Toyama Group

Yusuke HARA

Alumni, Mechanobiology Institute, National University of Singapore

mbiyusu@nus.edu.sg
Level 10 T-Lab
National University of Singapore
5A Engineering Drive 1
Singapore 117411

Force sensing in cells at the single molecule level

Professor Yan Jie and his team from the Mechanobiology Institute collaborated with Professor Liu Xiaogang from the Department of Chemistry, NUS, to determine the exact force needed to activate Piezo1, via a DNA-based approach.

By Yee Shu Brenda|May 5th, 2026|Categories: News, Yan Jie Lab|Comments Off on Force sensing in cells at the single molecule level

MBI Hosts Students from Raffles Girls School!

MBI hosted students from Raffles Girls School on 28 April 2026, for an outreach session designed to spark curiosity about mechanobiology and research careers.

By Yee Shu Brenda|Apr 29th, 2026|Categories: MBInsights, News|Comments Off on MBI Hosts Students from Raffles Girls School!

Yusuke Hara

Alumni

Principal Investigator

Yusuke Toyama

Research Interests

Mechanotransduction in Tissues

Recent Publications

  1. Sun Z, Amourda C, Shagirov M, Hara Y, Saunders TE, and Toyama Y. Author Correction: Basolateral protrusion and apical contraction cooperatively drive Drosophila germ-band extension. Nat. Cell Biol. 2018;. [PMID: 29507405]
  2. Hara Y. Contraction and elongation: Mechanics underlying cell boundary deformations in epithelial tissue. Dev. Growth Differ. 2017;. [PMID: 28573735]
  3. Ding WY, Ong HT, Hara Y, Wongsantichon J, Toyama Y, Robinson RC, Nédélec F, and Zaidel-Bar R. Plastin increases cortical connectivity to facilitate robust polarization and timely cytokinesis. J. Cell Biol. 2017;. [PMID: 28400443]
  4. Sun Z, Amourda C, Shagirov M, Hara Y, Saunders TE, and Toyama Y. Basolateral protrusion and apical contraction cooperatively drive Drosophila germ-band extension. Nat. Cell Biol. 2017;. [PMID: 28346438]
  5. Bertocchi C, Wang Y, Ravasio A, Hara Y, Wu Y, Sailov T, Baird MA, Davidson MW, Zaidel-Bar R, Toyama Y, Ladoux B, Mege R, and Kanchanawong P. Nanoscale architecture of cadherin-based cell adhesions. Nat. Cell Biol. 2016;. [PMID: 27992406]
  6. Hara Y, Shagirov M, and Toyama Y. Cell Boundary Elongation by Non-autonomous Contractility in Cell Oscillation. Curr. Biol. 2016; 26(17):2388-96. [PMID: 27524484]
By Management|2018-02-20T13:14:57+08:00Apr 20th, 2017|Categories: Alumni, Toyama Alumni|Comments Off on Yusuke Hara

About the National University of Singapore

About NUSA leading global university centred in Asia, NUS is Singapore's flagship university, offering a global approach to education and research with a focus on Asian perspectives and expertise.

About the Mechanobiology Institute, National University of Singapore

About MBIOne of four Research Centres of Excellence at NUS, MBI is working to identify, measure and describe how the forces for motility and morphogenesis are expressed at the molecular, cellular and tissue level.
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