In a study published in the Journal of Cell Science, led by Ryosuke Nishimura at the Mechanobiology Institute, NUS, researchers developed an optogenetic tool to precisely manipulate talin’s structure and observe the resulting cellular behavior.
Researchers from the Chan Lab at MBI demonstrate the importance of compressive stress exhibited by theca cells in healthy follicle maturation and surrounding support cells, suggesting a new perspective in understanding infertility.
Researchers from the Chan Lab at MBI develop a a novel method called quantitative micro-elastography to create detailed 3D maps of ovarian stiffness in mice—revealing crucial insights that could lead to new infertility treatments.
Researchers from the Pavesi Group at the Mechanobiology Institute, NUS develops in vitro models of liver tumors to study how the presence of vasculature networks affect cancer therapies.
Researchers from the Kanchanawong Lab at the Mechanobiology Institute, NUS makes cutting-edge 3D nanoscopy more accessible to researchers without elaborate optical engineering.
Researchers from the Kanchanawong Lab at the Mechanobiology Institute, NUS discover a marker of ground-state pluripotent stem cells and what governs it.
Researchers from the Holle Lab at the Mechanobiology Institute, NUS discover that migration through confined spaces causes lasting nuclear changes in stem cells, biasing them toward bone formation.
Researchers from the Li Lab discover how α5-integrin–FN interactions preserve dermal integrity, offering new insights for antiaging strategies targeting ECM organization and fibroblast function.
Researchers from the Soft Nano-Biomaterials Lab at MBI developed a material system to enable precise investigation into how individual ECM properties affect cultured heart cells.
Researchers from the Toyama Lab at MBI reveal how mechanical factors control apoptosis and cell replacement.
Researchers from the Beghin Lab at the Mechanobiology Institute, NUS combine DeepStar3D algorithm and 3DCellScope interface to develop an experimental tool for real-time interaction with cell data.
Researchers from the Low Lab at MBI discover a crucial role for the scaffold protein BNIP-2 in orchestrating focal adhesion dynamics during early heart development, offering new insights into heart regeneration strategies.
A leading global university centred in Asia, NUS is Singapore's flagship university, offering a global approach to education and research with a focus on Asian perspectives and expertise.
One of four Research Centres of Excellence at NUS, MBI is working to identify, measure and describe how the forces for motility and morphogenesis are expressed at the molecular, cellular and tissue level.