FU Chaoyu

Research Assistant, Mechanobiology Institute, National University of Singapore

e0018313@u.nus.edu
Level 10 T-Lab
National University of Singapore
5A Engineering Drive 1
Singapore 117411

Fu Chaoyu

Research Assistant

Principal Investigator

Virgile Viasnoff, Michael Sheetz

Research Interests

Cell-Matrix and Cell-Cell Mechanotransduction

Recent Publications

  1. Wang J, Fu C, Chang S, Stephens C, Li H, Wang D, Fu YC, Green KJ, Yan J, and Yi R. PIEZO1-mediated calcium signaling reinforces mechanical properties of hair follicle stem cells to promote quiescence. Sci Adv 2025; 11(22):eadt2771. [PMID: 40435254]
  2. Arora A, Rizvi MS, Grenci G, Dilasser F, Fu C, Ganguly M, Vaishnavi S, Paramsivam K, Budnar S, Noordstra I, Yap AS, and Viasnoff V. Viscous dissipation in the rupture of cell-cell contacts. Nat Mater 2025;. [PMID: 40355570]
  3. Zhang Y, Chen K, Tang SC, Cai Y, Nambu A, See YX, Fu C, Raju A, Lebeau B, Ling Z, Chan JJ, Tay Y, Mutwil M, Lakshmanan M, Tucker-Kellogg G, Chng WJ, Tenen DG, Osato M, Tergaonkar V, and Fullwood MJ. Super-silencer perturbation by EZH2 and REST inhibition leads to large loss of chromatin interactions and reduction in cancer growth. Nat Struct Mol Biol 2024;. [PMID: 39304765]
  4. Le S, Yu M, Fu C, Heier JA, Martin S, Hardin J, and Yan J. Single-molecule force spectroscopy reveals intra- and intermolecular interactions of Caenorhabditis elegans HMP-1 during mechanotransduction. Proc Natl Acad Sci U S A 2024; 121(37):e2400654121. [PMID: 39236238]
  5. Fu C, Dilasser F, Lin S, Karnat M, Arora A, Rajendiran H, Ong HT, Mui Hoon Brenda N, Phow SW, Hirashima T, Sheetz M, Rupprecht J, Tlili S, and Viasnoff V. Regulation of intercellular viscosity by E-cadherin-dependent phosphorylation of EGFR in collective cell migration. Proc Natl Acad Sci U S A 2024; 121(37):e2405560121. [PMID: 39231206]
  6. Fu C, Huang W, Tang Q, Niu M, Guo S, Langenhan T, Song G, and Yan J. Unveiling Mechanical Activation: GAIN Domain Unfolding and Dissociation in Adhesion GPCRs. Nano Lett 2023;. [PMID: 37831892]
  7. Huang W, Fu C, and Yan J. Single-Cell Quantification of the Mechanical Stability of Cell-Cell Adherens Junction Using Glass Micropipettes. Methods Mol Biol 2023; 2600:267-280. [PMID: 36587103]
  8. Fu C, Arora A, Engl W, Sheetz M, and Viasnoff V. Cooperative regulation of adherens junction expansion through Epidermal Growth Factor Receptor (EGFR) activation. J Cell Sci 2022;. [PMID: 35099018]
  9. Yang Y, Nguyen E, Sankara Narayana GHN, Heuzé M, Fu C, Yu H, Mège R, Ladoux B, and Sheetz MP. Local contractions regulate E-cadherin rigidity sensing. Sci Adv 2022; 8(4):eabk0387. [PMID: 35089785]