FOO Yong Hwee
Alumni, Mechanobiology Institute, National University of Singapore
mbifyh@nus.edu.sg
Level 10 T-Lab
National University of Singapore
5A Engineering Drive 1
Singapore 117411
Foo Yong Hwee
Alumni
I did my B.Sc. in the department of chemistry at the National University of Singapore (NUS), majoring in analytic chemistry. I was then employed by Singapore Eye Research Institute and worked in the area of biomarker discovery related to eye diseases using nano-spray liquid chromatography-tandem mass spectrometry. I was also involved in the synthesis of antimicrobial peptides using solid phase peptide synthesis.
Two years later, I went on to pursue a Ph.D. in the field of fluorescence biophysics under Thorsten Wohland in NUS and Sohail Ahmed from the Institute of Medical Biology (A*Star) where I focused on using fluorescence cross-correlation spectroscopy (FCCS) to probe biomolecular interaction in living cells. I also had the opportunity to spend three months in the European Molecular Biology Laboratory (EMBL) in Heidelberg as a short-term follow.
After obtaining my Ph.D., I joined the Mechanobiology Institute in the lab of Linda J. Kenney as a research fellow working on understanding bacteria signaling by applying fluorescence methods.
Recent Publications
- Liew ATF, Foo YH, Gao Y, Zangoui P, Singh MK, Gulvady R, and Kenney LJ. Single cell, super-resolution imaging reveals an acid pH-dependent conformational switch in SsrB regulates SPI-2. Elife 2019; 8. [PMID: 31033442]
- Spahn C, Glaesmann M, Gao Y, Foo YH, Lampe M, Kenney LJ, and Heilemann M. Erratum to: Sequential Super-Resolution Imaging of Bacterial Regulatory Proteins, the Nucleoid and the Cell Membrane in Single, Fixed E. coli Cells. Methods Mol. Biol. 2017; 1624:E1. [PMID: 29151226]
- Gao Y, Foo YH, Winardhi RS, Tang Q, Yan J, and Kenney LJ. Charged residues in the H-NS linker drive DNA binding and gene silencing in single cells. Proc. Natl. Acad. Sci. U.S.A. 2017;. [PMID: 29109287]
- Spahn C, Glaesmann M, Gao Y, Foo YH, Lampe M, Kenney LJ, and Heilemann M. Sequential Super-Resolution Imaging of Bacterial Regulatory Proteins: The Nucleoid and the Cell Membrane in Single, Fixed E. coli Cells. Methods Mol. Biol. 2017; 1624:269-289. [PMID: 28842890]
- Macháň R, Foo YH, and Wohland T. On the Equivalence of FCS and FRAP: Simultaneous Lipid Membrane Measurements. Biophys. J. 2016; 111(1):152-61. [PMID: 27410743]
- Foo YH, Spahn C, Zhang H, Heilemann M, and Kenney LJ. Single cell super-resolution imaging of E. coli OmpR during environmental stress. Integr Biol (Camb) 2015; 7(10):1297-308. [PMID: 26156621]
- Foo YH, Gao Y, Zhang H, and Kenney LJ. Cytoplasmic sensing by the inner membrane histidine kinase EnvZ. Prog. Biophys. Mol. Biol. 2015; 118(3):119-29. [PMID: 25937465]
