Ryosuke NISHIMURA
Research Fellow, Mechanobiology Institute, National University of Singapore
nishi@nus.edu.sg
Level 9 T-Lab
National University of Singapore
5A Engineering Drive 1
Singapore 117411
Ryosuke Nishimura
Research Fellow
Principal Investigator
Research Interests
Molecular Mechanics of Mechanotransduction
Selected Publications
- Nishimura, R., Kato, K., Saida, M., Kamei, Y., Takeda M., Miyoshi H., Yamagata Y., Amano, Y., and Yonemura S. Appropriate tension sensitivity of α-catenin ensures rounding morphogenesis of epithelial spheroids. Cell Struct. Funct. 2022; 47, 55–73. [PMID: 35732428]
Recent Publications
- Nishimura R, and Kanchanawong P. Nanoscale mechano-adaption of integrin-based cell adhesions: New tools and techniques lead the way. Curr Opin Cell Biol 2025; 94:102509. [PMID: 40188780]
- Morales-Camilo N, Liu J, Ramírez MJ, Canales-Salgado P, Alegría JJ, Liu X, Ong HT, Barrera NP, Fierro A, Toyama Y, Goult BT, Wang Y, Meng Y, Nishimura R, Fong-Ngern K, Low CSL, Kanchanawong P, Yan J, Ravasio A, and Bertocchi C. Alternative molecular mechanisms for force transmission at adherens junctions via β-catenin-vinculin interaction. Nat Commun 2024; 15(1):5608. [PMID: 38969637]
About Ryosuke
During his Ph.D., he investigated how the tension sensitivity of α-catenin is involved in the multicellular morphogenesis of epithelia. In MBI, he is working on 1) the development of optogenetic tools to control force transmission at cell-extracellular matrix (ECM) adhesions and 2) single-molecule dynamics of transmembrane receptors in the context of aging of retinal pigmented epithelia (RPE).
Outside work, he has an extraordinary passion for drinking, brewing, and roasting coffee.
