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X-WR-CALNAME:Mechanobiology Institute, National University of Singapore
X-ORIGINAL-URL:https://www.mbi.nus.edu.sg
X-WR-CALDESC:Events for Mechanobiology Institute, National University of Singapore
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DTSTART:20150101T000000
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BEGIN:VEVENT
DTSTART;TZID=UTC:20160905T100000
DTEND;TZID=UTC:20160905T110000
DTSTAMP:20260429T173948
CREATED:20160815T191650Z
LAST-MODIFIED:20160815T191650Z
UID:14148-1473069600-1473073200@www.mbi.nus.edu.sg
SUMMARY:Targeting the architecture of the cancer cell: From basic cell biology to first-in-class therapeutics
DESCRIPTION:I am pleased to inform you on the seminar by Prof. Peter Gunning from University of New South Wales\, Australia\, titled “Targeting the architecture of the cancer cell: From basic cell biology to first-in-class therapeutics”. \nDate: 05 Sept 2016\, Mon\nTime: 10:00am\nVenue: Level 5 seminar room\, T-Lab\nHost: Prof Alexander Bershadsky \nProf Gunning’s Biodata\nProfessor Gunning completed his PhD at Monash University on gene expression in the nervous system and then spent 9 years at Stanford University working first on neuronal differentiation and then on the regulation of muscle gene expression. The latter project involved the cloning of the human contractile proteins which facilitated our cloning of the genes encoding the structural proteins of the skeleton of human cells. \nSince returning to Australia his research group has used these genes to study the assembly of the architecture of cells and tissues. They have discovered that a family of proteins called tropomyosins are used to specify the spatial and temporal properties of the cell skeleton. This has provided an entirely new model to account for the range of architectural structures found in cells and allows them to dissect these different structures using genetically modified mice and cells. Mouse models have allowed them to link specific types of structures with specific physiological processes such as cell/tissue growth\, glucose metabolism\, muscle contraction and neuronal morphogenesis. These models have also revealed the role of cell architecture in diseases as diverse as cancer and obesity. This knowledge has been used to develop new drugs with the potential to treat childhood cancer and other malignancies. \nProfessor Gunning has published over 140 research papers and recently edited the book “Tropomyosin”. He is on the Board of the NSW Cancer Institute and served as the Chair of the NSW Cancer Institute Cancer Research Advisory Committee for 6 years. Professor Gunning was the inaugural Chair of the Division of Research at The Children’s Hospital at Westmead\, Sydney\, and the Founding Chair of Bio-Link Pty Ltd. \nProf Gunning’s research\nHis research is focussed on diseases of childhood\, primarily cancer and muscle damage. Peter is best known for his discovery of one of the key principles underlying the architecture of all cells and its application to childhood cancer. He is also engaged in adult stem cell research to both limit the impact of chemotherapy on children with brain tumours and to enhance the rebuilding of diseased muscles using muscle stem cells. \nAll are welcome.
URL:https://www.mbi.nus.edu.sg/event/targeting-the-architecture-of-the-cancer-cell-from-basic-cell-biology-to-first-in-class-therapeutics/
LOCATION:MBI Seminar Room Lvl 5\, T-Lab\, Level 5\, 5A Engineering Drive 1\, Mechanobiology Institute\, National University of Singapore\, 117411\, Singapore
CATEGORIES:MBI Seminar
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BEGIN:VEVENT
DTSTART;TZID=UTC:20160914T140000
DTEND;TZID=UTC:20160914T150000
DTSTAMP:20260429T173948
CREATED:20160907T174425Z
LAST-MODIFIED:20160907T174425Z
UID:14203-1473861600-1473865200@www.mbi.nus.edu.sg
SUMMARY:Collective migration of epithelial cells induced by direction-dependent contraction forces on cell boundaries by Katsuhiko Sato
DESCRIPTION:
URL:https://www.mbi.nus.edu.sg/event/collective-migration-of-epithelial-cells-induced-by-direction-dependent-contraction-forces-on-cell-boundaries-by-katsuhiko-sato/
LOCATION:MBI Seminar Room Lvl 5\, T-Lab\, Level 5\, 5A Engineering Drive 1\, Mechanobiology Institute\, National University of Singapore\, 117411\, Singapore
CATEGORIES:MBI Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20160926T170000
DTEND;TZID=UTC:20160926T180000
DTSTAMP:20260429T173948
CREATED:20160912T174942Z
LAST-MODIFIED:20160914T184851Z
UID:14219-1474909200-1474912800@www.mbi.nus.edu.sg
SUMMARY:Mechanical and Dynamic Properties of Nonmuscle Myosim-2 Filaments by James Sellers
DESCRIPTION:
URL:https://www.mbi.nus.edu.sg/event/mbi-seminar-mechanical-and-dynamic-properties-of-nonmuscle-myosim-2-filaments/
LOCATION:MBI Seminar Room Lvl 5\, T-Lab\, Level 5\, 5A Engineering Drive 1\, Mechanobiology Institute\, National University of Singapore\, 117411\, Singapore
CATEGORIES:MBI Seminar
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