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X-WR-CALNAME:Mechanobiology Institute, National University of Singapore
X-ORIGINAL-URL:https://www.mbi.nus.edu.sg
X-WR-CALDESC:Events for Mechanobiology Institute, National University of Singapore
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BEGIN:VTIMEZONE
TZID:Asia/Shanghai
BEGIN:STANDARD
TZOFFSETFROM:+0800
TZOFFSETTO:+0800
TZNAME:CST
DTSTART:20160101T000000
END:STANDARD
END:VTIMEZONE
BEGIN:VEVENT
DTSTART;TZID=Asia/Shanghai:20170303T093000
DTEND;TZID=Asia/Shanghai:20170303T103000
DTSTAMP:20260628T001255
CREATED:20170224T035821Z
LAST-MODIFIED:20170224T035821Z
UID:17299-1488533400-1488537000@www.mbi.nus.edu.sg
SUMMARY:MBI Seminar: Sculpting the ring to make a cut: contractile ring structure and mechanism of cell division by Dr Mithilesh Mishra
DESCRIPTION:We are pleased to inform you on the Seminar by Dr Mithilesh Mishra from Tata Institute of Fundamental Research titled “Sculpting the ring to make a cut: contractile ring structure and mechanism of cell division”\, on Friday 3 March 2017 at 9:30am at T-Lab Level 5 Seminar Rooms. \nHost: A/Prof Ronen Zaidel-Bar \n \nBrief CV \nDr Mithilesh Mishra is currently an Assistant Professor at the Tata Institute of Fundamental Research.  His group is interested in understanding the mechanism underlying the process of cell division and its regulation. They use a combination of in vitro and in vivo approaches including genetic\, cellular\, molecular and mathematical approaches to understand the assembly and function of the cell division apparatus. \nWebsite:  http://www.tifr.res.in/~dbs/faculty/M_Mishra.html \nAll are welcome.
URL:https://www.mbi.nus.edu.sg/event/mbi-seminar-sculpting-the-ring-to-make-a-cut-contractile-ring-structure-and-mechanism-of-cell-division-by-dr-mithilesh-mishra/
LOCATION:National University of Singapore
CATEGORIES:MBI Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Shanghai:20170306T120000
DTEND;TZID=Asia/Shanghai:20170306T130000
DTSTAMP:20260628T001255
CREATED:20170301T061600Z
LAST-MODIFIED:20170301T061600Z
UID:17388-1488801600-1488805200@www.mbi.nus.edu.sg
SUMMARY:Dept Biochemistry Seminar: Super-resolution imaging of Salmonella SPI-2 regulation: a view from 30\,000 feet to 20nm by Prof Linda Kenney
DESCRIPTION:
URL:https://www.mbi.nus.edu.sg/event/dept-biochemistry-seminar-super-resolution-imaging-of-salmonella-spi-2-regulation-a-view-from-30000-feet-to-20nm-by-prof-linda-kenney/
LOCATION:National University of Singapore
CATEGORIES:Dept of Biochemistry
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Shanghai:20170306T160000
DTEND;TZID=Asia/Shanghai:20170306T170000
DTSTAMP:20260628T001255
CREATED:20170210T062319Z
LAST-MODIFIED:20170210T062604Z
UID:17005-1488816000-1488819600@www.mbi.nus.edu.sg
SUMMARY:MBI Seminar: Microfabricated Tissues for Medical Discovery and Therapy by Dr Zhang Boyang
DESCRIPTION:  \nAbout the Speaker\nBoyang Zhang is a postdoctoral fellow at University of Toronto and a co-founder of TARA Biosystems. At TARA\, Dr. Zhang is developing the manufacturing process of Biowire TM plates. Dr. Zhang obtained his B.Eng. in Chemical and Biomolecular Engineering from Georgia Institute of Technology in 2010\, and his Ph.D. in Chemical Engineering and Applied Chemistry from University of Toronto in 2016. \nIn 2016 Dr. Zhang was named MedTech’s Rising Star by Medical Device and Diagnostic Industry (MD+DI). In 2013\, University of Toronto named Dr. Zhang inventor of the year for his collaborative work on a skin bioprinter. Dr. Zhang’s research interests are tissue vascularization\, tissue assembly and organ-in-a-dish engineering. He utilizes microfabrication techniques in combination with biomaterials to build complex tissue models in vitro for drug discovery and regenerative medicine. His research on AngioChip\, published as a cover article in Nature Materials\, was featured in the Toronto Star and on The National on CBC in 2016. He has published over 20 research papers with H-index of 10 and has 3 patents pending.
URL:https://www.mbi.nus.edu.sg/event/mbi-seminar-microfabricated-tissues-for-medical-discovery-and-therapy-by-dr-zhang-boyang/
LOCATION:MBI Seminar Room Lvl 5\, T-Lab\, Level 5\, 5A Engineering Drive 1\, Mechanobiology Institute\, National University of Singapore\, 117411\, Singapore
CATEGORIES:MBI Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Shanghai:20170306T163000
DTEND;TZID=Asia/Shanghai:20170306T173000
DTSTAMP:20260628T001255
CREATED:20170227T070549Z
LAST-MODIFIED:20170227T070624Z
UID:17353-1488817800-1488821400@www.mbi.nus.edu.sg
SUMMARY:BIGHEART Seminar: Breaking Bad: Dissembling Pathogenic Biofilms for Better Treatment Efficacy by Dr Song Lin Chua
DESCRIPTION:
URL:https://www.mbi.nus.edu.sg/event/bigheart-seminar-breaking-bad-dissembling-pathogenic-biofilms-for-better-treatment-efficacy-by-dr-song-lin-chua-2/
LOCATION:BIGHEART Seminar\, CeLS Seminar Room 1\, Singapore\, 117456\, Singapore
CATEGORIES:Biomedical Institute for Global Health Research & Technology (BIGHEART)
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Shanghai:20170307T093000
DTEND;TZID=Asia/Shanghai:20170307T100000
DTSTAMP:20260628T001255
CREATED:20170306T061340Z
LAST-MODIFIED:20170306T061340Z
UID:17457-1488879000-1488880800@www.mbi.nus.edu.sg
SUMMARY:MBI SPSS: Investigating dynamics of bile canaliculi in physiological conditions and obstructive cholestasis by Kapish Gupta
DESCRIPTION:Please be informed of SPSS Meeting Seminar @ 9.30am on 7 March at Level 5 Seminar Room. \nPresenter 1: Kapish Gupta\nTalk Title : Investigating dynamics of bile canaliculi in physiological conditions and obstructive cholestasis \nPresenter 2: Hayri Emrah Balcioglu\nTalk Title: Effect of substrate stiffness on collective cell behaviour
URL:https://www.mbi.nus.edu.sg/event/mbi-spss-investigating-dynamics-of-bile-canaliculi-in-physiological-conditions-and-obstructive-cholestasis-by-kapish-gupta/
LOCATION:MBI Seminar Room Lvl 5\, T-Lab\, Level 5\, 5A Engineering Drive 1\, Mechanobiology Institute\, National University of Singapore\, 117411\, Singapore
CATEGORIES:MBI Student & Postdoc Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Shanghai:20170307T100000
DTEND;TZID=Asia/Shanghai:20170307T103000
DTSTAMP:20260628T001255
CREATED:20170306T061446Z
LAST-MODIFIED:20170306T061446Z
UID:17459-1488880800-1488882600@www.mbi.nus.edu.sg
SUMMARY:MBI SPSS: Effect of substrate stiffness on collective cell behaviour by Hayri Emrah Balcioglu
DESCRIPTION:Please be informed of SPSS Meeting Seminar @ 9.30am on 7 March at Level 5 Seminar Room. \nPresenter 1: Kapish Gupta\nTalk Title : Investigating dynamics of bile canaliculi in physiological conditions and obstructive cholestasis \nPresenter 2: Hayri Emrah Balcioglu\nTalk Title: Effect of substrate stiffness on collective cell behaviour
URL:https://www.mbi.nus.edu.sg/event/mbi-spss-effect-of-substrate-stiffness-on-collective-cell-behaviour-by-hayri-emrah-balcioglu/
LOCATION:MBI Seminar Room Lvl 5\, T-Lab\, Level 5\, 5A Engineering Drive 1\, Mechanobiology Institute\, National University of Singapore\, 117411\, Singapore
CATEGORIES:MBI Student & Postdoc Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Shanghai:20170307T140000
DTEND;TZID=Asia/Shanghai:20170307T150000
DTSTAMP:20260628T001255
CREATED:20170227T033539Z
LAST-MODIFIED:20170227T070739Z
UID:17348-1488895200-1488898800@www.mbi.nus.edu.sg
SUMMARY:BIGHEART Seminar: Application of Single-particle Tracking and Manipulation Techniques to Study Mechanochemical Protein Complexes by Dr Artem Yefremov
DESCRIPTION:
URL:https://www.mbi.nus.edu.sg/event/bigheart-seminar-breaking-bad-dissembling-pathogenic-biofilms-for-better-treatment-efficacy-by-dr-song-lin-chua/
LOCATION:BIGHEART Seminar\, CeLS Seminar Room 1\, Singapore\, 117456\, Singapore
CATEGORIES:Biomedical Institute for Global Health Research & Technology (BIGHEART)
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Shanghai:20170307T160000
DTEND;TZID=Asia/Shanghai:20170307T170000
DTSTAMP:20260628T001255
CREATED:20170217T052141Z
LAST-MODIFIED:20170217T052141Z
UID:17163-1488902400-1488906000@www.mbi.nus.edu.sg
SUMMARY:Modulating scaffold architecture\, mechanics and growth factor presentation for cartilage tissue engineering by Aditya Arora
DESCRIPTION:
URL:https://www.mbi.nus.edu.sg/event/modulating-scaffold-architecture-mechanics-and-growth-factor-presentation-for-cartilage-tissue-engineering-by-aditya-arora/
LOCATION:MBI Seminar Room Lvl 5\, T-Lab\, Level 5\, 5A Engineering Drive 1\, Mechanobiology Institute\, National University of Singapore\, 117411\, Singapore
CATEGORIES:MBI Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170308
DTEND;VALUE=DATE:20170311
DTSTAMP:20260628T001255
CREATED:20170213T075645Z
LAST-MODIFIED:20170309T015221Z
UID:17069-1488931200-1489190399@www.mbi.nus.edu.sg
SUMMARY:2D and 3D Photopatterning of Proteins & Microfabrication with PRIMO
DESCRIPTION:  \n \nAlvéole and the Mechanobiology Institute\, National University of Singapore (MBI) invite you to a workshop on 2D and 3D Proteins Photopatterning and Microfabrication possibilities offered with PRIMO which will be held at the MechanoBiology Institute at NUS from March 8 to 10\, 2017. \nThe program will be the same for all 3 days so you can pick the date which suits you best without missing anything. \nIn this workshop\, we will present a new UV-based technology for multiple protein micro-patterning – PRIMO –  and its applications in cell micro-patterning and in micro-fabrication. \nAll afternoons will be dedicated to free experimenting time to allow you to test this technology on your own project of experiment. \nIn order to best prepare the experiments\, we kindly ask you to inform us of the substrate\, protein and pattern you would like to test. \nKindly register providing your preferred date of attendance and your topic of interest by emailing to marie-charlotte.manus@alveolelab.com
URL:https://www.mbi.nus.edu.sg/event/2d-and-3d-photopatterning-of-proteins-microfabrication-with-primo/
LOCATION:MBI Seminar Room Lvl 5\, T-Lab\, Level 5\, 5A Engineering Drive 1\, Mechanobiology Institute\, National University of Singapore\, 117411\, Singapore
CATEGORIES:Workshop
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Shanghai:20170313T140000
DTEND;TZID=Asia/Shanghai:20170313T150000
DTSTAMP:20260628T001255
CREATED:20170308T013126Z
LAST-MODIFIED:20170308T013126Z
UID:17482-1489413600-1489417200@www.mbi.nus.edu.sg
SUMMARY:PhD Oral Defense: Molecular mechanisms underlying DNA replication by GUO Shiwen
DESCRIPTION:Molecular mechanisms underlying DNA replication\nSpeaker          :   GUO Shiwen (Graduate Student\, MBI\, NUS) \nDate                :   13 Mar 2017\, Monday \nTime                :   2pm \nVenue             :   MBI\, level 5 seminar rooms \nSupervisor(s)  :  Prof YAN Jie \nAbstract: The DNA replisome is a highly organized integrity with great efficiency and accuracy. In DNA replication\, primase is a key enzyme to initiate the synthesis of new DNA strand by priming a short RNA oligomer on parental single stranded DNA (ssDNA). After that\, DNA replication proceeds with classical DNA polymerases like polymerase \, and . It has been known that these DNA polymerases are sensitive to various obstacles such as DNA damage lesions or DNA secondary structures. As a result\, these obstacles lead to replication stress that may cause replication fork stalling and potential collapse. Members of archaeo-eukaryotic primases (AEPs) are necessary to initiate DNA replication and prevent replication fork stalling in archaea and eukarya. In my PhD thesis\, I aim to study the mechanisms of the only two human AEPs that have been identified up to date: primase that initiates the replication\, and PrimPol that prevents replication fork stalling. My studies will be mainly based on single-molecule technologies. I envision that these explorations will provide important novel insights into the mechanisms associated with the functions of the two AEPs at a single-molecule level. \n  \nALL EXCEPT PANEL ARE EXCUSED FOR CLOSE DOOR EXAMINATION
URL:https://www.mbi.nus.edu.sg/event/phd-oral-defense-molecular-mechanisms-underlying-dna-replication-by-guo-shiwen/
LOCATION:MBI Seminar Room Lvl 5\, T-Lab\, Level 5\, 5A Engineering Drive 1\, Mechanobiology Institute\, National University of Singapore\, 117411\, Singapore
CATEGORIES:PhD Oral Defense
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Shanghai:20170314T093000
DTEND;TZID=Asia/Shanghai:20170314T100000
DTSTAMP:20260628T001255
CREATED:20170308T055312Z
LAST-MODIFIED:20170308T055312Z
UID:17487-1489483800-1489485600@www.mbi.nus.edu.sg
SUMMARY:MBI SPSS: Uncovering the unique transcriptional signatures of the mechanosensitive proteins YAP and TAZ by Megan Finch-Edmondson
DESCRIPTION:Please be informed of SPSS Meeting Seminar @ 9.30am on 14 March at Level 5 Seminar Room. \nPresenter 1: Megan Finch-Edmondson \nTalk Title: Uncovering the unique transcriptional signatures of the mechanosensitive proteins YAP and TAZ \nPresenter 2:Christopher Amourda \nTalk Title: Au Bonheur des Dames … et des Mouches
URL:https://www.mbi.nus.edu.sg/event/mbi-spss-uncovering-the-unique-transcriptional-signatures-of-the-mechanosensitive-proteins-yap-and-taz-by-megan-finch-edmondson/
LOCATION:MBI Seminar Room Lvl 5\, T-Lab\, Level 5\, 5A Engineering Drive 1\, Mechanobiology Institute\, National University of Singapore\, 117411\, Singapore
CATEGORIES:MBI Student & Postdoc Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Shanghai:20170314T100000
DTEND;TZID=Asia/Shanghai:20170314T103000
DTSTAMP:20260628T001255
CREATED:20170308T055423Z
LAST-MODIFIED:20170308T055423Z
UID:17489-1489485600-1489487400@www.mbi.nus.edu.sg
SUMMARY:MBI SPSS: Au Bonheur des Dames ... et des Mouches by Christopher Amourda
DESCRIPTION:Please be informed of SPSS Meeting Seminar @ 9.30am on 14 March at Level 5 Seminar Room. \nPresenter 1: Megan Finch-Edmondson \nTalk Title: Uncovering the unique transcriptional signatures of the mechanosensitive proteins YAP and TAZ \nPresenter 2: Christopher Amourda \nTalk Title: Au Bonheur des Dames … et des Mouches
URL:https://www.mbi.nus.edu.sg/event/mbi-spss-au-bonheur-des-dames-et-des-mouches-by-christopher-amourda/
LOCATION:MBI Seminar Room Lvl 5\, T-Lab\, Level 5\, 5A Engineering Drive 1\, Mechanobiology Institute\, National University of Singapore\, 117411\, Singapore
CATEGORIES:MBI Student & Postdoc Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Shanghai:20170314T160000
DTEND;TZID=Asia/Shanghai:20170314T170000
DTSTAMP:20260628T001255
CREATED:20170303T033512Z
LAST-MODIFIED:20170303T033650Z
UID:17414-1489507200-1489510800@www.mbi.nus.edu.sg
SUMMARY:Cell-Matrix Interactions in Fibrosis and Cancer: Multiscale Mechano-Chemical Models by Prof Vivek Shenoy
DESCRIPTION:
URL:https://www.mbi.nus.edu.sg/event/cell-matrix-interactions-in-fibrosis-and-cancer-multiscale-mechano-chemical-models-by-prof-vivek-shenoy/
LOCATION:MBI Seminar Room Lvl 5\, T-Lab\, Level 5\, 5A Engineering Drive 1\, Mechanobiology Institute\, National University of Singapore\, 117411\, Singapore
CATEGORIES:MBI Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Shanghai:20170317T093000
DTEND;TZID=Asia/Shanghai:20170317T103000
DTSTAMP:20260628T001255
CREATED:20170316T235118Z
LAST-MODIFIED:20170316T235118Z
UID:17568-1489743000-1489746600@www.mbi.nus.edu.sg
SUMMARY:Revealing how cells decide their fate\, shape and position in vivo by Dr Melanie D White
DESCRIPTION:
URL:https://www.mbi.nus.edu.sg/event/revealing-how-cells-decide-their-fate-shape-and-position-in-vivo-by-dr-melanie-d-white/
LOCATION:MBI Seminar Room Lvl 5\, T-Lab\, Level 5\, 5A Engineering Drive 1\, Mechanobiology Institute\, National University of Singapore\, 117411\, Singapore
CATEGORIES:MBI Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Shanghai:20170320T110000
DTEND;TZID=Asia/Shanghai:20170320T120000
DTSTAMP:20260628T001255
CREATED:20170308T100519Z
LAST-MODIFIED:20170308T100519Z
UID:17546-1490007600-1490011200@www.mbi.nus.edu.sg
SUMMARY:A*STAR IMB: Rethinking Skin and Muscle Function by Dr Jens Marc Titze
DESCRIPTION:
URL:https://www.mbi.nus.edu.sg/event/astar-imb-rethinking-skin-and-muscle-function-by-dr-jens-marc-titze/
LOCATION:National University of Singapore
CATEGORIES:A*STAR Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Shanghai:20170321T093000
DTEND;TZID=Asia/Shanghai:20170321T100000
DTSTAMP:20260628T001256
CREATED:20170319T233816Z
LAST-MODIFIED:20170319T233816Z
UID:17571-1490088600-1490090400@www.mbi.nus.edu.sg
SUMMARY:MBI SPSS: Cell and Tissue Interaction in Shaping the Drosophila ventral Nerve Cord by Anand Pratap Singh
DESCRIPTION:Please be informed of SPSS Meeting Seminar @ 9.30am on 21 March at Level 5 Seminar Room. \nPresenter 1: Anand Pratap Singh\nTalk Title: Cell and Tissue Interaction in Shaping the Drosophila ventral Nerve Cord \nPresenter 2: Zhang Yue\nTalk Title: Investigating the structure and function of novel actin organization in polarized single hepatocyte \n 
URL:https://www.mbi.nus.edu.sg/event/mbi-spss-cell-and-tissue-interaction-in-shaping-the-drosophila-ventral-nerve-cord-by-anand-pratap-singh/
LOCATION:MBI Seminar Room Lvl 5\, T-Lab\, Level 5\, 5A Engineering Drive 1\, Mechanobiology Institute\, National University of Singapore\, 117411\, Singapore
CATEGORIES:MBI Student & Postdoc Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Shanghai:20170321T100000
DTEND;TZID=Asia/Shanghai:20170321T103000
DTSTAMP:20260628T001256
CREATED:20170319T233919Z
LAST-MODIFIED:20170319T233919Z
UID:17573-1490090400-1490092200@www.mbi.nus.edu.sg
SUMMARY:MBI SPSS: Investigating the structure and function of novel actin organization in polarized single hepatocyte by Zhang Yue
DESCRIPTION:Please be informed of SPSS Meeting Seminar @ 9.30am on 21 March at Level 5 Seminar Room. \nPresenter 1: Anand Pratap Singh\nTalk Title: Cell and Tissue Interaction in Shaping the Drosophila ventral Nerve Cord \nPresenter 2: Zhang Yue\nTalk Title: Investigating the structure and function of novel actin organization in polarized single hepatocyte
URL:https://www.mbi.nus.edu.sg/event/mbi-spss-investigating-the-structure-and-function-of-novel-actin-organization-in-polarized-single-hepatocyte-by-zhang-yue/
LOCATION:MBI Seminar Room Lvl 5\, T-Lab\, Level 5\, 5A Engineering Drive 1\, Mechanobiology Institute\, National University of Singapore\, 117411\, Singapore
CATEGORIES:MBI Student & Postdoc Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Shanghai:20170321T110000
DTEND;TZID=Asia/Shanghai:20170321T120000
DTSTAMP:20260628T001256
CREATED:20170301T061312Z
LAST-MODIFIED:20170301T061312Z
UID:17384-1490094000-1490097600@www.mbi.nus.edu.sg
SUMMARY:A*STAR Seminar: Mechanoprotein YAP in the Control of Epidermal Homeostasis and Skin Disease by  Dr Annemiek Beverdam
DESCRIPTION:
URL:https://www.mbi.nus.edu.sg/event/astar-seminar-mechanoprotein-yap-in-the-control-of-epidermal-homeostasis-and-skin-disease-by-dr-annemiek-beverdam/
LOCATION:National University of Singapore
CATEGORIES:A*STAR Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Shanghai:20170321T110000
DTEND;TZID=Asia/Shanghai:20170321T120000
DTSTAMP:20260628T001256
CREATED:20170308T013407Z
LAST-MODIFIED:20170308T013407Z
UID:17484-1490094000-1490097600@www.mbi.nus.edu.sg
SUMMARY:TLL Seminar: Mechanisms of Neuroblast Development in C. elegans by Dr Ou Guangshuo
DESCRIPTION:
URL:https://www.mbi.nus.edu.sg/event/tll-seminar-mechanisms-of-neuroblast-development-in-c-elegans-by-dr-ou-guangshuo/
LOCATION:National University of Singapore
CATEGORIES:Temasek Lifesciences Laboratory (TLL)
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20170322
DTEND;VALUE=DATE:20170325
DTSTAMP:20260628T001256
CREATED:20170105T025708Z
LAST-MODIFIED:20170105T025850Z
UID:16461-1490140800-1490399999@www.mbi.nus.edu.sg
SUMMARY:Australia-Singapore Partnership in Skin Cancer Biology: From Melanocytes to Melanoma Immunology and Inflammation of Skin Cancers Evolution and Maintenance of Epithelial Cancers
DESCRIPTION:
URL:https://www.mbi.nus.edu.sg/event/registration-open-australia-singapore-partnership-in-skin-cancer-biology/
LOCATION:National University of Singapore
CATEGORIES:Conference
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Shanghai:20170322T130000
DTEND;TZID=Asia/Shanghai:20170322T180000
DTSTAMP:20260628T001256
CREATED:20170224T035438Z
LAST-MODIFIED:20170224T035438Z
UID:17297-1490187600-1490205600@www.mbi.nus.edu.sg
SUMMARY:Microscopy Core Workshop: MBI NIS-Elements Image Analysis
DESCRIPTION:MBI Microscopy Core will be holding MBI NIS-Elements Image Analysis Workshop at MBI\, level 5 seminar room on 22 March 2017\, 1pm-6pm. You will learn data analysis using NIS-Elements software from Nikon application scientist\, Dr. Clement Khaw. The workshop will be a combination of lectures and hands-on sessions. \nFor registration\, please email hui ting (mbioht@nus.edu.sg) with the following details by 1 March.  After the closing date\, successful registrants will be notified. \nName :\nPI :\nEmail :\nMobile number :\nLaptop : Windows laptop/ Macbook with Windows OS/ Macbook without Windows OS (Please indicate the type of laptop that you will bring to the workshop) \nTopics\nOverview of NIS-Elements\n– Tips and tricks\n– Data import & export \nData measurement\n– Interactive measurement with ROI tools\n– Automatic measurement with thresholding tools \nData presentation
URL:https://www.mbi.nus.edu.sg/event/microscopy-core-workshop-mbi-nis-elements-image-analysis/
LOCATION:MBI Seminar Room Lvl 5\, T-Lab\, Level 5\, 5A Engineering Drive 1\, Mechanobiology Institute\, National University of Singapore\, 117411\, Singapore
CATEGORIES:MBI Microscopy Core
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Shanghai:20170322T140000
DTEND;TZID=Asia/Shanghai:20170322T170000
DTSTAMP:20260628T001256
CREATED:20170320T042259Z
LAST-MODIFIED:20170320T042259Z
UID:17580-1490191200-1490202000@www.mbi.nus.edu.sg
SUMMARY:PhD Oral Exam: Mechanical impact of apoptotic cell extrusion in neighbouring tissue
DESCRIPTION:PhD Qualifying Examination \nMechanical impact of apoptotic cell extrusion in neighbouring tissue\nSpeaker          :   YOW Ying Ming\, Ivan (Graduate Student\, MBI\, NUS)\nDate                :   22 Mar 2017\, Wednesday\nTime                :   2pm\nVenue             :   NUS\, E3-06-10 \nSupervisor(s)  :  Asst. Prof TOYAMA Yusuke \nAbstract: Apoptotic cell extrusion is an important mechanical process that forcibly pushes a dying cell out of a tissue monolayer by forces exerted from its neighbouring cells. Studies have shown forces from apoptotic cell extrusion are required for cell-sheet fusion in Drosophila embryos while modulation of tissue tension can regulate apoptotic cell extrusion. As such\, mechanical forces may be involved in the regulation of cell extrusion. However\, little is known how tension is regulated after cell extrusion and there has not been any report on how changes in tension can regulate the biochemical cascade in the neighbours of dying cell that may provide a feedback to regulate the cell extrusion process. \nIn this proposal\, we will first probe how tissue stress changes upon apoptotic cell extrusion (Aim 1). To understand how neighbouring cells may respond to signals from the dying cells\, we will elucidate how neighbouring cells respond biochemically to apoptosis through mechanics (Aim 2). Mechanosensitive molecules that exhibit nuclear translocation will first be explored and eventually we want to know whether this nuclear translocation is regulated through mechanical force. Another interesting\, unanswered question is what happens to neighbouring cells’ actin dynamics after completion of cell extrusion (Aim 3). We hypothesise that the changes in actin dynamics may be coupled with the changes in mechanical forces These may address the longstanding question of how a dying cell ‘sends’ signal to the neighbouring cells\, of which one will undergo compensatory cell division to maintain tissue homeostasis. \nWith these open questions in the field of research\, the research question I propose is ‘How apoptosis mechanically influence neighbouring cells’. \nALL EXCEPT PANEL ARE EXCUSED FOR CLOSE DOOR EXAMINATION
URL:https://www.mbi.nus.edu.sg/event/phd-oral-exam-mechanical-impact-of-apoptotic-cell-extrusion-in-neighbouring-tissue/
LOCATION:National University of Singapore
CATEGORIES:PhD Oral Defense
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Shanghai:20170324T093000
DTEND;TZID=Asia/Shanghai:20170324T103000
DTSTAMP:20260628T001256
CREATED:20170303T084941Z
LAST-MODIFIED:20170323T014704Z
UID:17454-1490347800-1490351400@www.mbi.nus.edu.sg
SUMMARY:MBI Seminar: In Vitro Vascularized Models for Metastatic Cancer by Prof Roger D Kamm
DESCRIPTION:
URL:https://www.mbi.nus.edu.sg/event/in-vitro-vascularized-models-for-metastatic-cancer-by-prof-roger-d-kamm/
LOCATION:MBI Seminar Room Lvl 5\, T-Lab\, Level 5\, 5A Engineering Drive 1\, Mechanobiology Institute\, National University of Singapore\, 117411\, Singapore
CATEGORIES:MBI Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Shanghai:20170327T100000
DTEND;TZID=Asia/Shanghai:20170327T110000
DTSTAMP:20260628T001256
CREATED:20170321T025253Z
LAST-MODIFIED:20170321T025253Z
UID:17602-1490608800-1490612400@www.mbi.nus.edu.sg
SUMMARY:MBI PhD Defense: Role of BNIP-2 scaffold protein in cardiomyocyte signaling and differentiation by Darren\, WONG Chen Pei
DESCRIPTION:PhD Qualifying Examination \nRole of BNIP-2 scaffold protein in cardiomyocyte signaling and differentiation\nSpeaker          :   Darren\, WONG Chen Pei (Graduate Student\, MBI\, NUS)\nDate                :   27 Mar 2017\, Monday\nTime                :   10am\nVenue             :   MBI\, level 5 meeting rooms \nSupervisor(s)  :  Prof LOW Boon Chuan (main supervisor) and Asst. Prof KANCHANAWONG Pakorn (co-supervisor) \nAbstract: Cardiovascular diseases is a leading cause of death while the human heart has limited regenerative potential. Lost cardiomyocytes are replaced by diseased myofibroblast which can recruit inflammatory cells and secret factors that modifies the extra cellular matrix of the heart. Altered rigidity can affect the function and  the limited regenerative stem cell populations in the heart. This study  aims at understanding  how cardiomyocyte differentiation can be modulated by BNIP-2\,  a versatile signaling scaffold protein in integrating mechanical signals to  the biochemical changes in these cells. Understanding the biochemical and mechanical factors that influence cardiomyocyte differentiation may  direct differentiation of stem cells to mature cardiomyocytes. \nALL EXCEPT PANEL ARE EXCUSED FOR CLOSE DOOR EXAMINATION
URL:https://www.mbi.nus.edu.sg/event/mbi-phd-defense-role-of-bnip-2-scaffold-protein-in-cardiomyocyte-signaling-and-differentiation-by-darren-wong-chen-pei/
LOCATION:MBI Seminar Room Lvl 5\, T-Lab\, Level 5\, 5A Engineering Drive 1\, Mechanobiology Institute\, National University of Singapore\, 117411\, Singapore
CATEGORIES:PhD Oral Defense
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Shanghai:20170327T160000
DTEND;TZID=Asia/Shanghai:20170327T170000
DTSTAMP:20260628T001256
CREATED:20170323T065115Z
LAST-MODIFIED:20170323T065115Z
UID:17722-1490630400-1490634000@www.mbi.nus.edu.sg
SUMMARY:MBI Seminar: Drosophila as a model for muscle-tendon interaction by Prabhat Tiwari
DESCRIPTION:
URL:https://www.mbi.nus.edu.sg/event/mbi-seminar-drosophila-as-a-model-for-muscle-tendon-interaction-by-prabhat-tiwari/
LOCATION:MBI Seminar Room Lvl 5\, T-Lab\, Level 5\, 5A Engineering Drive 1\, Mechanobiology Institute\, National University of Singapore\, 117411\, Singapore
CATEGORIES:MBI Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Shanghai:20170328T093000
DTEND;TZID=Asia/Shanghai:20170328T100000
DTSTAMP:20260628T001256
CREATED:20170322T060133Z
LAST-MODIFIED:20170322T061117Z
UID:17624-1490693400-1490695200@www.mbi.nus.edu.sg
SUMMARY:MBI SPSS: The organization and regulation of the actin cortex in mouse embryonic stem cells by Xia Shumin
DESCRIPTION:Please be informed of SPSS Meeting Seminar @ 9.30am on 28 March at Level 5 Seminar Room. \nPresenter 1: Xia Shumin\nTalk Title: The organization and regulation of the actin cortex in mouse embryonic stem cells \nPresenter 2: Yuki Yamanaka\nTalk Title: To be advised
URL:https://www.mbi.nus.edu.sg/event/mbi-spss-the-organization-and-regulation-of-the-actin-cortex-in-mouse-embryonic-stem-cells-by-xia-shumin/
LOCATION:MBI Seminar Room Lvl 5\, T-Lab\, Level 5\, 5A Engineering Drive 1\, Mechanobiology Institute\, National University of Singapore\, 117411\, Singapore
CATEGORIES:MBI Student & Postdoc Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Shanghai:20170328T100000
DTEND;TZID=Asia/Shanghai:20170328T103000
DTSTAMP:20260628T001256
CREATED:20170327T022032Z
LAST-MODIFIED:20170327T022032Z
UID:17744-1490695200-1490697000@www.mbi.nus.edu.sg
SUMMARY:MBI SPSS: Control of Needle Length and Virulence Factor Secretion by Yuki Yamanaka
DESCRIPTION:Please be informed of SPSS Meeting Seminar @ 9.30am on 28 March at Level 5 Seminar Room. \nPresenter 1: Xia Shumin\nTalk Title: The organization and regulation of the actin cortex in mouse embryonic stem cells \nPresenter 2: Yuki Yamanaka\nTalk Title: Control of Needle Length and Virulence Factor Secretion
URL:https://www.mbi.nus.edu.sg/event/mbi-spss-control-of-needle-length-and-virulence-factor-secretion-by-yuki-yamanaka/
LOCATION:MBI Seminar Room Lvl 5\, T-Lab\, Level 5\, 5A Engineering Drive 1\, Mechanobiology Institute\, National University of Singapore\, 117411\, Singapore
CATEGORIES:MBI Student & Postdoc Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Shanghai:20170330T160000
DTEND;TZID=Asia/Shanghai:20170330T170000
DTSTAMP:20260628T001256
CREATED:20170327T040018Z
LAST-MODIFIED:20170327T040018Z
UID:17746-1490889600-1490893200@www.mbi.nus.edu.sg
SUMMARY:MBI PhD Defense: Understanding Rho-A localized activation at the acto-myosin cortex by Leeba Ann CHACKO
DESCRIPTION:Understanding Rho-A localized activation at the acto-myosin cortex\nSpeaker          :   Leeba Ann CHACKO (Graduate Student\, MBI\, NUS)\nDate                :   30 Mar 2017\, Thursday\nTime                :   4pm\nVenue             :   MBI\, level 5 meeting rooms \nSupervisor(s)  :  Asst. Prof Ronen ZAIDEL-BAR \nAbstract: Actomyosin contractility is a highly conserved and regulated process that affects all the cells in our body and is responsible for various fundamental biological processes such as cell division\, cell migration\, endocytosis as well as force generation. It has been observed that some cells undergo pulsed contractility\, which involves the localized activation of the actomyosin network. Pulsed contractility is a phenomenon mostly observed in non-muscle cells and has shown to be responsible for tissue morphogenesis. However\, the mechanism by which cells undergo specialized local activation of actin and myosin during pulsed contractions is poorly understood. In order to address this question\, we use quantitative imaging techniques along with genetic perturbation experiments to understand the mechanism that leads to pulsed contractility using early C. elegans embryos. Rho-A activation is the first signal to drive localized pulsed contractions and this localized activation of Rho-A is independent of myosin activity however\, it is somewhat dependent on F-actin activity. \nIn order for Rho-A to be active in specific locations it needs to either be activated by distinct molecular players in the regions where Rho-A appears or Rho-A is inactivated by inhibitor molecules in regions where Rho-A does not appear. In order to test these hypotheses\, we looked at the plus end of microtubules specifically\, the microtubule plus end binding protein\, ebp-1 as the candidate for Rho-A localized activation in the cortex. On the other hand\, in order to test whether inhibitors are playing a role in hampering the appearance of Rho-A where Rho-A is not visualized at the cortex\, we used the transmembrane protein cadherin as a likely candidate. With the help of quantitative imaging and genetic perturbations\, we found that the microtubule end binding protein\, ebp-1 does not play a role in locally activating Rho-A. However\, it turns out that the cadherin protein\, Hmr-1 as well as the catenin proteins are present in regions where Rho-A is absent in the C. elegans early embryo and plays a role in inhibiting Rho-A expression at the cortex. Therefore based on these findings\, we propose that inhibitors of Rho-A dictate the specialized localization of Rho-A and Rho-A is maintained in the form of concentrated puncta at the cortex with the help of F-actin thus driving pulsed contractility and thereby producing various morphogenic outcomes. \nALL EXCEPT PANEL ARE EXCUSED FOR CLOSE DOOR EXAMINATION
URL:https://www.mbi.nus.edu.sg/event/mbi-phd-defense-understanding-rho-a-localized-activation-at-the-acto-myosin-cortex-by-leeba-ann-chacko/
LOCATION:MBI Seminar Room Lvl 5\, T-Lab\, Level 5\, 5A Engineering Drive 1\, Mechanobiology Institute\, National University of Singapore\, 117411\, Singapore
CATEGORIES:PhD Oral Defense
END:VEVENT
END:VCALENDAR