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PRODID:-//Mechanobiology Institute, National University of Singapore - ECPv6.15.12.2//NONSGML v1.0//EN
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METHOD:PUBLISH
X-WR-CALNAME:Mechanobiology Institute, National University of Singapore
X-ORIGINAL-URL:https://www.mbi.nus.edu.sg
X-WR-CALDESC:Events for Mechanobiology Institute, National University of Singapore
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BEGIN:VTIMEZONE
TZID:Asia/Singapore
BEGIN:STANDARD
TZOFFSETFROM:+0800
TZOFFSETTO:+0800
TZNAME:+08
DTSTART:20190101T000000
END:STANDARD
END:VTIMEZONE
BEGIN:VEVENT
DTSTART;TZID=Asia/Singapore:20200204T100000
DTEND;TZID=Asia/Singapore:20200204T110000
DTSTAMP:20260417T082145
CREATED:20200130T014947Z
LAST-MODIFIED:20200130T015130Z
UID:28548-1580810400-1580814000@www.mbi.nus.edu.sg
SUMMARY:MBI SPSS: Harnessing the proliferative activity of YAP through optogenetics by Toh Jia Ying Pearlyn
DESCRIPTION:MBI Student and Postdoc Seminar Series (SPSS)\nTime: 10.00am – 11.00am\nDate: Tuesday\, 4 February 2020\nVenue: Level 5 Meeting Room 1\, T-Lab \nHarnessing the proliferative activity of YAP through optogenetics.\nBy Toh Jia Ying Pearlyn\, PhD Student\, Sheetz Group \n  \nPlease note this event is open to MBI researchers and invited guests only.
URL:https://www.mbi.nus.edu.sg/event/mbi-spss-harnessing-the-proliferative-activity-of-yap-through-optogenetics-by-toh-jia-ying-pearlyn/
LOCATION:MBI Seminar Room Lvl 5\, T-Lab\, Level 5\, 5A Engineering Drive 1\, Mechanobiology Institute\, National University of Singapore\, 117411\, Singapore
CATEGORIES:MBI Student & Postdoc Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Singapore:20200207T100000
DTEND;TZID=Asia/Singapore:20200207T110000
DTSTAMP:20260417T082145
CREATED:20200204T081451Z
LAST-MODIFIED:20200204T081451Z
UID:28732-1581069600-1581073200@www.mbi.nus.edu.sg
SUMMARY:MBIw: Hyaluronan receptor LYVE-1 expressing macrophages as master regulators of matrix in healthy tissue: relevance to ageing by Veronique Angeli
DESCRIPTION:MBI Weekly Meeting Seminar\nTime: 10.00am – 11.00am\nDate: Friday\, 7 February 2020\nVenue: Level 5 Meeting Room 1\, T-Lab \nHyaluronan receptor LYVE-1 expressing macrophages as master regulators of matrix in healthy tissue: relevance to ageing\nBy Prof. Veronique Angeli\, Associate Professor\, Department of Microbiology and Immunology\, NUS\, Singapore (host: Prof. Virgile Viasnoff) \nTissue resident macrophages can exert beyond their established immune functions additional activities to support tissue homeostasis and function. Recently\, we unveiled a hitherto unknown homeostatic functions for a population of tissue resident macrophages expressing hyaluronan receptor-LYVE-1. Utilizing a mouse model lacking specifically LYVE-1+ macrophages\, we showed in arteries that these macrophages prevent the vessels to become stiff by controlling the deposition of collagen in the arteries. Further mechanistic studies revealed that LYVE-1+ macrophage control collagen expression by vascular smooth muscle cells through its degradation. The relevance of these observations to vascular ageing which is characterized by arterial stiffening will be discussed. Furthermore\, we will share novel findings revealing that the homeostatic matrix remodeling function of LYVE-1+ macrophages is not limited to the arteries but also extended to the skin. In the latter\, LYVE-1+ macrophages are particularly abundant in the fascia and their absence leads to changes in elastin\, collagen and hyaluronan expression and collagen fiber organization that resemble those observed in aged skin. Therefore\, a better understanding of the communication between the matrix and LYVE-1+ macrophage is needed to better make use of these cells.
URL:https://www.mbi.nus.edu.sg/event/mbiw-hyaluronan-receptor-lyve-1-expressing-macrophages-as-master-regulators-of-matrix-in-healthy-tissue-relevance-to-ageing-by-veronique-angeli/
LOCATION:MBI Seminar Room Lvl 5\, T-Lab\, Level 5\, 5A Engineering Drive 1\, Mechanobiology Institute\, National University of Singapore\, 117411\, Singapore
CATEGORIES:MBI Weekly Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Singapore:20200211T100000
DTEND;TZID=Asia/Singapore:20200211T110000
DTSTAMP:20260417T082145
CREATED:20200205T022652Z
LAST-MODIFIED:20200205T022652Z
UID:28748-1581415200-1581418800@www.mbi.nus.edu.sg
SUMMARY:MBI SPSS: Physics of Early Stage Lumen Formation by Swati Sen
DESCRIPTION:MBI Student and Postdoc Seminar Series (SPSS)\nTime: 10.00am – 11.00am\nDate: Tuesday\, 11 February 2020\nVenue: Level 5 Meeting Room 1\, T-Lab \nPhysics of Early Stage Lumen Formation\nBy Swati Sen\, Research Fellow\, Prost Group \n  \nPlease note this event is open to MBI researchers and invited guests only.
URL:https://www.mbi.nus.edu.sg/event/mbi-spss-physics-of-early-stage-lumen-formation-by-swati-sen/
LOCATION:MBI Seminar Room Lvl 5\, T-Lab\, Level 5\, 5A Engineering Drive 1\, Mechanobiology Institute\, National University of Singapore\, 117411\, Singapore
CATEGORIES:MBI Student & Postdoc Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Singapore:20200211T103000
DTEND;TZID=Asia/Singapore:20200211T110000
DTSTAMP:20260417T082145
CREATED:20200205T022804Z
LAST-MODIFIED:20200205T022804Z
UID:28751-1581417000-1581418800@www.mbi.nus.edu.sg
SUMMARY:MBI SPSS: Microscopy: General applications and bits and pieces by Liu Jun
DESCRIPTION:MBI Student and Postdoc Seminar Series (SPSS)\nTime: 10.00am – 11.00am\nDate: Tuesday\, 11 February 2020\nVenue: Level 5 Meeting Room 1\, T-Lab \nMicroscopy: General applications and bits and pieces\nBy Liu Jun\, Superresolution\, FCS\, Microscopy \n  \nPlease note this event is open to MBI researchers and invited guests only.
URL:https://www.mbi.nus.edu.sg/event/mbi-spss-microscopy-general-applications-and-bits-and-pieces-by-liu-jun/
LOCATION:MBI Seminar Room Lvl 5\, T-Lab\, Level 5\, 5A Engineering Drive 1\, Mechanobiology Institute\, National University of Singapore\, 117411\, Singapore
CATEGORIES:MBI Student & Postdoc Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Singapore:20200218T100000
DTEND;TZID=Asia/Singapore:20200218T103000
DTSTAMP:20260417T082145
CREATED:20200214T070626Z
LAST-MODIFIED:20200413T064350Z
UID:28912-1582020000-1582021800@www.mbi.nus.edu.sg
SUMMARY:MBI SPSS: Mechanics of actomyosin contractile stress fibers by Yukako Nishimura
DESCRIPTION:MBI Student and Postdoc Seminar Series (SPSS)\nTime: 10.00am – 11.00am\nDate: Tuesday\, 18 February 2020\nVenue: Level 5 Meeting Room 1\, T-Lab \nMechanics of actomyosin contractile stress fibers\nBy Yukako Nishimura\, Research Fellow\, Viasnoff Group \n  \nPlease note this event is open to MBI researchers and invited guests only.
URL:https://www.mbi.nus.edu.sg/event/mbi-spss-mechanics-of-actomyosin-contractile-stress-fibers-by-yukako-nishimura/
LOCATION:MBI Seminar Room Lvl 5\, T-Lab\, Level 5\, 5A Engineering Drive 1\, Mechanobiology Institute\, National University of Singapore\, 117411\, Singapore
CATEGORIES:MBI Student & Postdoc Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Singapore:20200218T103000
DTEND;TZID=Asia/Singapore:20200218T110000
DTSTAMP:20260417T082145
CREATED:20200214T070748Z
LAST-MODIFIED:20200413T064304Z
UID:28915-1582021800-1582023600@www.mbi.nus.edu.sg
SUMMARY:MBI SPSS: Mechanical impact of apoptosis in compensatory cell division by Takumi Kawaue
DESCRIPTION:MBI Student and Postdoc Seminar Series (SPSS)\nTime: 10.00am – 11.00am\nDate: Tuesday\, 18 February 2020\nVenue: Level 5 Meeting Room 1\, T-Lab \n  \nMechanical impact of apoptosis in compensatory cell division\nBy Takumi Kawaue\, Visiting Research Fellow\, Toyama Group \n  \nPlease note this event is open to MBI researchers and invited guests only.
URL:https://www.mbi.nus.edu.sg/event/mbi-spss-mechanical-impact-of-apoptosis-in-compensatory-cell-division-by-takumi-kawaue/
LOCATION:MBI Seminar Room Lvl 5\, T-Lab\, Level 5\, 5A Engineering Drive 1\, Mechanobiology Institute\, National University of Singapore\, 117411\, Singapore
CATEGORIES:MBI Student & Postdoc Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Singapore:20200227T110000
DTEND;TZID=Asia/Singapore:20200227T120000
DTSTAMP:20260417T082145
CREATED:20200218T091348Z
LAST-MODIFIED:20200413T064159Z
UID:29046-1582801200-1582804800@www.mbi.nus.edu.sg
SUMMARY:MBI PhD Oral Defense: Resolving the Dynamics of Myofiber Morphogenesis
DESCRIPTION:MBI PhD Qualifying Exam\nTime: 11am\nDate: 27 February 2020\, Thursday\nVenue: T-Lab Level 5 Meeting Room 1 \nSupervisor: Prof Timothy Saunders \nCo-supervisor: Prof Sudipto Roy \nRESOLVING THE DYNAMICS OF MYOFIBER MORPHOGENESIS\nBy: Sunandan DHAR\,  Saunders Group \n  \n**Please note the examination following the seminar is closed-door**
URL:https://www.mbi.nus.edu.sg/event/phd-oral-defense-resolving-the-dynamics-of-myofiber-morphogenesis/
LOCATION:MBI Seminar Room Lvl 5\, T-Lab\, Level 5\, 5A Engineering Drive 1\, Mechanobiology Institute\, National University of Singapore\, 117411\, Singapore
CATEGORIES:PhD Oral Defense
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Singapore:20200227T160000
DTEND;TZID=Asia/Singapore:20200227T170000
DTSTAMP:20260417T082145
CREATED:20200204T082014Z
LAST-MODIFIED:20200204T082014Z
UID:28734-1582819200-1582822800@www.mbi.nus.edu.sg
SUMMARY:MBI PhD Oral Defence: Roles of BNIP-2 in mechanotransduction of cardiomyocyte differentiation  by Wong Chen Pei Darren
DESCRIPTION:MBI PhD Oral Defence\nTime: 4PM\nDate: Thursday\, 27 February 2020\nVenue: S3-05-02 – DBS CONFERENCE ROOM I (S3 LEVEL 5) \nSupervisor: Prof. Low Boon Chuan \nCo-Supervisor: Prof. Pakorn Tony Kanchanawong \nROLES OF BNIP-2 IN MECHANOTRANSDUCTION OF CARDIOMYOCYTE DIFFERENTIATION\nby WONG Chen Pei Darren\, Low Boon Chuan Group \nCardiac and skeletal muscles originate from the mesoderm and share many similarities during development. However\, there are biochemical and biophysical differences in terminally differentiated cardiac and skeletal muscles. The BCL2/adenovirus E1B 19 kDa-interacting protein 2 (BNIP-2) was previously found to promote skeletal muscle differentiation via activation of p38 MAPK through small GTPase Cdc42. Here\, we showed that BNIP-2 does not engage p38/Cdc42 node for cardiomyocyte differentiation. Instead\, BNIP-2 promotes cardiomyocyte differentiation though regulating LATS1 and cellular contractility. The significance of the novel role of BNIP-2 signalling in cardiomyocyte differentiation will be discussed. \n  \n**Please note the examination following the seminar is closed-door**
URL:https://www.mbi.nus.edu.sg/event/mbi-phd-oral-defence-roles-of-bnip-2-in-mechanotransduction-of-cardiomyocyte-differentiation-by-wong-chen-pei-darren/
LOCATION:MBI Seminar Room Lvl 5\, T-Lab\, Level 5\, 5A Engineering Drive 1\, Mechanobiology Institute\, National University of Singapore\, 117411\, Singapore
CATEGORIES:PhD Oral Defense
END:VEVENT
END:VCALENDAR