Shivashankar Group

WANG Yejun

Alumni, Mechanobiology Institute, National University of Singapore

mbiwye@nus.edu.sg
Level 10 T-Lab
National University of Singapore
5A Engineering Drive 1
Singapore 117411

Seeking Postdoctoral Research Fellow (Biomaterials and Mechanobiology) in the group of Asst. Prof. Jennifer Young at the Mechanobiology Institute, NUS

The Mechanobiology Institute, NUS, seeks to recruit a Postdoctoral Research Fellow (Biomaterials and Mechanobiology) in the group of Asst. Prof. Jennifer Young.

By Wen Ying Lois Faith|Mar 19th, 2026|Categories: Job Archives|Comments Off on Seeking Postdoctoral Research Fellow (Biomaterials and Mechanobiology) in the group of Asst. Prof. Jennifer Young at the Mechanobiology Institute, NUS

Seeking Postdoctoral Research Fellow (Spatial Omics) in the group of Asst. Prof. Jennifer Young at the Mechanobiology Institute, NUS

The Mechanobiology Institute, NUS, seeks to recruit a Postdoctoral Research Fellow (Spatial Omics) in the group of Asst. Prof. Jennifer Young.

By Wen Ying Lois Faith|Mar 19th, 2026|Categories: Jobs|Comments Off on Seeking Postdoctoral Research Fellow (Spatial Omics) in the group of Asst. Prof. Jennifer Young at the Mechanobiology Institute, NUS

She is a Scientist: Confidence Formed by Curiosity Over Time

February 11th celebrates The International Day of Women and Girls in Science to promote full, equal access and participation in STEM fields. MBI talks to two of our posdoctoral research fellows about their career as a woman in science.

By Yee Shu Brenda|Feb 11th, 2026|Categories: Chan Lab, Kanchanawong Lab, MBInsights, News, People of MBI|Comments Off on She is a Scientist: Confidence Formed by Curiosity Over Time

Wang Yejun

Alumni

Principal Investigator

GV Shivashankar

Research Interests

Molecular Mechanisms of Mechanobiology

I decided to switch into the world of biology after I received my BS in chemistry from Zhejiang University. With the interest in things happening inside nucleus, I joined Prof. Shiva’s lab as a graduate student, to study the role of external mechanical signals on gene regulation in eukaryotic cells. During my first one and a half years I developed a method to visualize active transcription sites on open chromatin spreads using super-resolution microscopy. Presently I’m studying the role of cell geometric constraints on 3D organization of chromosomes by using multiple techniques such as fluorescence in situ hybridization (FISH), confocal imaging, and super-resolution imaging.

Recent Publications

  1. Wang Y, Li X, Xia R, Wan Y, Lu J, Zhao Z, Zhang W, Wang Q, Saunders TE, and Yin J. Hedgehog-driven adaxial cell constriction patterns slow muscle fate and somite boundary remodeling in the presomitic mesoderm. Cell Rep 2026; 45(5):117319. [PMID: 42065961]
  2. Yang J, Guan Z, Zeng D, Qin Y, Zhao C, Wang S, Wu Q, Wang Q, Li H, Wu J, Huang H, Wang Y, Wu E, Thalmann NM, Lim CT, Wong TY, Jia W, Li H, Fregni F, and Sheng B. Extended reality in clinical neurology: From interdisciplinary innovations to clinical practice. Cell Rep Med 2026;:102696. [PMID: 41903546]
  3. Yang B, Li B, Zhu Y, Zhao M, Cheng Y, Zhao X, En-Jie DT, Wang Y, Zhang M, Tang X, Jin S, Sun Y, Zhang X, Xue B, Yan J, Wu G, Lin Z, Luo M, Yu H, Zhang L, Chen X, and Ni Q. Rational design of rigid mRNA folding architecture to enhance intracellular processing and protein production. Nat Nanotechnol 2026;. [PMID: 41772191]
  4. Liu X, Liu J, Wang Y, Yao M, Baker KB, Klapholz B, Brown NH, Goult BT, and Yan J. The mechanical response of vinculin. Sci Adv 2025; 11(44):eady6949. [PMID: 41171905]
  5. Wang Y, Zhang Y, Yu M, Xiu P, Jia Y, Chen H, Le S, Qian J, and Yan J. Salt-bridge mediated cooperativity and mechanical stabilization of tandem spectrin repeats. Nanoscale Horiz 2025;. [PMID: 40492359]
  6. Wang W, Huang Z, Wang Y, Li H, and Kanchanawong P. Vortex Interference Enables Optimal 3D Interferometric Nanoscopy. Phys Rev Lett 2025; 134(7):073802. [PMID: 40053988]
  7. Wang Y, Wang Y, Zhu Y, Yu P, Zhou F, Zhang A, Gu Y, Jin R, Li J, Zheng F, Yu A, Ye D, Xu Y, Liu Y, Saw TB, Hu G, Lim CT, and Yu F. Angiomotin cleavage promotes leader formation and collective cell migration. Dev Cell 2024;. [PMID: 39389053]
  8. Zhang Y, Du J, Liu X, Shang F, Deng Y, Ye J, Wang Y, Yan J, Chen H, Yu M, and Le S. Multi-domain interaction mediated strength-building in human α-actinin dimers unveiled by direct single-molecule quantification. Nat Commun 2024; 15(1):6151. [PMID: 39034324]
  9. Morales-Camilo N, Liu J, Ramírez MJ, Canales-Salgado P, Alegría JJ, Liu X, Ong HT, Barrera NP, Fierro A, Toyama Y, Goult BT, Wang Y, Meng Y, Nishimura R, Fong-Ngern K, Low CSL, Kanchanawong P, Yan J, Ravasio A, and Bertocchi C. Alternative molecular mechanisms for force transmission at adherens junctions via β-catenin-vinculin interaction. Nat Commun 2024; 15(1):5608. [PMID: 38969637]
  10. Zhang X, Ruan L, Wang H, Zhu J, Li T, Sun G, Dong Y, Wang Y, Berreby G, Shay A, Chen R, Ramachandran S, Dawson VL, Dawson TM, and Li R. Enhancing mitochondrial proteolysis alleviates alpha-synuclein-mediated cellular toxicity. NPJ Parkinsons Dis 2024; 10(1):120. [PMID: 38906862]
By Management|2018-03-05T16:22:36+08:00Mar 23rd, 2017|Categories: Alumni|Comments Off on Wang Yejun

About the National University of Singapore

About NUSA leading global university centred in Asia, NUS is Singapore's flagship university, offering a global approach to education and research with a focus on Asian perspectives and expertise.

About the Mechanobiology Institute, National University of Singapore

About MBIOne of four Research Centres of Excellence at NUS, MBI is working to identify, measure and describe how the forces for motility and morphogenesis are expressed at the molecular, cellular and tissue level.
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