What is the epithelial to mesenchymal transition?
What is the epithelial to mesenchymal transition? Epithelial to mesenchymal transition (EMT) is the process whereby epithelial cells are transformed into mesenchymal cells. Epithelial cells form the epithelium tissue which covers the internal and [...]
What is the mesenchymal to epithelial transition?
What is the mesenchymal-epithelial transition? During development, the transitioning of epithelial cells to a mesenchymal lineage is not an irreversible process. Instead, a number of developmental programs are accompanied by a reversal of EMT, [...]
What is hematopoiesis?
What is hematopoiesis? The hematopoietic system, which comprises all the cellular components of the blood, is one of the earliest organ systems to evolve during embryo development. Hematopoietic stem cells (HSCs), which are rare [...]
What is the cellular origin of hematopoietic stem cells?
What is the cellular origin of hematopoietic stem cells? Based on findings from a large number of anatomical, biochemical, and genetic studies carried out over the years, three major theories have been put forth [...]
What are cell-cell adhesions?
What are cell-cell adhesions? Cell-cell signaling refers to inter-cellular communication through the transduction of chemical, mechanical or electrical signals, facilitated by the formation of specialized cell-cell adhesion junctions. There are three main types of [...]
How are cell-cell adhesions regulated?
How are cell-cell adhesions regulated? Introduction to the regulation of cell-cell adhesion The assembly and disassembly of cell-cell junctions, such as adherens junctions (AJ), are regulated by a vast array of factors functioning in [...]
