Saunders Group

The mechanical editor

A recent study led by Dr. Shaobo Zhang and MBI Principal Investigator Associate Professor Timothy Saunders describes how periodic filopodial retraction caused by the contractile activity of transient Myosin II clusters at the cell leading edge ensures precise matching between primitive heart cells during heart development in Drosophila embryos. Learn more

By Management|Oct 12th, 2020|Categories: Featured Research, Science Features|Comments Off on The mechanical editor

A molecular brake

Recent study led by MBI Research Fellows Pan Meng and Ti Weng Chew and Principal Investigator Associate Professor Low Boon Chuan has revealed a role for BNIP-2 protein in scaffolding GEF-H1 and RhoA, following microtubule disassembly, and has described how this scaffolding is important for RhoA-dependent regulation of cell migration. Learn more

By Management|Oct 2nd, 2020|Categories: Featured Research, Low BC Lab, Science Features|Comments Off on A molecular brake

Zhang Shaobo

Alumni

Principal Investigator

Timothy Saunders

Research Interests

Mechanotransduction in Tissues Group

I joined the Saunders group on an internship as part of my Final Year Project during undergraduate study. The internship has been an amazing experience and helped me make up my mind to continue my journey in the mechanics of development – an exciting field which requires the integration of biology, physics, computer science and engineering.

My background during undergraduate study is in Bioinformatics (at Shanghai Jiao Tong University), and this has prepared me well for future exploration. I hope to use quantitative analysis techniques to study robust and precise cell matching processes. By applying embryonic Drosophila heart formation as a simplified matching system, I am looking forward to deciphering the deeper mechanisms of the cell targeting process about how cells find their partners in a complicated environment.

By Management|2020-10-21T10:04:29+08:00Apr 11th, 2017|Categories: Alumni|Comments Off on Zhang Shaobo

About the National University of Singapore

About NUSA leading global university centred in Asia, NUS is Singapore's flagship university, offering a global approach to education and research with a focus on Asian perspectives and expertise.

About the Mechanobiology Institute, National University of Singapore

About MBIOne of four Research Centres of Excellence at NUS, MBI is working to identify, measure and describe how the forces for motility and morphogenesis are expressed at the molecular, cellular and tissue level.
Go to Top