Lim Group, Ladoux Group

SAW Thuan Beng

Alumni, Research Associate, Mechanobiology Institute, National University of Singapore

mbistb@nus.edu.sg
Level 9 T-Lab
National University of Singapore
5A Engineering Drive 1
Singapore 117411

Saw Thuan Beng

Alumni, Research Associate

Principal Investigator

CT Lim, Benoit Ladoux

Research Interests

Molecular Mechanisms of Mechanobiology

Recent Publications

  1. Jiang X, Xu P, Feng F, Grenci G, and Saw TB. Revealing Electromechanical Control of Tissue Homeostasis Using a Two-Layer Microfluidic Device. J Vis Exp 2025;(223). [PMID: 41052031]
  2. Wang Y, Wang Y, Zhu Y, Yu P, Zhou F, Zhang A, Gu Y, Jin R, Li J, Zheng F, Yu A, Ye D, Xu Y, Liu Y, Saw TB, Hu G, Lim CT, and Yu F. Angiomotin cleavage promotes leader formation and collective cell migration. Dev Cell 2024;. [PMID: 39389053]
  3. Delanoë-Ayari H, Hiraiwa T, Marcq P, Rieu J, and Saw TB. 2.5D Traction Force Microscopy: Imaging three-dimensional cell forces at interfaces and biological applications. Int J Biochem Cell Biol 2023;:106432. [PMID: 37290687]
  4. . https://www.ncbi.nlm.nih.gov/pubmed/36103541
  5. Balasubramaniam L, Doostmohammadi A, Saw TB, Narayana GHNS, Mueller R, Dang T, Thomas M, Gupta S, Sonam S, Yap AS, Toyama Y, Mège R, Yeomans JM, and Ladoux B. Author Correction: Investigating the nature of active forces in tissues reveals how contractile cells can form extensile monolayers. Nat Mater 2021;. [PMID: 33750921]
  6. Balasubramaniam L, Doostmohammadi A, Saw TB, Narayana GHNS, Mueller R, Dang T, Thomas M, Gupta S, Sonam S, Yap AS, Toyama Y, Mège R, Yeomans JM, and Ladoux B. Investigating the nature of active forces in tissues reveals how contractile cells can form extensile monolayers. Nat Mater 2021;. [PMID: 33603188]
  7. Teo JL, Lim CT, Yap AS, and Saw TB. A Biologist's Guide to Traction Force Microscopy Using Polydimethylsiloxane Substrate for Two-Dimensional Cell Cultures. STAR Protoc 2020; 1(2):100098. [PMID: 33111126]
  8. Chen T, Saw TB, Mège R, and Ladoux B. Mechanical forces in cell monolayers. J. Cell. Sci. 2018; 131(24). [PMID: 30573527]
  9. Saw TB, Xi W, Ladoux B, and Lim CT. Biological Tissues as Active Nematic Liquid Crystals. Adv. Mater. Weinheim 2018;:e1802579. [PMID: 30156334]
  10. Saw TB, Doostmohammadi A, Nier V, Kocgozlu L, Thampi S, Toyama Y, Marcq P, Lim CT, Yeomans JM, and Ladoux B. Topological defects in epithelia govern cell death and extrusion. Nature 2017; 544(7649):212-216. [PMID: 28406198]
By Management|2018-01-22T15:53:47+08:00Apr 25th, 2017|Categories: Alumni|Comments Off on Saw Thuan Beng

MBI

Decoding the living machine

At the Mechanobiology Institute, National University of Singapore, our goal is to develop the world’s leading centre for mechanobiology research and education. Our research aims to interrogate biological systems from a physical and mechanical perspective at the molecular, cellular, and tissue level, with the eventual goal to leverage basic science discoveries in mechanobiology into biomedical innovations.

MBI gratefully acknowledges support from:

National University of Singapore

National Research Foundation Singapore

Ministry of Education Singapore

Contact us

Mechanobiology Institute (MBI)

National University of Singapore
    T-Lab, #10-01
    5A Engineering Drive 1
    Singapore 117411

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  mbi.nus.edu.sg
  mbi@nus.edu.sg
  +65 6601 5424

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About the National University of Singapore

About NUSA leading global university centred in Asia, NUS is Singapore's flagship university, offering a global approach to education and research with a focus on Asian perspectives and expertise.

About the Mechanobiology Institute, National University of Singapore

About MBIOne of four Research Centres of Excellence at NUS, MBI is working to identify, measure and describe how the forces for motility and morphogenesis are expressed at the molecular, cellular and tissue level.
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