Yusuke HARA
Alumni, Mechanobiology Institute, National University of Singapore
mbiyusu@nus.edu.sg
Level 10 T-Lab
National University of Singapore
5A Engineering Drive 1
Singapore 117411
How do lipid bilayer components move?
How do lipid bilayer components move? One of the tenets of the Fluid-Mosaic membrane model is that the components of the bilayers are free to move. Before describing the differences between lipid and protein [...]
How do mechanically-gated ion channels facilitate mechanotransduction?
How do mechanically-gated ion channels facilitate mechanotransduction? Mechanotransduction relies on the ability of cells to convert mechanical cues, such as stretch or compression, to biochemical signals. One way this occurs is through the activity [...]
What are cytoskeletal cages?
What are cytoskeletal cages? Cytoskeletal components can assemble into cage-like structures within the cell. These cages serve to segregate intracellular regions or organelles, and can protect their contents from mechanical stress. At the level [...]
What is Myosin Light Chain Kinase?
What is Myosin Light Chain Kinase? Myosin light chain kinase (MLCK) is a calcium/calmodulin-dependent serine/threonine kinase, belonging to the immunoglobulin superfamily. It phosphorylates the regulatory myosin light chains of myosin II, in order to [...]
Membrane Dynamics
What are cell membranes? What are the physiological functions of biological membranes? Eukaryotic cells and their organelles are enveloped by viscoelastic layers made of lipids and proteins. These layers are generally referred to as [...]
Cytoskeleton Dynamics
Cytoskeleton Dynamics The cytoskeleton is a highly dynamic network of filamentous proteins that exists in the 3D space to link all regions and components of the cell. All cells, including bacteria, have a cytoskeleton [...]
Yusuke Hara
Alumni
Recent Publications
- Sun Z, Amourda C, Shagirov M, Hara Y, Saunders TE, and Toyama Y. Author Correction: Basolateral protrusion and apical contraction cooperatively drive Drosophila germ-band extension. Nat. Cell Biol. 2018;. [PMID: 29507405]
- Hara Y. Contraction and elongation: Mechanics underlying cell boundary deformations in epithelial tissue. Dev. Growth Differ. 2017;. [PMID: 28573735]
- Ding WY, Ong HT, Hara Y, Wongsantichon J, Toyama Y, Robinson RC, Nédélec F, and Zaidel-Bar R. Plastin increases cortical connectivity to facilitate robust polarization and timely cytokinesis. J. Cell Biol. 2017;. [PMID: 28400443]
- Sun Z, Amourda C, Shagirov M, Hara Y, Saunders TE, and Toyama Y. Basolateral protrusion and apical contraction cooperatively drive Drosophila germ-band extension. Nat. Cell Biol. 2017;. [PMID: 28346438]
- Bertocchi C, Wang Y, Ravasio A, Hara Y, Wu Y, Sailov T, Baird MA, Davidson MW, Zaidel-Bar R, Toyama Y, Ladoux B, Mege R, and Kanchanawong P. Nanoscale architecture of cadherin-based cell adhesions. Nat. Cell Biol. 2016;. [PMID: 27992406]
- Hara Y, Shagirov M, and Toyama Y. Cell Boundary Elongation by Non-autonomous Contractility in Cell Oscillation. Curr. Biol. 2016; 26(17):2388-96. [PMID: 27524484]
