CHII JOU (JOE) CHAN LABORATORY

Mammalian Development and Tissue Hydraulics Laboratory

Our research aims to address two broad questions in developmental biology: How are tissue size and shape precisely controlled during early mammalian development? How is tissue geometry sensed and transmitted to the cellular level to impact cellular functions? How are mechanics and biochemical signalling integrated across multiple scales to ensure robust morphogenesis and patterning?

To address these fundamental questions, we focus on understanding mammalian follicle development, which is critical for the maturation of functional eggs for successful reproduction. We aim to identify the me