Myosin motors show their muscle
How cells generate high forces for testing the softness of their environment
Chloe May Simpson
Alumni, Sheetz Lab
Aaron Joseph Farrugia
Senior Research Fellow, Bershadsky Lab
Geetika Sahni
Senior Research Fellow, Viasnoff Group
The guiding hands (and feet)
Focal adhesions in embryonic stem cells
MBI Senior Research Fellow Rishita Changede wins Best Presentation at TOPIM
MBI Senior Research Fellow Rishita Changede wins the Best Presentation award at the TOPIM Winter Conference 2019, for her presentation on the role of integrin nanoclusters as the basis for the formation of cell-matrix adhesions that aid in sensing the mechanical properties, such as rigidity, of the underlying tissue.
Ding Wei Yung
Alumni
Principal Investigator
Research Interests
Cell-Matrix and Cell-Cell Mechanotransduction, Molecular Mechanisms of Mechanobiology
Wei Yung’s interest lies in understanding the sophistication of cells as robust machines. Using C. elegans, a 1mm nematode, as a model system, he investigates the cellular machinery underlying newly fertilized zygotes that drives critical force-dependent processes such as polarization and cytokinesis.
Biography
Wei Yung completed his Bachelor’s degree in Bioengineering (Second Class Upper) from the National University of Singapore in 2012. In his honors dissertation under the co-supervision of Professor James Goh and Professor Wong Hee Kit, he optimized the conditions required for the construction of interbody spinal fusion device using primary adipose stem cells seeded in a biodegradable polycaprolactone/tricalcium sulphate (PCL/TCP) scaffold. The work was presented in the Bioengineering Showcase 2012 and he was awarded the Best Poster Award. After he was enrolled in the Mechanobiology Graduate Program, he joined Dr. Zaidel-Bar’s Cell Adhesion and Morphogenesis Lab and is currently searching for novel genes involved in regulating C. elegans early embryogenesis.
