Sriram MUTHUKUMAR

Research Fellow, Mechanobiology Institute, National University of Singapore

sriramm@nus.edu.sg
Level 9 T-Lab
National University of Singapore
5A Engineering Drive 1
Singapore 117411

Sriram Muthukumar

Research Fellow

Principal Investigator

Andrew Holle

Research Areas

Confinement mechanobiology, stem cell biology, tissue engineering and drug delivery

Qualifications

Master of Technology, PhD

Biography

Sriram Muthukumar earned his B.Tech. in Biotechnology from SRM University, India, followed by an M.Tech. and Ph.D. from the Indian Institute of Technology Kanpur (2015–2023). His doctoral research focused on developing biomimetic scaffolds for tissue engineering, specializing in advanced biofabrication techniques. Currently, he is a researcher at the Mechanobiology Institute, working in Andrew Holle’s group to investigate the role of mechanical confinement in biological processes. Sriram is passionate about interdisciplinary collaboration and is always eager to learn new techniques and explore innovative approaches in biomedical research.

Selected Publications

  1. Sriram, M., Priya, S., & Katti, D. S. (2024). Polyhydroxybutyrate-based osteoinductive mineralized electrospun structures that mimic components and tissue interfaces of the osteon for bone tissue engineering. Biofabrication, 16(2), 025036. https://doi.org/10.1088/1758-5090/ad331a
  2. Sriram, M., Priya, S., Mahajan, A., & Katti, D. S. (2024). Directing ligament-mimetic bi-directional cell organization in scaffolds through zone-specific microarchitecture for ligament tissue engineering. Biofabrication, 16(2), 025015. https://doi.org/10.1088/1758-5090/ad22f2
  3. Bhutada, S. S., Sriram, M., & Katti, D. S. (2021). Sulfated carboxymethylcellulose conjugated electrospun fibers as a growth factor presenting system for tissue engineering. Carbohydrate Polymers, 268, 118256. https://doi.org/10.1016/j.carbpol.2021.118256
  4. Arora, A., Sriram, M., Kothari, A., & Katti, D. S. (2017). Co-culture of infrapatellar fat pad–derived mesenchymal stromal cells and articular chondrocytes in plasma clot for cartilage tissue engineering. Cytotherapy, 19(7), 881-894. https://doi.org/10.1016/j.jcyt.2017.04.003
  5. Sainitya, R., Sriram, M., Kalyanaraman, V., Dhivya, S., Saravanan, S., Vairamani, M., Sastry, T. P., & Selvamurugan, N. (2015). Scaffolds containing chitosan/carboxymethyl cellulose/mesoporous wollastonite for bone tissue engineering. International Journal of Biological Macromolecules, 80, 481-488. https://doi.org/10.1016/j.ijbiomac.2015.07.016
  6. Sriram, M., Sainitya, R., Kalyanaraman, V., Dhivya, S., & Selvamurugan, N. (2015). Biomaterials mediated microRNA delivery for bone tissue engineering. International Journal of Biological Macromolecules, 74, 404-412. https://doi.org/10.1016/j.ijbiomac.2014.12.034

Recent Publications