WU Min
Collaborator, Mechanobiology Institute, National University of Singapore
dbswum@nus.edu.sg
+65 6601 2310
CBIS Blk S1A, Level 2 Lee Wee Kheng Bldg
National University of Singapore
14 Science Drive 4
Singapore 117557
Laboratory website
Wu Lab Deconstructing the Endocytic Machinery
Research Program
The Cell-Matrix and Cell-Cell Mechanotransduction Group
Affiliations
Department of Biological Sciences, National University of Singapore
MBI-MPG Conference 2025: Mechanobiology in Space and Time.
The MBI-MPG Conference 2025 was held from 9-12th September at the Mechanobiology Institute, National University of Singapore.
Seeking Postdoctoral Fellow in Asst. Prof. Natalie Dye’s Laboratory at the Mechanobiology Institute, NUS
We are seeking to recruit a Postdoctoral Research Fellow in the Dye Laboratory at the Mechanobiology Institute, NUS.
Dr. Jennifer Young Awarded Robert Brown Promising Researcher Award for MOE AcRF Tier 2 Grant
Dr. Jennifer Young received the Robert Brown Promising Researcher Award for her MOE AcRF Tier 2 Grant
Prof Lim Chwee Teck received the 2025 President’s Science Award
Prof. Lim Chwee Teck was awarded the 2025 President’s Science Award (PSA) for his pioneering contributions to cancer research through innovative mechanobiology approaches, successfully bridging engineering, biological sciences and medicine to foster a deeper understanding of cancer metastasis.
Tumor-on-a-chip Shows How Microenvironment Architecture Affects Liver Cancer Therapies
Researchers from the Pavesi Group at the Mechanobiology Institute, NUS develops in vitro models of liver tumors to study how the presence of vasculature networks affect cancer therapies.
Wu Min
Collaborator
Research Areas
Endocytosis, Membrane traffic, Curvature, Actin cytoskeleton, Mechanotransduction
Research Interests
Dr Wu is interested in elucidating the principles underlying the organization and dynamics of the subcellular membrane compartments. Specifically her lab investigates how biological membranes are shaped through collective protein-lipid interactions and how geometry of the membrane compartment is coupled to cellular functions. The Wu Lab uses a combination of cell biological, biophysical and biochemical approaches to address these questions.
Biography
Dr Wu Min graduated from Peking University in China and received her bachelor degree in Chemistry. She did her graduate studies at Cornell University with Dr Barbara Baird, where she initiated the use of patterned lipid bilayers as antigen-presenting platforms and studied immune cell activation and signal transduction. During her post-doctoral research in the laboratory of Dr Pietro De Camilli at Yale School of Medicine, she focused on the molecular mechanisms of endocytosis. In 2011, she was awarded the NRF fellowship, joining CBIS/MBI in the fall.
Education
PhD Cornell University
Recent Publications
- Xiong D, Tong C, Fung SYS, McClellan S, Yang Y, Yong J, and Wu M. STIM1 and endoplasmic reticulum-plasma membrane contact sites oscillate independently of calcium-induced calcium release. Open Biol 2026; 16(3). [PMID: 41844235]
- Chua XL, Tong CS, Su M, Xǔ XJ, Xiao S, Wu X, and Wu M. Competition and synergy of Arp2/3 and formins in nucleating actin waves. Cell Rep 2024; 43(7):114423. [PMID: 38968072]
- Tong CS, Su M, Sun H, Chua XL, Xiong D, Guo S, Raj R, Ong NWP, Lee AG, Miao Y, and Wu M. Collective dynamics of actin and microtubule and its crosstalk mediated by FHDC1. Front Cell Dev Biol 2024; 11:1261117. [PMID: 38567385]
- Le Chua X, Tong CS, Xǔ XJ, Su M, Xiao S, Wu X, and Wu M. Competition and Synergy of Arp2/3 and Formins in Nucleating Actin Waves. bioRxiv 2023;. [PMID: 37745345]
- Su M, Zhuang Y, Miao X, Zeng Y, Gao W, Zhao W, and Wu M. Comparative Study of Curvature Sensing Mediated by F-BAR and an Intrinsically Disordered Region of FBP17. iScience 2020; 23(11):101712. [PMID: 33205024]
- Chen Y, Yong J, Martínez-Sánchez A, Yang Y, Wu Y, De Camilli P, Fernández-Busnadiego R, and Wu M. Dynamic instability of clathrin assembly provides proofreading control for endocytosis. J. Cell Biol. 2019;. [PMID: 31451612]
- . https://www.ncbi.nlm.nih.gov/pubmed/31390543
- Yong J, Chen Y, and Wu M. Real-Time Monitoring of Clathrin Assembly Kinetics in a Reconstituted System. Methods Mol. Biol. 2018; 1847:177-187. [PMID: 30129017]
- Yang Y, and Wu M. Rhythmicity and waves in the cortex of single cells. Philos. Trans. R. Soc. Lond., B, Biol. Sci. 2018; 373(1747). [PMID: 29632268]
- McPherson PS, and Wu M. Light, space, and time in cancer signaling. Mol. Biol. Cell 2018; 29(6):688. [PMID: 29535172]
Lab Members
Pawan Kumar Mishra
Research Fellow, Hirashima Group
Arceo Alaine Vien Villanueva
Research Assistant, Dye & Michelot Group
Xixun Lu
SPS Intern, Chan Group
Hannah Fung
Research Fellow, Li Group
Hatice Zohra Michèle Holuigue
Research Fellow, Young Group
Seeking Research Assistant in the lab of Dr. Anne Beghin at the Mechanobiology Institute, NUS
We are seeking a Research Assistant to join the lab of Dr. Anne Beghin at the Mechanobiology Institute, NUS
Zheng Kexiao
Research Associate, Yu Group
Derek Yuen Yee Jun
Research Assistant, Bershadsky Group
Lab Meeting with the Chan Lab – the Node
The Chan Lab sits down with the Node for to chat about lab life (read here)!
Defining the pattern of cell death and replacement
Researchers from the Toyama Lab at MBI reveal how mechanical factors control apoptosis and cell replacement. https://www.mbi.nus.edu.sg/featured-research/defining-the-pattern-of-cell-death-and-replacement
The Chan lab celebrates two new papers!
Congratulations to the teams! (Read the publication here and the preprint here)
Seeking Research Associate in Molecular and Cell Biology in the Kanchanawong Lab at the Mechanobiology Institute, NUS
We are seeking a Research Associate in Molecular and Cell Biology to join the Kanchanawong at the Mechanobiology Institute, NUS
