NAI Mui Hoon Brenda

Alumni, Research Associate, Mechanobiology Institute, National University of Singapore

mbinmhb@nus.edu.sg
Level 10 T-Lab
National University of Singapore
5A Engineering Drive 1
Singapore 117411

Nai Mui Hoon Brenda

Alumni, Research Associate

Principal Investigator

Lim Chwee Teck

Research Interests

Technology Innovation for Mechanobiology

Recent Publications

  1. Zhang X, Bai J, Fan S, Liang L, Song X, Nai MH, Zhang R, Chen M, Wang J, and Lim CT. Dissecting Exosomal-Tumoral-Vascular Interactions of Single Tumor Cells and Clusters Using a Tumoral-Transendothelial Migration Chip. ACS Nano 2025;. [PMID: 40556461]
  2. Mitra A, Cutiongco MFA, Burla R, Zeng Y, Na Q, Kong M, Vinod B, Nai MH, Hübner B, Ludwig A, Lim CT, Shivashankar GV, Saggio I, and Zhao W. Acute chromatin decompaction stiffens the nucleus as revealed by nanopillar-induced nuclear deformation in cells. Proc Natl Acad Sci U S A 2025; 122(19):e2416659122. [PMID: 40343993]
  3. Kwokdinata C, Ramanujam V, Chen J, de Oliveira PN, Nai MH, Chooi WH, Lim CT, Ng SY, David L, and Chew SY. Encapsulation of Human Spinal Cord Progenitor Cells in Hyaluronan-Gelatin Hydrogel for Spinal Cord Injury Treatment. ACS Appl Mater Interfaces 2023;. [PMID: 37751213]
  4. Kenry , Yeo T, She DT, Nai MH, Marcelo Valerio VL, Pan Y, Middha E, Lim CT, and Liu B. Differential Collective Cell Migratory Behaviors Modulated by Phospholipid Nanocarriers. ACS Nano 2021;. [PMID: 34767716]
  5. Chakraborty S, Sampath D, Yu Lin MO, Bilton M, Huang C, Nai MH, Njah K, Goy P, Wang C, Guccione E, Lim C, and Hong W. Agrin-Matrix Metalloproteinase-12 axis confers a mechanically competent microenvironment in skin wound healing. Nat Commun 2021; 12(1):6349. [PMID: 34732729]
  6. Wang M, Nai MH, Huang RY, Leo HL, Lim CT, and Chen C. High-throughput functional profiling of single adherent cells via hydrogel drop-screen. Lab Chip 2021;. [PMID: 33506832]
  7. Hu B, Berkey C, Feliciano T, Chen X, Li Z, Chen C, Amini S, Nai MH, Lei Q, Ni R, Wang J, Leow WR, Pan S, Li Y, Cai P, Miserez A, Li S, Lim CT, Wu Y, Odom TW, Dauskardt RH, and Chen X. Thermal-Disrupting Interface Mitigates Intercellular Cohesion Loss for Accurate Topical Antibacterial Therapy. Adv. Mater. Weinheim 2020;:e1907030. [PMID: 32072703]
  8. Narayanaswamy A, Nai MH, Nongpiur ME, Htoon HM, Thomas A, Sangtam T, Lim CT, Wong TT, and Aung T. Young's Modulus Determination of Normal and Glaucomatous Human Iris. Invest. Ophthalmol. Vis. Sci. 2019; 60(7):2690-2695. [PMID: 31242291]
  9. Zhao Y, Zhang G, Nai MH, Ding G, Li D, Liu Y, Hippalgaonkar K, Lim CT, Chi D, Li B, Wu J, and Thong JTL. Probing the Physical Origin of Anisotropic Thermal Transport in Black Phosphorus Nanoribbons. Adv. Mater. Weinheim 2018;:e1804928. [PMID: 30307655]
  10. Kenry , Lim YB, Nai MH, Cao J, Loh KP, and Lim CT. Graphene oxide inhibits malaria parasite invasion and delays parasitic growth in vitro. Nanoscale 2017;. [PMID: 28901366]

Selected Publications

  1. Ultralow thermal conductivity of single-crystalline porous silicon nanowires
    Zhao,Y, L Yang, L Kong, M H Nai, D Liu, J Wu, Y Liu, S Y Chiam, W K Chim, C T Lim, B Li, J T L Thong, K Hippalgaonkar, Advanced Functional Materials, 2017.
    http://iopscience.iop.org/article/10.1088/2053-1591/aa584d/meta
  2. Graphene oxide inhibits malaria parasite invasion and delays parasitic growth in vitro
    Kenry, Y B Lim, M H Nai, J S Cao, K P Loh, C T Lim, Nanoscale, 2017.Abstract
    http://pubs.rsc.org/en/Content/ArticleLanding/2017/NR/C7NR06007F#!divAbstract
  3. Orientational coupling locally orchestrates cell migration pattern for re-epithelialization
    Hu, B, W R Leow, S Amini, B Nai, X Zhang, Z Liu, P Cai, Z Li, Y-L Wu, A Miserez, C T Lim, X Chen, Advanced Materials, 29, 29, 1700145, 2017.
    https://www.ncbi.nlm.nih.gov/pubmed/28585393
  4. Ageing properties of polyurethane methacrylate and off-stoichiometry thiol-ene polymers after nitrogen and argon plasma treatment
    Chen, T F, K S Siow*, P Y Ng, M H Nai, C T Lim, B Y Majlis, Journal of Applied Polymer Science, 133, 42, 44107, 2016.
    http://onlinelibrary.wiley.com/doi/10.1002/app.44107/abstract
  5. Large-area, periodic, hexagonal wrinkles on nanocrystalline graphitic film
    Liu, Y, Kenry, Y Guo, S Sonam, S K Hong, M H Nai, C T Nai, L Gao, J Chen, B J Cho, C T Lim, W Guo, K P Loh, Advanced Functional Materials, 25, 34, 5492–5503, 2015.
    http://onlinelibrary.wiley.com/doi/10.1002/adfm.201502010/abstract
  6. Viscoelastic effects of silicone gels at the micro- and nanoscale
    Kenry, M C Leong, M H Nai, F C Cheong, C T Lim, Procedia IUTAM, 12, 20-30, 2015.
    http://www.sciencedirect.com/science/article/pii/S2210983814000777
  7. Polysaccharide nanofibers with variable compliance for directing cell fate
    Xu, J, M H Nai, C T Lim, C Le Visage, J K Y Chan, S Y Chew, Journal of Biomedical Materials Research. Part A, 103, 3, 959-968, 2015.
    https://www.ncbi.nlm.nih.gov/pubmed/?term=24853353
  8. Young’s modulus determination of normal and glaucomatous human irides
    Narayanaswamy, A K, M H Nai, C T Lim, T Aung, Investigative Ophthalmology & Visual Science (Abstract), 56, 7, 2015.
    http://iovs.arvojournals.org/article.aspx?articleid=2336247