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X-WR-CALNAME:Mechanobiology Institute, National University of Singapore
X-ORIGINAL-URL:https://www.mbi.nus.edu.sg
X-WR-CALDESC:Events for Mechanobiology Institute, National University of Singapore
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BEGIN:VTIMEZONE
TZID:Asia/Shanghai
BEGIN:STANDARD
TZOFFSETFROM:+0800
TZOFFSETTO:+0800
TZNAME:CST
DTSTART:20160101T000000
END:STANDARD
END:VTIMEZONE
BEGIN:VEVENT
DTSTART;TZID=Asia/Shanghai:20171205T140000
DTEND;TZID=Asia/Shanghai:20171205T150000
DTSTAMP:20260408T111601
CREATED:20171129T010433Z
LAST-MODIFIED:20171129T010513Z
UID:21255-1512482400-1512486000@www.mbi.nus.edu.sg
SUMMARY:Topological Analysis of Cytoskeletal Networks from Single-Molecule Localization Microscopy Images by Zhang Zhen
DESCRIPTION:MBI PhD Oral Defense\nTime: 2pm-3pm\nDate: Tuesday\, 5 December 2017\nVenue: MBI\, level 5 meeting rooms\nSupervisor: Prof Kanchanawong\, Pakorn \nTopological Analysis of Cytoskeletal Networks from Single-Molecule Localization Microscopy  Images\nby Zhang Zhen\, Kanchanawong Group \nThe cytoskeletons are fundamental structural elements of the cells\, playing essential roles in the maintenance and regulation of cell shape\, cell mechanics\, and numerous cell behavioral programmes. Complex networks of the cytoskeletons permeate the cell interior and their architecture is a critical physical attribute governing their biological functions. However\, several challenges remain in the quantitative understanding of the cytoskeletons. In this dissertation\, I addressed these by an integrated approach combining super-resolution microscopy with advanced computational analysis. First\, a systematic optimization of single-molecule localization super-resolution microscopy was carried out. This enabled the visualization of the cytoskeletons at nanoscale resolution\, revealing highly complex organization. Second\, novel computational approaches were developed for the quantitative analysis of the highly entangled cytoskeletal networks from super-resolution images. This enabled automated high-throughput analysis of the cytoskeletal filaments from complex images. These advances were demonstrated in the studies of microtubule network organization downstream of the small GTPase Rac1\, and the Sertoli cell cortical F-actin network organization downstream of the actin polymerization factors\, mDia1 and mDia3.  \n*All except panel are excused for closed-door examination*
URL:https://www.mbi.nus.edu.sg/event/topological-analysis-of-cytoskeletal-networks-from-single-molecule-localization-microscopy-images-by-zhang-zhen-kanchanawong-group/
LOCATION:MBI Seminar Room Lvl 5\, T-Lab\, Level 5\, 5A Engineering Drive 1\, Mechanobiology Institute\, National University of Singapore\, 117411\, Singapore
CATEGORIES:PhD Oral Defense
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Shanghai:20171208T093000
DTEND;TZID=Asia/Shanghai:20171208T103000
DTSTAMP:20260408T111601
CREATED:20171204T070742Z
LAST-MODIFIED:20171204T070814Z
UID:21451-1512725400-1512729000@www.mbi.nus.edu.sg
SUMMARY:CD74\, invariant chain\, a modulator of endosomal maturation and potential cancer immunotherapy vaccine by Prof Oddmund Bakke\, University of Oslo
DESCRIPTION:MBI Weekly Meeting Seminar\nTime: 9.30am – 10.30am\nDate: Friday\, 8 December 2017\nVenue: Level 5 Seminar Room\, T-Lab \nCD74\, invariant chain\, a modulator of endosomal maturation and potential cancer immunotherapy vaccine\nby Prof. Oddmund Bakke from University of Oslo \n 
URL:https://www.mbi.nus.edu.sg/event/cd74-invariant-chain-a-modulator-of-endosomal-maturation-and-potential-cancer-immunotherapy-vaccine-by-prof-oddmund-bakke-university-of-oslo/
LOCATION:MBI Seminar Room Lvl 5\, T-Lab\, Level 5\, 5A Engineering Drive 1\, Mechanobiology Institute\, National University of Singapore\, 117411\, Singapore
CATEGORIES:MBI Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Shanghai:20171208T160000
DTEND;TZID=Asia/Shanghai:20171208T170000
DTSTAMP:20260408T111601
CREATED:20171201T053758Z
LAST-MODIFIED:20171201T053758Z
UID:21388-1512748800-1512752400@www.mbi.nus.edu.sg
SUMMARY:Improving AFM reveals a multitude of hidden dynamics in the unfolding of a membrane protein by Prof Thomas Perkins
DESCRIPTION:I am pleased to inform you on the seminar Prof Thomas Perkins (hosted by Prof Yan Jie) “Improving AFM reveals a multitude of hidden dynamics in the unfolding of a membrane protein” on 8 Dec@4pm at T-Lab Level 5 Seminar Rooms. Thank you.
URL:https://www.mbi.nus.edu.sg/event/improving-afm-reveals-a-multitude-of-hidden-dynamics-in-the-unfolding-of-a-membrane-protein-by-prof-thomas-perkins/
LOCATION:MBI Seminar Room Lvl 5\, T-Lab\, Level 5\, 5A Engineering Drive 1\, Mechanobiology Institute\, National University of Singapore\, 117411\, Singapore
CATEGORIES:MBI Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20171209
DTEND;VALUE=DATE:20171210
DTSTAMP:20260408T111601
CREATED:20170607T072153Z
LAST-MODIFIED:20170607T072153Z
UID:19640-1512777600-1512863999@www.mbi.nus.edu.sg
SUMMARY:Fall academic semester ends
DESCRIPTION:Fall academic semester ends. Full NUS Academic Calender here.
URL:https://www.mbi.nus.edu.sg/event/fall-academic-semester-ends/
LOCATION:National University of Singapore
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20171209
DTEND;VALUE=DATE:20171210
DTSTAMP:20260408T111601
CREATED:20171023T013241Z
LAST-MODIFIED:20171205T052241Z
UID:20939-1512777600-1512863999@www.mbi.nus.edu.sg
SUMMARY:9 Dec 2017: MBI-UPenn Joint Symposium
DESCRIPTION:Programme\nMBI-UPenn Joint Symposium\n  \n  \n Download Program \n Download Abstract Book \n \n 
URL:https://www.mbi.nus.edu.sg/event/mbi-upenn-joint-symposium/
LOCATION:MBI Seminar Room Lvl 5\, T-Lab\, Level 5\, 5A Engineering Drive 1\, Mechanobiology Institute\, National University of Singapore\, 117411\, Singapore
CATEGORIES:Symposium
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20171211
DTEND;VALUE=DATE:20171215
DTSTAMP:20260408T111601
CREATED:20170306T085107Z
LAST-MODIFIED:20171124T085925Z
UID:17473-1512950400-1513295999@www.mbi.nus.edu.sg
SUMMARY:3rd International Symposium on Mechanobiology
DESCRIPTION:3rd International Symposium on Mechanobiology\, Singapore\n11-14 December 2017\nU-Town\, National University of Singapore\nThe 3rd International Symposium on Mechanobiology is being organized by the Mechanobiology  Institute\, National University of Singapore. \nThis Symposium is the third in a series of scientific meetings supported and endorsed by the International Society of Mechanobiology\, the first two being held in Shanghai and Okayama respectively. This symposium aims to cover the fundamentals\, recent advances and emerging issues related to mechanobiology.  It will provide a unique opportunity to advance knowledge and understanding in the areas of basic and applied research in mechanobiology. This field involves interdisciplinary approaches combining biology with mechanics/physics as well as experimental techniques and  computational modelling.  In addition\, mechanobiology has also increasingly been involved in the study of a plethora of biological and pathological processes\, including development\, aging\, infection as well as diseases such as cancer. A wide spectrum of these aspects across multiscales from the molecular\, cellular\, tissue to the organ level will be covered in this Symposium. The topics include: \n1.     Molecular biomechanics\n2.     Cellular mechanics\n3.     Nuclear mechanics\n4.     Tissue mechanics\n5.     Organ mechanics\n6.     Cytoskeletal dynamics\n7.     Mechanosensitive channels\n8.     Mechanosensing and mechanosignaling\n9.     Cell Migration\n10.  Matrix assembly and remodeling\n11.  Adhesion site assembly and dynamics\n12.  Mechanobiology of Diseases\n13.  Bacterial-host interactions and pathogenesis\n14.  Skin mechanobiology\n15.  Mechanomedicine\n16.  Nano/Microfabrication\n17.  Nano/Microfluidics\n18.  Tools & Techniques in mechanobiology\n19.  Microscopy\n20.  Computational and theoretical modeling\n21.  Bio- and biomimetic materials\n22.  Tissue engineering and regenerative medicine\n23.  Synthetic biology\n24.  Immuno-mechanobiology \nInternational Scientific Committee\n1. Taiji Adachi\, Kyoto University\, Japan\n2. Joji Ando\, Dokkyo Medical School\, Japan\n3. Shu Chien (Co-chair)\, University of California\, San Diego\, USA\n4. Linhong Deng (Co-chair)\, Changzhou University\, China\n5. Denis Discher\, University of Pennsylvania\, USA\n6. Wojciech Dzwolak\, University of Warsaw\, Poland\n7. David Elad\, Tel Aviv University\, Israel\n8. Edward Guo\, Columbia University\, USA\n9. Guy Genin\, Washington University in St. Louis\, USA\n10. Shigeo Hayashi\, RIKEN Center for Developmental Biology\, Japan\n11. Jonathan Howard\, Yale University\, USA\n12. Shin’ichi Ishiwata\, Waseda University\, Japan\n13. Roger Kamm\, Massachusetts Institute of Technology\, USA\n14. Michael King\, Vanderbilt University\,USA\n15. C.T. Lim\, Mechanobiology Institute\,  National University of Singapore\, Singapore\n16. Mian Long\, Chinese Academy of Sciences\, China\n17. Boris Martinac (Co-chair)\, Victor Chang Cardiac Research Institute\, Australia\n18. Satyajit Mayor\, National Centre for Biological Sciences\, India\n19. Daniel Mueller\, ETH Zurich\, Switzerland\n20. Keiji Naruse\, Okayama University\, Japan\n21. Alphonso Ngan\, University of Hong Kong\, Hong Kong\n22. Toshihiko Ogura\, Tohoku University\, Japan\n23. Toshiro Ohashi\, Osaka University\, Japan\n24. Matthieu Piel (Co-chair)\, Institut Curie\, France\n25. Michael Sheetz (Chair)\,Mechanobiology Institute\, National University of Singapore\n26. Masahiro Sokabe (Co-chair)\, Nagoya University\, Japan\n27. G.V. Shivashankar\, Mechanobiology Institute\, National University of Singapore\n28. Vivek Shenoy\, University of Pennsylvania\, USA\n29. Sam Safran\, Weizmann Institute\, Israel\n30. Ulrich Schwarz\,University of Heidelburg\, Germany\n31. Ming-Jer Tang\, National Cheng Kung University\, Taiwan\n32. Peter Wang\, University of Californaia\, San Diego\, USA\n33. David Weitz\, Harvard University\, USA\n34. Ken Yamada\, Laboratory of Cell and Developmental Biology\, NIH\, USA\n35. Xiaoqiang Yao\, Chinese University of Hong Kong\, Hong Kong\n36. Alpha Yap\, University of Queensland\, Australia\n37. Shi Yongde\, Shanghai Medical School\, China\n38. Xiaohui (Frank) Zhang\, Lehigh University\, USA\n39. Cheng Zhu\, Georgia Institute of Technology\, USA \nOrganizing Committee\n1. Low Boon Chuan\, Mechanobiology Institute\, NUS\, Singapore\n2. Yan Jie (Scientific Program Chair)\, Mechanobiology Institute\, NUS\, Singapore\n3. Tony Pakorn Kanchanawong\, Mechanobiology Institute\, NUS\, Singapore\n4. C.T Lim (Chair)\, Mechanobiology Institute\, NUS\, Singapore\n5. Wu Min (Scientific Program Co-chair) Mechanobiology Institute\, NUS\, Singapore\n6. G.V.Shivashankar (Co-chair)\, Mechanobiology Institute\, NUS\, Singapore\n7. Timothy Saunders\, Mechanobiology Institute\, NUS\, Singapore\n8. Yusuke Toyama\, Mechanobiology Institute\, NUS\, Singapore \nConference Secretariat\nLatha K.S\, Conference Administrator\, Mechanobiology Institute\, NUS\, Singapore \nVenue\nUniversity Town\nNational University of Singapore\nSingapore \nRegistrations\nRegistrations and online submission of abstracts will be open shortly. \nInterested applicants may register online for the conference by filling in the online registration form and submitting an abstract in about 200 words. \nKindly note the deadlines for registration and abstract submission: \n\n\n\nRegistration & Abstract submission (Early Bird ends)\n\n 15 July 2017\n\n\nRegistration & Abstract Submission (late submission ends)\n\n 15 August 2017\n\n\nNotification of Acceptance\n\n8  September 2017\n\n\n\nSelected applicants are required to pay the registration fees as shown below. Please note that all presenters (both oral & posters) are required to pay the registration fees. \n\n\n\nStudents (no banquet)\n\n S$\n\n\nEarly Bird Registration\n\n 300\n\n\nLate  registration\n\n 350\n\n\nOn-site registration\n\n 400\n\n\nOthers\n\n\n\n\nEarly Bird Registration\n\n 650\n\n\nLate  registration\n\n 750\n\n\n On-site registration\n\n 800\n\n\n\nStudent Fees\nTo register as a student\, proof of your student status needs to be furnished. The student identification card or a letter from your university needs to be uploaded during the registration process. If the same cannot be uploaded please email it to ismb2017@gmail.com with your name and the reference of your registration. The registration fee for students does not cover the conference banquet. \nPayment of Registration Fees\nPayment can be made on the online registration payment portal by means of credit card only once you receive the notification of acceptance. \nDeadline\nThe last date for payment of registration fee for online registrations is September 30\, 2017. \nHousing\nA certain number of non-AC(student accommodation ) and a very limited of AC accommodation(student accommodation)  have been reserved on campus for the participants of the conference on payment basis strictly from the 10th December to 15th December (5 nights only). Once the notification of acceptance is received\, the participants will have to book the accommodation directly with the Office of Housing and making the payment for the accommodation at the time of booking. Further details on the room rates and whom to contact will be up on the website at a later date. \nContracted Housing\nFor participants who do not wish to book the campus housing\, the following hotel close to NUS campus will be  providing discounted rates for the conference. More information and the booking details will be provided shortly. \nPark Avenue Rochester\n31 Rochester Drive\nSingapore\, 138637\nPhone: (65) 6808 8600\nGoogle Map\nHotel Website: www.parkavenuerochester.com \nCancellation Policy\nNotification of cancellation must be submitted by email to the conference organizers to ismb2017@gmail.com \nCancellation made before October 31\, 2017 – Refund of registration fee paid less administration fee of SGD 100 \nCancellation made before November 15\, 2017 – Refund of 50% of registration fees \nCancellations made after November 15 2017 will NOT be refunded \nNo shows will NOT be refunded \nVisa\nPlease ensure that you have a valid passport for travel and check with your local Embassy. Please note that some countries require your passport to be valid for up to six months. \nNationals from a wide majority of countries do not require visas for social visits of a 30 day duration provided that they are in possession of recognized and valid travel  documents\, adequate funds and return tickets. For a list of countries whose nationals require visa to travel to Singapore\, please refer to http://www.ica.gov.sg/page.aspx?pageid=96. \nShould an official letter of invitation and V39A form be required for your visa\, please send your request by email to ismb2017@gmail.com once the conference registration formalities are completed with the payment of registration fees. \nIf your visa is declined\, refunds will be offered in line with our cancellation policy. \nSponsorship\nWe hope to attract about 300 participants from all parts of the world. This event provides an excellent opportunity to show-case the latest products and technologies available to researchers and provide marketing opportunities to companies. Interested sponsors may please write to ismb2017@gmail.com or to Prof.C.T.Lim at ctlim@nus.edu.sg.
URL:https://www.mbi.nus.edu.sg/event/11-14-dec-2017-the-3rd-international-symposium-on-mechanobiology-singapore-2017/
LOCATION:CREATE Tower\, NUS University Town\, 1 Create Way\, Singapore\, 138602\, Singapore
CATEGORIES:Conference
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Shanghai:20171215T160000
DTEND;TZID=Asia/Shanghai:20171215T170000
DTSTAMP:20260408T111601
CREATED:20171212T052923Z
LAST-MODIFIED:20171212T052923Z
UID:21580-1513353600-1513357200@www.mbi.nus.edu.sg
SUMMARY:Self-Organization Of Clathrin Mediated Endocytosis Into Spatiotemporal Waves And The Onset Of Cortical Patterning  by Yang Yang
DESCRIPTION:MBI PhD Oral Defense\nTime: 4pm-5pm\nDate: Friday\, 15 December 2017\nVenue: MBI\, level 5 meeting rooms\nSupervisor:  Professor Wu Min \nSelf-Organization Of Clathrin Mediated Endocytosis Into Spatiotemporal Waves And The Onset Of Cortical Patterning\nby Yang Yang\, Wu Min Group \nAssembly of the endocytic machinery is a constitutively active process that is important for the organization of the plasma membrane\, signal transduction\, and membrane trafficking. Existing research has focused on the stochastic nature of endocytosis. Here\, we report the emergence of the collective dynamics of endocytic proteins as periodic traveling waves. Coordinated clathrin assembly provides the earliest spatial cue for cortical waves and sets the direction of propagation. Surprisingly\, the onset of clathrin waves\, but not individual endocytic events\, requires feedback from downstream factors\, including FBP17\, Cdc42\, and N-WASP\, and intermediate phosphatidylinositol-3\,4\,5-trisphosphate (PIP3) level as a determinant of such feedback.  In addition to the localized endocytic assembly at the plasma membrane\, intracellular clathrin and phosphatidylinositol-3\,4-bisphosphate (PI(3\,4)P2) predict the excitability of the plasma membrane and modulate the geometry of traveling waves. Moreover\, for further understanding of the biological function of endocytic waves\, we identified cargoes that are specific to the wave-related endocytic pathway through SILAC assay. \n**Please note the examination following the seminar is closed-door**
URL:https://www.mbi.nus.edu.sg/event/self-organization-of-clathrin-mediated-endocytosis-into-spatiotemporal-waves-and-the-onset-of-cortical-patterning-by-yang-yang/
LOCATION:MBI Seminar Room Lvl 5\, T-Lab\, Level 5\, 5A Engineering Drive 1\, Mechanobiology Institute\, National University of Singapore\, 117411\, Singapore
CATEGORIES:PhD Oral Defense
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Shanghai:20171219T093000
DTEND;TZID=Asia/Shanghai:20171219T103000
DTSTAMP:20260408T111601
CREATED:20171213T012557Z
LAST-MODIFIED:20171213T013102Z
UID:21584-1513675800-1513679400@www.mbi.nus.edu.sg
SUMMARY:MBI SPSS: A cross-talk between focal adhesion and microtubules by Yukako Nishimura
DESCRIPTION:MBI Student and Postdoc Seminar Series (SPSS)\n\nTime: 9.30am-10.30am\nDate: Tuesday\, 19 December\, 2017\nVenue: Level 5 Seminar Room\, T-Lab\n \n\nA cross-talk between focal adhesion and microtubules\nby Yukako Nishimura\, Bershadsky Group \n  \n*Please note this event is limited to MBI researchers and invited guests only. Thank you*
URL:https://www.mbi.nus.edu.sg/event/a-cross-talk-between-focal-adhesion-and-microtubules-by-yukako-nishimura/
LOCATION:MBI Seminar Room Lvl 5\, T-Lab\, Level 5\, 5A Engineering Drive 1\, Mechanobiology Institute\, National University of Singapore\, 117411\, Singapore
CATEGORIES:MBI Student & Postdoc Seminar
END:VEVENT
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