even reversed. The discovery could open the door to therapies that rejuvenate the heart by changing its cellular environment, rather than focusing on the heart cells themselves.Learn more

By Sung Eun|Jun 18th, 2025|Categories: Science Features|Comments Off on Biomaterial shows how ageing in the heart could be reversed
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Rejuvenation of aged egg cells

MBI researchers collaborated with NUS Bia-Echo Asia Centre for Reproductive Longevity and Equality, based at the NUS Yong Loo Lin School of Medicine, to develop an innovative technique to significantly enhance the reproductive potential of aged oocytes, or immature egg cells, potentially paving the way for better outcomes of assisted reproductive technologies, such as in-vitro fertilisation (IVF), for older females. Learn more

By Andrew Wong|Jun 9th, 2025|Categories: Science Features|Comments Off on Rejuvenation of aged egg cells
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Yang Yang

Alumni

Principal Investigator

Wu Min

Research Interests

The Cell-Matrix and Cell-Cell Mechanotransduction Group

Recent Publications

  1. Xiong D, Tong C, Fung SYS, McClellan S, Yang Y, Yong J, and Wu M. STIM1 and endoplasmic reticulum-plasma membrane contact sites oscillate independently of calcium-induced calcium release. Open Biol 2026; 16(3). [PMID: 41844235]
  2. De Leoz MLA, Duewer DL, Fung A, Liu L, Yau HK, Potter O, Staples GO, Furuki K, Frenkel R, Hu Y, Sosic Z, Zhang P, Altmann F, Grunwald-Grube C, Shao C, Zaia J, Evers W, Pengelley S, Suckau D, Wiechmann A, Resemann A, Jabs W, Beck A, Froehlich JW, Huang C, Li Y, Liu Y, Sun S, Wang Y, Seo Y, An HJ, Reichardt N, Ruiz JE, Archer-Hartmann S, Azadi P, Bell L, Lakos Z, An Y, Cipollo JF, Pucic-Bakovic M, Štambuk J, Lauc G, Li X, Wang PG, Bock A, Hennig R, Rapp E, Creskey M, Cyr TD, Nakano M, Sugiyama T, Leung PA, Link-Lenczowski P, Jaworek J, Yang S, Zhang H, Kelly T, Klapoetke S, Cao R, Kim JY, Lee HK, Lee JY, Yoo JS, Kim S, Suh S, de Haan N, Falck D, Lageveen-Kammeijer GSM, Wuhrer M, Emery RJ, Kozak RP, Liew LP, Royle L, Urbanowicz PA, Packer NH, Song X, Everest-Dass A, Lattová E, Cajic S, Alagesan K, Kolarich D, Kasali T, Lindo V, Chen Y, Goswami K, Gau B, Amunugama R, Jones R, Stroop CJM, Kato K, Yagi H, Kondo S, Yuen CT, Harazono A, Shi X, Magnelli PE, Kasper BT, Mahal L, Harvey DJ, O'Flaherty R, Rudd PM, Saldova R, Hecht ES, Muddiman DC, Kang J, Bhoskar P, Menard D, Saati A, Merle C, Mast S, Tep S, Truong J, Nishikaze T, Sekiya S, Shafer A, Funaoka S, Toyoda M, de Vreugd P, Caron C, Pradhan P, Tan NC, Mechref Y, Patil S, Rohrer JS, Chakrabarti R, Dadke D, Lahori M, Zou C, Cairo C, Reiz B, Whittal RM, Lebrilla CB, Wu L, Guttman A, Szigeti M, Kremkow BG, Lee KH, Sihlbom C, Adamczyk B, Jin C, Karlsson NG, Örnros J, Larson G, Nilsson J, Meyer B, Wiegandt A, Komatsu E, Perreault H, Bodnar ED, Said N, Francois Y, Leize-Wagner E, Maier S, Zeck A, Heck AJR, Yang Y, Haselberg R, Yu YQ, Alley W, Leone JW, Yuan H, and Stein SE. NIST Interlaboratory Study on Glycosylation Analysis of Monoclonal Antibodies: Comparison of Results from Diverse Analytical Methods. Mol Cell Proteomics 2019; 19(1):11-30. [PMID: 31591262]
  3. Chen Y, Yong J, Martínez-Sánchez A, Yang Y, Wu Y, De Camilli P, Fernández-Busnadiego R, and Wu M. Dynamic instability of clathrin assembly provides proofreading control for endocytosis. J. Cell Biol. 2019;. [PMID: 31451612]
  4. Yang Y, and Wu M. Rhythmicity and waves in the cortex of single cells. Philos. Trans. R. Soc. Lond., B, Biol. Sci. 2018; 373(1747). [PMID: 29632268]
  5. Yang Y, Xiong D, Pipathsouk A, Weiner OD, and Wu M. Clathrin Assembly Defines the Onset and Geometry of Cortical Patterning. Dev. Cell 2017; 43(4):507-521.e4. [PMID: 29161594]
  6. Xiao S, Tong C, Yang Y, and Wu M. Mitotic Cortical Waves Predict Future Division Sites by Encoding Positional and Size Information. Dev. Cell 2017; 43(4):493-506.e3. [PMID: 29161593]

By Management|2018-03-21T09:53:35+08:00Apr 19th, 2017|Categories: Alumni|Comments Off on Yang Yang

MBI

Decoding the living machine

At the Mechanobiology Institute, National University of Singapore, our goal is to develop the world’s leading centre for mechanobiology research and education. Our research aims to interrogate biological systems from a physical and mechanical perspective at the molecular, cellular, and tissue level, with the eventual goal to leverage basic science discoveries in mechanobiology into biomedical innovations.

MBI gratefully acknowledges support from:

National University of Singapore

National Research Foundation Singapore

Ministry of Education Singapore

Contact us

Mechanobiology Institute (MBI)

National University of Singapore
    T-Lab, #10-01
    5A Engineering Drive 1
    Singapore 117411

Campus map

  mbi.nus.edu.sg
  mbi@nus.edu.sg
  +65 6601 5424

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About the National University of Singapore

About NUSA leading global university centred in Asia, NUS is Singapore's flagship university, offering a global approach to education and research with a focus on Asian perspectives and expertise.

About the Mechanobiology Institute, National University of Singapore

About MBIOne of four Research Centres of Excellence at NUS, MBI is working to identify, measure and describe how the forces for motility and morphogenesis are expressed at the molecular, cellular and tissue level.
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