LEE Yaelim

Research Fellow, Mechanobiology Institute, National University of Singapore

Lee Yaelim

Research Fellow

Principal Investigator

GV Shivashankar, Rong Li

Recent Publications

  1. Lee Y, Shen X, Dreesen O, Zhua J, and Li R. Dysregulation of Extracellular Fibronectin and 5-integrin in Dermal Aging. Mol Biol Cell 2025;:mbcE25020074. [PMID: 40560397]
  2. Wang H, Huang Z, Shen X, Lee Y, Song X, Shu C, Wu LH, Pakkiri LS, Lim PL, Zhang X, Drum CL, Zhu J, and Li R. Rejuvenation of aged oocyte through exposure to young follicular microenvironment. Nat Aging 2024;. [PMID: 39251866]
  3. Ong JLK, Jalaludin NFF, Wong MK, Tan SH, Angelina C, Sukhatme SA, Yeo T, Lim CT, Lee YT, Soh SY, Lim TKH, Tay TKY, Chang KTE, Chen ZX, and Loh AH. Exosomal mRNA Cargo are biomarkers of tumor and immune cell populations in pediatric osteosarcoma. Transl Oncol 2024; 46:102008. [PMID: 38852279]
  4. Makhija E, Zheng Y, Wang J, Leong HR, Othman RB, Ng EX, Lee EH, Kellogg LT, Lee YH, Yu H, Poon Z, and Van Vliet KJ. Topological defects in self-assembled patterns of mesenchymal stromal cells in vitro are predictive attributes of condensation and chondrogenesis. PLoS One 2024; 19(3):e0297769. [PMID: 38547243]
  5. Chin T, Lee XE, Ng PY, Lee Y, and Dreesen O. The role of cellular senescence in skin aging and age-related skin pathologies. Front Physiol 2023; 14:1297637. [PMID: 38074322]
  6. Jun M, Lee YL, Zhou T, Maric M, Burke B, Park S, Low BC, and Chiam K. Subcellular Force Imbalance in Actin Bundles Induces Nuclear Repositioning and Durotaxis. ACS Appl Mater Interfaces 2023;. [PMID: 37674326]
  7. Loh AHP, Angelina C, Wong MK, Tan SH, Sukhatme SA, Yeo T, Lim SB, Lee YT, Soh SY, Leung W, Chang KTE, Chua YW, Alkaff SMF, Lim TKH, Lim CT, and Chen ZX. Pro-metastatic and mesenchymal gene expression signatures characterize circulating tumor cells of neuroblastoma patients with bone marrow metastases and relapse. Front Oncol 2022; 12:939460. [PMID: 36176417]
  8. Wang H, Hu J, Yi K, Ma Z, Song X, Lee Y, Kalab P, Bershadsky AD, Miao Y, and Li R. Dual control of formin-nucleated actin assembly by the chromatin and ER in mouse oocytes. Curr Biol 2022;. [PMID: 35981539]
  9. Wu X, Chan C, Springs SL, Lee YH, Lu TK, and Yu H. A warm-start digital CRISPR/Cas-based method for the quantitative detection of nucleic acids. Anal Chim Acta 2022; 1196:339494. [PMID: 35151407]
  10. Zhu B, Finch-Edmondson M, Leong KW, Zhang X, V M, Lin QXX, Lee Y, Ng WT, Guo H, Wan Y, Sudol M, and DasGupta R. LncRNA SFTA1P mediates positive feedback regulation of the Hippo-YAP/TAZ signaling pathway in non-small cell lung cancer. Cell Death Discov 2021; 7(1):369. [PMID: 34845189]

About Yaelim Lee

2017-Current: Research fellow, MBI, National University of Singapore, Singapore
2009-2016: Ph.D., University of Texas Austin, U.S.A
2006-2008: M.S., Korea University, South Korea
2002-2005: B.S., Korea University, South Korea

Current Projects

  • Development of a comprehensive toolset for interrogating transcription control in response to mechanical cues
  • The mechanical role of cellular senescence on physical tissue structure and function during skin ageing

Hometown: Seoul, Korea
Outside of work: Enjoying time with family