Zaidel-Bar Group

The Nano-Heartbuilder: BNIP-2 Influences Mechanosensing in Cardiomyoblast Differentiation

Researchers from the Low Lab at MBI discover a crucial role for the scaffold protein BNIP-2 in orchestrating focal adhesion dynamics during early heart development, offering new insights into heart regeneration strategies.

By Yee Shu Brenda|Aug 12th, 2025|Categories: Featured Research, Low BC Lab, MBInsights, Science Features|Comments Off on The Nano-Heartbuilder: BNIP-2 Influences Mechanosensing in Cardiomyoblast Differentiation

Shedding Light on Local Microtubule Regulation of Focal Adhesions

Researchers from the Bershadsky Lab at MBI utilized optogenetics to unlock the role of microtubules in regulating focal adhesion disassembly, an important step in cell migration. http://www.mbi.nus.edu.sg/featured-research/microtubules-and-cell-movement-a-closer-look-at-focal-adhesion-disassembly

By Andrew Wong|Aug 8th, 2025|Categories: Bershadsky Lab, Featured Research, MBInsights, Science Features|Comments Off on Shedding Light on Local Microtubule Regulation of Focal Adhesions

A Warm Welcome to the 2025 Ph.D Cohort!

MBI is delighted to welcome the 2025 cohort of Ph.D students. Coming from a rich tapestry of countries – China, Vietnam, Singapore, India and the Philippines – these eleven outstanding individuals bring with them interdisciplinary expertise and fresh perspectives that will enrich MBI’s vibrant research community.

By Yee Shu Brenda|Aug 7th, 2025|Categories: News|Comments Off on A Warm Welcome to the 2025 Ph.D Cohort!

Ding Wei Yung

Alumni

Principal Investigator

Ronen Zaidel-Bar

Research Interests

Cell-Matrix and Cell-Cell Mechanotransduction, Molecular Mechanisms of Mechanobiology

Wei Yung’s interest lies in understanding the sophistication of cells as robust machines. Using C. elegans, a 1mm nematode, as a model system, he investigates the cellular machinery underlying newly fertilized zygotes that drives critical force-dependent processes such as polarization and cytokinesis.

Biography

Wei Yung completed his Bachelor’s degree in Bioengineering (Second Class Upper) from the National University of Singapore in 2012. In his honors dissertation under the co-supervision of Professor James Goh and Professor Wong Hee Kit, he optimized the conditions required for the construction of interbody spinal fusion device using primary adipose stem cells seeded in a biodegradable polycaprolactone/tricalcium sulphate (PCL/TCP) scaffold. The work was presented in the Bioengineering Showcase 2012 and he was awarded the Best Poster Award. After he was enrolled in the Mechanobiology Graduate Program, he joined Dr. Zaidel-Bar’s Cell Adhesion and Morphogenesis Lab and is currently searching for novel genes involved in regulating C. elegans early embryogenesis.

By Management|2019-01-09T13:14:35+08:00Jan 1st, 2013|Categories: Alumni|Comments Off on Ding Wei Yung

About the National University of Singapore

About NUSA leading global university centred in Asia, NUS is Singapore's flagship university, offering a global approach to education and research with a focus on Asian perspectives and expertise.

About the Mechanobiology Institute, National University of Singapore

About MBIOne of four Research Centres of Excellence at NUS, MBI is working to identify, measure and describe how the forces for motility and morphogenesis are expressed at the molecular, cellular and tissue level.
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