She is a Scientist: Confidence Formed by Curiosity Over Time

February 11th celebrates The International Day of Women and Girls in Science to promote full, equal access and participation in STEM fields. MBI talks to two of our posdoctoral research fellows about their career as a woman in science.

By Brenda Lau Yee Shu|2026-02-11T15:52:20+08:00Feb 11th, 2026|Categories: Chan Lab, Kanchanawong Lab, MBInsights, News, People of MBI|Comments Off on She is a Scientist: Confidence Formed by Curiosity Over Time

She is Becoming: Curiosity, Comparison and the Making of a Scientist

February 11th celebrates The International Day of Women and Girls in Science to promote full, equal access and participation in STEM fields. MBI talks to two of our PhD students about their journey in becoming a scientist as women.

By Brenda Lau Yee Shu|2026-02-13T14:15:47+08:00Feb 11th, 2026|Categories: Dye Lab, Hirashima Lab, MBInsights, News, People of MBI|Comments Off on She is Becoming: Curiosity, Comparison and the Making of a Scientist

How Structural Imbalance Drives Inflammatory Signaling in Senescent Cells

In a study published in Molecular Biology of the Cell led by Celestine Ho at the Mechanobiology Institute, NUS, researchers discover that HIF-1α-activation in SASP is a defining feature of the SASP induced by diverse stressors, acting independently of micronuclei generation and cGAS/STING activation.

By Brenda Lau Yee Shu|2026-02-06T11:59:09+08:00Feb 6th, 2026|Categories: Low BC Lab, Low BC Lab News, MBInsights, Science Features|Comments Off on How Structural Imbalance Drives Inflammatory Signaling in Senescent Cells

MBI Hosts Students from Sakura High School!

MBI hosted students from Sakura High School, Chiba, Japan on 22nd January 2026 for an outreach session designed to spark curiosity about mechanobiology and research careers.

By Brenda Lau Yee Shu|2026-01-26T11:31:38+08:00Jan 26th, 2026|Categories: MBInsights, News|Comments Off on MBI Hosts Students from Sakura High School!

Violet vs. Blue: Controlling Mechanotransduction with a Single-protein Light Switch

In a study published in the Journal of Cell Science, led by Ryosuke Nishimura at the Mechanobiology Institute, NUS, researchers developed an optogenetic tool to precisely manipulate talin’s structure and observe the resulting cellular behavior.

By Brenda Lau Yee Shu|2026-01-07T11:01:51+08:00Jan 7th, 2026|Categories: Kanchanawong Lab, MBInsights, Science Features|Comments Off on Violet vs. Blue: Controlling Mechanotransduction with a Single-protein Light Switch

EASMB Symposium 2025 Showcases Global Participation and Relevance

The East Asian Single-Molecule Biophysics Symposium 2025 (EASMB2025) held from 24 to 26 November at the Ngee Ann Kongsi Auditorium in the Education Resource Centre, UTown, National University of Singapore showcased global participation and relevance.

By Brenda Lau Yee Shu|2025-12-01T11:46:07+08:00Dec 1st, 2025|Categories: MBInsights, News|Comments Off on EASMB Symposium 2025 Showcases Global Participation and Relevance

The Pressure That Shapes Life: Mechanical Forces Behind Egg Maturation

Researchers from the Chan Lab at MBI demonstrate the importance of compressive stress exhibited by theca cells in healthy follicle maturation and surrounding support cells, suggesting a new perspective in understanding infertility.

By Brenda Lau Yee Shu|2025-10-31T18:23:43+08:00Oct 31st, 2025|Categories: Chan Lab News, MBInsights, Science Features|Comments Off on The Pressure That Shapes Life: Mechanical Forces Behind Egg Maturation

Quantitative Micro-Elastography: New Imaging Tool Uncovers Age-Dependent Mechanical Changes in Ovarian Tissue

Researchers from the Chan Lab at MBI develop a a novel method called quantitative micro-elastography to create detailed 3D maps of ovarian stiffness in mice—revealing crucial insights that could lead to new infertility treatments.

By Brenda Lau Yee Shu|2025-10-31T10:43:54+08:00Oct 14th, 2025|Categories: Chan Lab News, MBInsights, Science Features|Comments Off on Quantitative Micro-Elastography: New Imaging Tool Uncovers Age-Dependent Mechanical Changes in Ovarian Tissue

About the National University of Singapore

About NUSA leading global university centred in Asia, NUS is Singapore's flagship university, offering a global approach to education and research with a focus on Asian perspectives and expertise.

About the Mechanobiology Institute, National University of Singapore

About MBIOne of four Research Centres of Excellence at NUS, MBI is working to identify, measure and describe how the forces for motility and morphogenesis are expressed at the molecular, cellular and tissue level.
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