Bibhas ROY
Visiting Research Fellow, Mechanobiology Institute, National University of Singapore, Post-doctoral Fellow, FIRC Institute of Molecular Oncology (IFOM), Italy
mbibr@nus.edu.sg
Level 10 T-Lab
National University of Singapore
5A Engineering Drive 1
Singapore 117411
Congratulations to Kim Whye Leong for presenting excellent work at the Imaging Mouse Development Workshop held at EMBL Heidelberg!
Congratulations to Kim Whye Leong for presenting excellent work at the Imaging Mouse Development Workshop held at EMBL Heidelberg from 2 to 5 Sept 2024. Thanks for all the feedback from the expert audience!
Seeking Research Assistant in the labs of Dr. Natalie Dye and Dr. Alphée Michelot at the Mechanobiology Institute, NUS
We are seeking a Research Assistant to join the labs of Dr. Natalie Dye and Dr. Alphée Michelot at the Mechanobiology Institute, NUS.
Seeking Postdoctoral Research Fellow in the Chan Laboratory, Mechanobiology Institute, NUS
We are seeking to recruit a Postdoctoral Research Fellow in the Chan Laboratory at the Mechanobiology Institute, NUS.
Welcome to Daniel!
Daniel is a UROP intern who will be applying a machine learning approach to study follicle development.
Le Mai Tan Dat (Daniel)
UROPS Intern, Chan Group
Wang Shida
PhD Student, Class of August 2024, Lim Group
Bibhas Roy
Alumni
I am a Research Fellow in Nuclear Mechanics & Genome Regulation Laboratory at MBI. In my doctoral research at Indian Institute of Technology Kharagpur, I have been understanding about the cellular mechanotransduction which specifically deals with cell membrane mechanosensors and consequent downstream cell responses. Eventually I have quite interested on nuclear mechanotransduction because for last two decades several path breaking findings in cellular mechanobiology has gained enormous interest to scientific community, but the nuclear mechanotransduction field remains quite elusive. This drive brought me to Prof Shivashankar’s Lab at MBI.
During differentiation and also reprogramming, cells accumulated multiple epigenetic changes, which leads to differential type of gene expression in different cell types. My current endeavor explores how nuclear geometry driven epigenetic changes leads to different cell type commitment.
Recent Publications
- Yuan L, Roy B, Ratna P, Uhler C, and Shivashankar GV. Lateral confined growth of cells activates Lef1 dependent pathways to regulate cell-state transitions. Sci Rep 2022; 12(1):17318. [PMID: 36243826]
- Roy B, Yuan L, Lee Y, Bharti A, Mitra A, and Shivashankar GV. Fibroblast rejuvenation by mechanical reprogramming and redifferentiation. Proc. Natl. Acad. Sci. U.S.A. 2020;. [PMID: 32350144]
- Banerjee H, Roy B, Chaudhury K, Srinivasan B, Chakraborty S, and Ren H. Frequency-induced morphology alterations in microconfined biological cells. Med Biol Eng Comput 2018;. [PMID: 30415434]
- Roy B, Venkatachalapathy S, Ratna P, Wang Y, Jokhun DS, Nagarajan M, and Shivashankar GV. Laterally confined growth of cells induces nuclear reprogramming in the absence of exogenous biochemical factors. Proc. Natl. Acad. Sci. U.S.A. 2018;. [PMID: 29735717]
