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X-WR-CALNAME:Mechanobiology Institute, National University of Singapore
X-ORIGINAL-URL:https://www.mbi.nus.edu.sg
X-WR-CALDESC:Events for Mechanobiology Institute, National University of Singapore
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DTSTART:20150101T000000
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BEGIN:VEVENT
DTSTART;TZID=UTC:20160517T160000
DTEND;TZID=UTC:20160517T163000
DTSTAMP:20260417T111230
CREATED:20160516T000013Z
LAST-MODIFIED:20160516T001748Z
UID:12871-1463500800-1463502600@www.mbi.nus.edu.sg
SUMMARY:MBI SPSS: Biophysical Model of Pattern Formation on the Cellular Cortex
DESCRIPTION:by Tatsuo Shibata \nFrom: RIKEN Quantitative Biology Center\nHosted by: Fumio Motegi & Sasha Bershadsky\nLocation: Level 5 T-Lab Building Seminar Room\nTime: 4pm – 5pm\nDate: 17th May 2016 \nThe plasma membrane is the central place that perceives and maintains signals from its surroundings\, and processes them to organize cellular behaviors. The phosphoinositide metabolism takes place on the plasma membrane and controls many cell biological processes. The distribution of phosphoinositide components can sometimes undergo spontaneous symmetry breaking and exhibit non-uniformity in space and time even in the absence of external asymmetries. The spatiotemporal non-uniform behaviors give rise to self-organization of excitability\, oscillation\, traveling waves and stationary spots.  Previous reports have suggested that kinases and phosphatases for phosphoinositide components play pivotal roles on the symmetry breaking. Such an intrinsic self-organization leads to the emergence of parameter that can be specified by external signals\, such as the migration direction controlled by the external chemical gradient. \n 
URL:https://www.mbi.nus.edu.sg/event/mbi-spss-biophysical-model-of-pattern-formation-on-the-cellular-cortex-and-large-collection-of-quantitative-data-on-spatiotemporal-dynamics-of-embryo-and-its-applications-to-data-driven-modeling-of-e/
LOCATION:MBI Seminar Room Lvl 5\, T-Lab\, Level 5\, 5A Engineering Drive 1\, Mechanobiology Institute\, National University of Singapore\, 117411\, Singapore
CATEGORIES:MBI Student & Postdoc Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20160517T163000
DTEND;TZID=UTC:20160517T170000
DTSTAMP:20260417T111230
CREATED:20160516T000955Z
LAST-MODIFIED:20160516T001723Z
UID:12875-1463502600-1463504400@www.mbi.nus.edu.sg
SUMMARY:MBI SPSS: Large Collection of Quantitative Data on Spatiotemporal Dynamics of Embryo and its Applications to Data-driven Modeling of Embryogenesis
DESCRIPTION:by Shuichi Onami \nFrom: RIKEN Quantitative Biology Center\nHosted by: Fumio Motegi & Sasha Bershadsky \nQuantitative data on spatiotemporal dynamics of embryo provide crucial information for understanding the mechanism of development. Combinations of live imaging and computational image-processing technologies have produced a large amount and a wide variety of quantitative dynamics data on embryogenesis. In this seminar\, I will introduce our large collection of quantitative data on nuclear division dynamics in early C. elegans embryos. These data were obtained by combining four-dimensional microscopy and computational image processing under gene perturbations of each of all essential embryonic genes. We developed a method to elucidate the sequence of phenotype expression by computing correlations between phenotypic characters. We also developed a method to infer genes involved in the phenotype expression network by computing outliers in the correlations. I would like to discuss how quantitative dynamics data provide new opportunities in biology. I would also like to introduce our SSBD database (http://ssbd.qbic.riken.jp) for storing and sharing quantitative biological dynamics data. This database is developed and maintained as a part of the Life Science Database Integration Project in Japan to sustainably store and share quantitative biological dynamics data that are created by the Japanese science community and beyond.
URL:https://www.mbi.nus.edu.sg/event/mbi-spss-large-collection-of-quantitative-data-on-spatiotemporal-dynamics-of-embryo-and-its-applications-to-data-driven-modeling-of-embryogenesis/
LOCATION:MBI Seminar Room Lvl 5\, T-Lab\, Level 5\, 5A Engineering Drive 1\, Mechanobiology Institute\, National University of Singapore\, 117411\, Singapore
CATEGORIES:MBI Student & Postdoc Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20160524T093000
DTEND;TZID=UTC:20160524T100000
DTSTAMP:20260417T111230
CREATED:20160517T174221Z
LAST-MODIFIED:20160517T174423Z
UID:12922-1464082200-1464084000@www.mbi.nus.edu.sg
SUMMARY:MBI SPSS: The effects of POPX2 phosphatase on cellular perception of topography and ciliation in static and migratory conditions
DESCRIPTION:Date: 24th May 2016\, Tuesday\nTime: 9.30am\nVenue: T-Lab Level 5 Seminar Room \nThe effects of POPX2 phosphatase on cellular perception of topography and ciliation in static and migratory conditions\nby Sharvari Sathe
URL:https://www.mbi.nus.edu.sg/event/mbi-spss-the-effects-of-popx2-phosphatase-on-cellular-perception-of-topography-and-ciliation-in-static-and-migratory-conditions/
LOCATION:MBI Seminar Room Lvl 5\, T-Lab\, Level 5\, 5A Engineering Drive 1\, Mechanobiology Institute\, National University of Singapore\, 117411\, Singapore
CATEGORIES:MBI Student & Postdoc Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20160524T100000
DTEND;TZID=UTC:20160524T103000
DTSTAMP:20260417T111230
CREATED:20160517T174354Z
LAST-MODIFIED:20160517T174354Z
UID:12923-1464084000-1464085800@www.mbi.nus.edu.sg
SUMMARY:MBI SPSS: Effects of RHAU helicase on G4 stability during ATPase cycle
DESCRIPTION:Effects of RHAU helicase on G4 stability during ATPase cycle\nby You Huijuan
URL:https://www.mbi.nus.edu.sg/event/mbi-spss-effects-of-rhau-helicase-on-g4-stability-during-atpase-cycle/
LOCATION:MBI Seminar Room Lvl 5\, T-Lab\, Level 5\, 5A Engineering Drive 1\, Mechanobiology Institute\, National University of Singapore\, 117411\, Singapore
CATEGORIES:MBI Student & Postdoc Seminar
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