Singapore Fish Meeting  |  2nd October 2018
Mechanobiology Institute, National University of Singapore

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MECHANOBIOLOGY INSTITUTE, NATIONAL UNIVERSITY OF SINGAPORE

Singapore Fish Meeting 2018

The Singapore Fish Meeting 2018 will gather laboratories in Singapore that use fish models (zebrafish, medaka, killifish, etc.) to address key scientific questions. Scientists will present their latest findings in development, disease, and regeneration. Additionally, some presenters will show how ingenious use of fish models can help to answer important questions concerning behavioural science, fluid mechanics, human bacterial pathogenesis, and tumorigenesis.

The organizers hope the meeting will foster a closer network of fish scientists, create a platform to promote the use of fish models for scientific discoveries and serve as a catalyst for cross-disciplinary collaborations.

ORGANISED BY

Mechanobiology Institute, National University of Singapore (MBI)

MBI has been at the global frontier in understanding the minute world of cells interacting with their physical environment. Increasingly, scientists are beginning to uncover new knowledge in vertebrate development, regeneration and disease etiology through the lens of mechanobiology. MBI is pleased to host 2018’s meeting in hopes of promoting new collaborations and partnerships that will lead to new breakthroughs.

Speakers

Speakers

Oral Presentation 1

Tay Huiping Shermaine

Christoph Winkler Lab/Department of Biological Sciences, NUS

PRESENTING
Splicing analysis in a zebrafish model for Spinal Muscular Atrophy identifies transcripts important for motor neuron and Schwann cell function

Catherine Hor

Eyleen Goh Lab/Duke­NUS Medical School/ NNI

PRESENTING
Disease modeling of Carpenter Syndrome in Rab23 zebrafish and mouse mutants reveals ciliopathy

Yiliu Zhang

Sudipto Roy Lab/Institute of Molecular and Cellular Biology

PRESENTING
Developing distinct types of cilia for the nose

Yap Choon Hwai

Yap Choon Hwai Lab/Department of Biomedical Engineering, NUS

PRESENTING
Image­Based Computational Tools for Understanding Fluid Dynamics in the Zebrafish Embryonic Heart

Zhang Changqing

Tom Carney Lab/LKC School of Medicine

PRESENTING
The Regulation of Zebrafish Epidermal Subdomains

Stuti Desai

Linda Kenney Lab/Mechanobiology Institute

PRESENTING
Making of Typhoid Mary: Persistence of Salmonella Typhi in Zebrafish

Oral Presentation 2

Kyle Buchan

Linda Kenney Lab/Mechanobiology Institute

PRESENTING
Building Humanised Models of Staphylococcus aureus Infection

Ma Jiajia

Tom Carney Lab/LKC School of Medicine

PRESENTING
A proteolytic regulator of epidermal integrity and inflammation

Tan Wen Hui

Christoph Winkler Lab/Department of Biological Sciences, NUS

PRESENTING
Transcriptome profiling of bone cells in a medaka osteoporosis model identifies novel mediators of bone repair

Stella Amanda

Takaomi Sanda Lab/NUS/Cancer Science Institute

PRESENTING
Development of the First Transgenic Animal Model for IRF4­induced T­cell Malignancy

Caroline Wee

Sudipto Roy Lab/Institute of Molecular and Cellular Biology

PRESENTING
Neural Circuits for Appetite Control in Zebrafish: Current Knowledge and Future Directions

Caroline Kibat

Ajay Mathuru Lab/Yale­NUS

PRESENTING
Role of α3 subunit containing nicotinic acetylcholine receptors in addiction

Posters

Ruey­Kuang Cheng

Suresh Jesuthasan Lab/LKC School of Medicine

PRESENTING
Inhibition of zebrafish lateral habenula revealed by in vivo electrophysiological recordings

Vindhya

Christoph Winkler Lab/Department of Biological Sciences, NUS

PRESENTING
Characterization of novel candidate genes identified in a zebrafish model for Spinal Muscular Atrophy

Serene Gwee

Christoph Winkler Lab/Department of Biological Sciences, NUS

PRESENTING
Aurora kinase B (AurkB) is involved in the modulating the neuronal development of zebrafish spinal motor neurons

Lucy Sharples

Sudipto Roy Lab/IMCB

PRESENTING
Disrupted­in­schizophrenia 1 regulates development of the hypothalamus and its related behaviours in zebrafish larvae

Stylianos Makrogkikas

Sudipto Roy Lab/IMCB

PRESENTING
The elucidation of the molecular and cellular mechanism of function of the pkhd1l1 genes in zebrafish

Xueyan Shen

Koh Tong Wey Lab/TLL

PRESENTING
Optimizations for single­cell transcriptomics to study cellular aging in the hypothalamus of Nothobranchius furzeri

Jason Lai

Timothy Saunders Lab/MBI

PRESENTING
Exploring the roles of the Hippo signalling pathway in somite morphogenesis

Abraha Gebregziabher Kahsay

Tom Carney Lab/LKC School of Medicine

PRESENTING
Developing a Zebrafish Model of Epidermolysis Bullosa Simplex

Claire Alexandra Scott

Tom Carney Lab/IMCB

PRESENTING
Developmental and regenerative biology (TBC)

Programme

Programme Overview

12:30PM Registration
Setup posters and oral presentations
Level 5 conference room
1:00PM

Oral Presentation 1
(Chaired by Timothy Saunders)

Level 5 conference room

Welcome note by Jason Lai

Tay Huiping Shermaine (Christoph Winkler Lab)
Splicing analysis in a zebrafish model for Spinal Muscular Atrophy identifies transcripts important for motor neuron and Schwann cell function

Catherine Hor (Eyleen Goh Lab)
Disease modeling of Carpenter Syndrome in Rab23 zebrafish and mouse mutants reveals ciliopathy

Yiliu Zhang (Sudipto Roy Lab)
Developing distinct types of cilia for the nose

Yap Choon Hwai (Yap Choon Hwai Lab)
Image-Based Computational Tools for Understanding Fluid Dynamics in the Zebrafish Embryonic Heart

ZHANG CHANGQING (Tom Carney Lab)
The Regulation of Zebrafish Epidermal Subdomains

Stuti Desai (Linda Kenney Lab)
Making of Typhoid Mary: Persistence of Salmonella Typhi in Zebrafish

3:10PM Coffee break & poster session
Level 10 lounge
4:20PM

Oral Presentation 2
(Chaired by Christoph Winkler)

Level 5 conference room

Kyle Buchan (Linda Kenney Lab)
Building Humanised Models of Staphylococcus aureus Infection

Ma Jiajia (Tom Carney Lab)
A proteolytic regulator of epidermal integrity and inflammation

Tan Wen Hui (Christoph Winkler Lab)
Transcriptome profiling of bone cells in a medaka osteoporosis model identifies novel mediators of bone repair

Stella Amanda (Takaomi Sanda Lab)
Development of the First Transgenic Animal Model for IRF4-induced T-cell Malignancy

Caroline Wee (Sudipto Roy Lab)
Neural Circuits for Appetite Control in Zebrafish: Current Knowledge and Future Directions

Caroline Kibat (Ajay Mathuru Lab)
Role of α3 subunit containing nicotinic acetylcholine receptors in addiction

Closing & Conclusion by Jason Lai

6:30PM Dinner and drinks
Level 10 lounge
8:00PM End

Registration and Fees

Registration

Registration for talks and posters is now closed. However, if you’d like to attend the meeting please drop an email to Jason Lai at jason.lai@nus.edu.sg before Wednesday 26th September so we know numbers for refreshments.

Venue

Mechanobiology Institute, National University of Singapore

National University of Singapore
T-Lab
Seminar Room, Level 5
5A Engineering Drive 1
Singapore 117411

+65 6872 6123
mbi.nus.edu.sg

Map

Organizing Committee

Timothy Saunders

Mechanobiology Institute, NUS

Jason Lai

Mechanobiology Institute, NUS

Supporting Organizations and Sponsors

The organizers would like to thank the following organizations and sponsors for their support of our meeting

Supporting Organizations

The Mechanobiology Institute, Singapore (MBI)

The MBI, headed by Prof Michael Sheetz,  was established in 2009, through joint funding by the National Research Foundation and the Ministry of Education of Singapore, with the goal of creating a new cutting edge research center focusing on diverse aspects of mechanobiology. The primary goal of the MBI is to identify, measure and describe the roles of forces in driving cell motility and morphogenesis, and characterize the mechanisms underlying these processes at the molecular, cellular and tissue levels. Toward that goal, the MBI working to create a common international standard for defining these steps by developing powerful new computational models, experimental reagents, and tools for studying cells and tissues, either healthy or diseased. These ambitious objectives are addressed by interdisciplinary teams drawn from Singapore and international researchers in medicine, biology, chemistry, physics, engineering and computing.

Learn more about MBI

Corporate Sponsors