BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Mechanobiology Institute, National University of Singapore - ECPv6.15.12.2//NONSGML v1.0//EN
CALSCALE:GREGORIAN
METHOD:PUBLISH
X-ORIGINAL-URL:https://www.mbi.nus.edu.sg
X-WR-CALDESC:Events for Mechanobiology Institute, National University of Singapore
REFRESH-INTERVAL;VALUE=DURATION:PT1H
X-Robots-Tag:noindex
X-PUBLISHED-TTL:PT1H
BEGIN:VTIMEZONE
TZID:Asia/Singapore
BEGIN:STANDARD
TZOFFSETFROM:+0800
TZOFFSETTO:+0800
TZNAME:+08
DTSTART:20170101T000000
END:STANDARD
END:VTIMEZONE
BEGIN:VEVENT
DTSTART;TZID=Asia/Singapore:20181120T093000
DTEND;TZID=Asia/Singapore:20181120T103000
DTSTAMP:20260417T131321
CREATED:20181113T063337Z
LAST-MODIFIED:20181113T063337Z
UID:25338-1542706200-1542709800@www.mbi.nus.edu.sg
SUMMARY:MBI SPSS: Force dependence of filopodia adhesion by Naila Alieva
DESCRIPTION:MBI Student and Postdoc Seminar Series (SPSS)\nTime: 9.30am-10.30am\nDate: Tuesday\,  20 November 2018\nVenue: Level 5 Seminar Room\, T-Lab \nForce dependence of filopodia adhesion\nBy Naila Alieva\, Facility Manager\, Bershadsky Group \n  \n* Please note this event is open to MBI researchers and invited guests only. Thank you *
URL:https://www.mbi.nus.edu.sg/event/mbi-spss-force-dependence-of-filopodia-adhesion-by-naila-alieva/
LOCATION:MBI Seminar Room Lvl 5\, T-Lab\, Level 5\, 5A Engineering Drive 1\, Mechanobiology Institute\, National University of Singapore\, 117411\, Singapore
CATEGORIES:MBI Seminar,MBI Student & Postdoc Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Singapore:20181123T093000
DTEND;TZID=Asia/Singapore:20181123T103000
DTSTAMP:20260417T131321
CREATED:20181120T045813Z
LAST-MODIFIED:20181120T045848Z
UID:25349-1542965400-1542969000@www.mbi.nus.edu.sg
SUMMARY:MBIw: Probing intracellular self-organization under geometric constraints using micro-compartments and micromanipulation by Ivo A Telley
DESCRIPTION:MBI Weekly Meeting Seminar\nTime: 9.30am-10.30am\nDate: Friday\, 23 November 2018\nVenue: Level 5 Seminar Room\, T-Lab \nProbing intracellular self-organization under geometric constraints using micro-compartments and micromanipulation\nBy Ivo A. Telley\, Instituto Gulbenkian de Ciência (IGC)\, Oeiras\, Portugal \n 
URL:https://www.mbi.nus.edu.sg/event/mbiw-probing-intracellular-self-organization-under-geometric-constraints-using-micro-compartments-and-micromanipulation-by-ivo-a-telley/
LOCATION:MBI Seminar Room Lvl 5\, T-Lab\, Level 5\, 5A Engineering Drive 1\, Mechanobiology Institute\, National University of Singapore\, 117411\, Singapore
CATEGORIES:MBI Seminar,MBI Weekly Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Singapore:20181127T150000
DTEND;TZID=Asia/Singapore:20181127T160000
DTSTAMP:20260417T131321
CREATED:20181112T050337Z
LAST-MODIFIED:20181112T050337Z
UID:25322-1543330800-1543334400@www.mbi.nus.edu.sg
SUMMARY:MBI PhD Oral Defense: Dissecting the role of topographical cues in endothelialization process by Azita Gorji
DESCRIPTION:MBI PhD Oral Defense\nTime: 3pm\nDate: Tuesday\, 27 November 2018\nVenue: NUS Faculty of Engineering\, E4-04-03 \nSupervisors: Prof Pakorn Kanchanawong (Main supervisor) \nDissecting the role of topographical cues in endothelialization process\nby Azita GORJI\, Kanchanawong Group \nA major challenge in the treatment of cardiovascular disease is graft failure due to late endothelialization of small synthetic vascular grafts.  Although several biochemical and mechanical strategies have been applied to promote endothelialization of the graft surfaces\, enhancement of implant endothelialization has been limited. The integrity of Endothelial Cells (ECs) monolayer is crucial for endothelialization\, but the understanding of the crosstalk between surface modification and cell-cell connectivity is still limited.  Toward a more effective approach to enhance endothelialization\, in this thesis a combined strategy making use of both topographical features and biochemical perturbations was investigated. The effect of micron-scale anisotropic topography on ECs behaviors is analyzed in conjunction with pharmacological perturbations of EC junctions regulators. We identified a protein tyrosine phosphatase\, PTP1B\, as a potent regulator of ECs junction stability. Our results showed that PTP1B inhibition synergized with grating topographies to modulate EC adherens junction’s rearrangement resulting in global EC monolayer sheet orientation\, connectivity and migration. Our data suggest utilizing grating topographies and PTP1B inhibitor together as a possible platform to enhance endothelialization of vascular grafts. \n  \n**Please note the examination following the seminar is closed-door** \n  \n 
URL:https://www.mbi.nus.edu.sg/event/mbi-phd-oral-defense-dissecting-the-role-of-topographical-cues-in-endothelialization-process-by-azita-gorji/
LOCATION:MBI Seminar Room Lvl 5\, T-Lab\, Level 5\, 5A Engineering Drive 1\, Mechanobiology Institute\, National University of Singapore\, 117411\, Singapore
CATEGORIES:MBI Seminar,PhD Oral Defense
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Singapore:20181129T140000
DTEND;TZID=Asia/Singapore:20181129T150000
DTSTAMP:20260417T131321
CREATED:20181127T012627Z
LAST-MODIFIED:20181127T013554Z
UID:25358-1543500000-1543503600@www.mbi.nus.edu.sg
SUMMARY:Computational microscopy of dynamic order across biological scales by Shalin Mehta
DESCRIPTION:MBI Seminar\nWe are pleased to inform you of the seminar by Dr. Shalin Mehta\, hosted by Prof. Pakorn Tony Kanchanawong\, entitled Computational microscopy of dynamic order across biological scales on 29 November 2018 (Thursday) @ 2.00pm at T-Lab Level 5 Seminar Rooms. \n 
URL:https://www.mbi.nus.edu.sg/event/computational-microscopy-of-dynamic-order-across-biological-scales-by-shalin-mehta/
LOCATION:MBI Seminar Room Lvl 5\, T-Lab\, Level 5\, 5A Engineering Drive 1\, Mechanobiology Institute\, National University of Singapore\, 117411\, Singapore
CATEGORIES:MBI Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Asia/Singapore:20181130T093000
DTEND;TZID=Asia/Singapore:20181130T103000
DTSTAMP:20260417T131321
CREATED:20181127T012339Z
LAST-MODIFIED:20181127T013701Z
UID:25355-1543570200-1543573800@www.mbi.nus.edu.sg
SUMMARY:MBIw: Engineering heterotypic cellular interactions for disease modeling and drug testing by Yi-Chin Toh
DESCRIPTION:MBI Seminar\nWe are pleased to inform you of the seminar by Prof Yi-Chin Toh\, hosted by Prof Virgile Viasnoff\, entitled Engineering heterotypic cellular interactions for disease modeling and drug testing on 30 November 2018 (Friday) @9.30am at T-Lab Level 5 Seminar Rooms. \n 
URL:https://www.mbi.nus.edu.sg/event/mbiw-engineering-heterotypic-cellular-interactions-for-disease-modeling-and-drug-testing-by-yi-chin-toh/
LOCATION:MBI Seminar Room Lvl 5\, T-Lab\, Level 5\, 5A Engineering Drive 1\, Mechanobiology Institute\, National University of Singapore\, 117411\, Singapore
CATEGORIES:MBI Seminar,MBI Weekly Seminar
END:VEVENT
END:VCALENDAR