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Women in Science talk

My journey from cytosol to cell wall

by Prof. Manjula Reddy, CCMB Hyderabad

A reception will be held afterward in the 10th floor lobby of MBI.

Research Interests: Our laboratory is interested in studying prokaryotic cell division (cytokinesis) and its regulation using a Gram-negative model bacterium, Escherichia coli K12 and Mycobacterium smegmatis, a surrogate model organism that is used to understand the biology of M. tuberculosis, a human pathogen that causes tuberculosis.

Selected Publications

  • Parveen, S., and M. Reddy (2017) Identification of YfiH (PgeF) as a factor contributing to the maintenance of bacterial peptidoglycan composition (in press, Mol Microbiol)
  • Singh SK, Parveen S, SaiSree L, Reddy M. (2015) Regulated proteolysis of a cross-link specific peptidoglycan hydrolase contributes to bacterial morphogenesis. Proc Natl Acad Sci U S A. 112: 10956-10961.
  • Mahalakshmi, S., M. R. Sunayana, L. SaiSree, and M. Reddy. (2014) yciM is an essential gene required for regulation of lipopolysaccharide synthesis in Escherichia coli. Mol Microbiol 91: 145-157.
  • Singh SK, L SaiSree, RN Amrutha and M Reddy. 2012. Three redundant murein endopeptidases catalyse an essential cleavage step in peptidoglycan synthesis of Escherichia coli. Mol Microbiol 86: 1036-1051

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About the National University of Singapore

About NUSA leading global university centred in Asia, NUS is Singapore's flagship university, offering a global approach to education and research with a focus on Asian perspectives and expertise.

About the Mechanobiology Institute, National University of Singapore

About MBIOne of four Research Centres of Excellence at NUS, MBI is working to identify, measure and describe how the forces for motility and morphogenesis are expressed at the molecular, cellular and tissue level.
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