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DTSTART;VALUE=DATE:20151016
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SUMMARY:MBI WIS: 2015 BIOS: Biological Symposium by the MBI WIS Initiative
DESCRIPTION:Bios2015: Biological Symposium\nby the MBI WIS Initiative\n16 October\, 2015\nLevel 5\, T-Lab\, Mechanobiology Institute\, National University of Singapore \nDownload BIOS2015 poster \nA symposium brought to you by the Mechanobiology Institute (MBI) Women in Science (WIS) Initiative\, BIOS2015 aims to promote biological sciences by bringing together scientists from diverse realms of life sciences research in Singapore. \nThis one-of-a-kind symposium will show case work from top research institutes in Singapore\, including NUS\, D3\, IMB\, NNS\, NTU\, NNI\, DUKE NUS and TLL\, spanning research in basic sciences\, translational sciences and drug discovery. \nWith a specific focus on junior careers in academia for its first meeting planned on 16th October 2015\, BIOS 2015 will also have a panel discussion towards the end of the symposium. \nKeynote Speaker\nKatharina Gaus\, University of New South Wales (UNSW)\nTalk: Molecular insights into the regulation of T cell signalling\nDr Katharina Gaus is head of the Cellular Membrane Biology Laboratory at the University of New South Wales. The main aim of her research has been to gain a mechanistic understanding of the organisation of the plasma membrane within cells. She has pioneered fluorescence microscopy approaches to examine and quantify cell signalling on a single molecule level (super-resolution microscopy) in living cells. Her work aims to link membrane organisation to cell signalling by implementing single-molecule imaging techniques and using novel cell-activating surfaces. \nPanel discussion to follow the keynote speaker. Short talks will be selected from submitted abstracts. \nSpeakers\nYunn Hwen Gan\, Yong Loo Lin School of Medicine\, NUS\nTalk: Unraveling the mystery of an endemic bacterial pathogen which also happens to be a bioterrorism agent\nAssoc Prof Gan’s research focuses on the interaction of Burkholderia pseudomallei with the host innate immune response\, genetic regulation of virulence in Burkholderia pseudomallei\, susceptibility factors in Type 2 diabetes to bacterial infections\, and bacterial sensing of host environment and Type III/Type VI bacterial secretion systems. \nSheemei Lok\, Emerging Infectious Diseases Program Duke-NUS\nTalk: CryoEM structure shows antibody neutralize dengue virusserotype 2 by locking E protein dimers\nAssistant Professor Lok is one of the recipients for the prestigious National Research Foundation fellowship. Dengue Virus (DENV) infects approximately 100 million people each year. Increased travel\, together with global climate change will result in further geographical expansion of the territory of the dengue mosquito vector\, Aedes aegypti. There is an urgent need to develop safe and effective dengue therapeutics and vaccine. \nMary B Chan-Park\, Nanyang Technological University (NTU)\nTalk: Selective Antimicrobial Polysaccharides For Diverse Applications\nProf Chan-Park’s research includes: polymer applications in biotechnology and nanotechnology\, antimicrobial polymers and hydrogels\, carbon nanotubes and graphene dispersion and sorting and printed electronics – surface patterning and modification. \nHu Xian\, MBI-NUS\nTalk: How does the Stretch Cycles of Talin in Mature Adhesions Recruit Vinculin – A Time Resolved Single Molecule Analysis \nReshma Taneja\, Yong Loo Lin School of Medicine NUS\nTalk: Unravelling epigenetic changes in skeletal myopathies\nThe long-term goal of our research program is to understand how basic helix-loop-helix (bHLH) family of transcription factors regulate cellular growth\, differentiation and apoptosis. Our lab has been interested in understanding the function and regulation of the bHLH factors Stra13/Dec1 and Sharp-1/Dec2 in the differentiation and regeneration of skeletal muscle\, as well as their potential roles in tumorigenesis. \nCarol Tang\, National Neuroscience Institute (NNI)\nTalk: Targeting Brain Tumors: Improving lives through Precision Medicine\nOur laboratory first started in June 2005 with a focus on the establishment of patient-derived glioma-propagating cells (GPCs) (Chong et al\, Stem Cells\, 2009). These stem-like cells exhibit many of the hallmarks of the primary tumor: stemness/ multipotentiality markers\, karyotype and transcriptomic profile. Importantly\, we and others showed that orthotopic xenografts established from GPCs recapitulate the pathophysiology of the patient’s original tumor. \nZhang Dan\, Temasek Lifesciences Laboratory (TLL)\nTalk: The cortical ER regulates actomyosin ring assembly through ER-PM contacts\nDr Zhang specializes in the study of membrane-bound organelles which establish multiple membrane contact sites (MCSs) through which they communicate and coordinate their functions. The broad goal of our lab is to elucidate the nature and functions of endomembrane contacts\, and to integrate their roles into a general framework of cell physiology\, using the fission yeastSchizosaccharomyces pombe as the main model organism. \nBee Luan\, MBI-NUS\nTalk: Short-term expansion of breast circulating cancer cells predicts response to Anti-cancer therapy \nPriyanka Balaganapathy\, NUS\nTalk: The role of Notch in p53 mediated neuronal cell death in cerebral ischemia \nBirgit Lane\, A*Star Institute of Medical Biology (IMB)\nTalk: Understanding keratin function through studying rare diseases\nProf Lane is known internationally for her work on keratins and has a long-standing interest in the function of the keratin cytoskeleton in epithelia and its importance in disease. She has made pioneering contributions to the use of monoclonal antibodies to keratins in diagnostic pathology and cell biology\, and to the recognition of keratin mutations as causing inherited skin fragility disorders. \n\n \nDownload program (PDF) \n\nVeronica Diermayr\, A*Star D3\nTalk: Moving forward – Singapore’s successes in oncology drug development\nDr Diermayr has gained a wide area of expertise in preclinical and early clinical development while in charge of the animal pharmacology group as well as the biomarker group\, working on S*BIO’s portfolio of small molecules\, developing and applying biomarker strategies during Phase I/II oncology trials. She has gained further insights at D3 (A*Star) on the development of biologics and the operational aspects of early clinical trials. Her continued focus of interest is oncology drug development as well as the development of biomarkers for targeted therapeutics. \nLee Wei Lin\, IMCB\nTalk: Yersinia effector YopO uses actin as bait to phosphorylate proteins that regulate actin polymerization \nCharlotte Guetta\, MBI-NUS\nTalk: Protrusive Waves Guide 3D Cell Migration Along Nanofibers \nJolene Tan\, AWARE\nJolene Tan is the Programmes and Communications Senior Manager for the Association of Women for Action and Research (AWARE)\, an organization in Singapore that works to support\, educate and advocate women’s civil and legal rights. \n Program\n16 October\, 2015\nLevel 5\, T-Lab\, Mechanobiology Institute\, National University of Singapore \nDownload full program (PDF) \n\n\n\n9:00am\nWelcome address: Linda Kenney\n\n\n\nSession 1: Microorganisms\nSession Chair: Mrinal Shah\n\n\n9:00am to\n9:30am\nYunn Hwen Gan\nUnraveling the mystery of an endemic bacterial pathogen which also happens to be a bioterrorism agent\n\n\n9:30am to 10:00am\nSheemei Lok\nCryoEM structure shows antibody neutralize dengue virusserotype 2 by locking E protein dimers\n\n\n10:00am to 10:30am\nMary B Chan-Park\nSelective antimicrobial polysaccharides for diverse applications\n\n\n10:30am to 10:45am\nHu Xian\nHow does the stretch cycles of talin in mature adhesions recruit vinculin- a time resolved single molecule analysis\n\n\n10:45am to 11:00am\nCoffee Break\n\n\n\nSession II: Cell Signaling in Disease\nSession chair: Pascale Monzo\n\n\n11:00am to 11:30am\nReshma Taneja\nUnravelling epigenetic changes in skeletal myopathies\n\n\n11:30am to 12:00am\nCarol Tang\nTargeting brain tumors: improving lives through precision medicine\n\n\n12:00am to 12:30pm\nZhang Dan\nThe cortical ER regulates actomyosin ring assembly through ER-PM contacts\n\n\n12:30pm to 12:45pm\nBee Luan\nShort-term expansion of breast circulating cancer cells predicts response to Anti-cancer therapy\n\n\n12:45pm to 1:00pm\nPriyanka Balaganapathy\nThe role of Notch in p53 mediated neuronal cell death in cerebral ischemia\n\n\n1:00pm to 2:00pm\n Lunch\n\n\n\nSession III: Cytoskeleton\, Disease and Drugs\nSession chair: Rishita Changede\n\n\n2:00pm\nto 2:30pm\nBirgit Lane\nUnderstanding keratin function through studying rare diseases\n\n\n2:30pm\nto 3:00pm\nVeronica Diermayr\nMoving forward- Singapore’s successes in oncology drug development\n\n\n3:00pm\nto 3:15pm\nLee Wei Lin\nYersinia effector YopO uses actin as bait to phosphorylate proteins that regulate actin polymerization\n\n\n3:15pm\nto 3:30pm\nCharlotte Guetta\nProtrusive waves guide 3D cell migration along nanofibers\n\n\n3:30pm\nto 4:00pm\nCoffee Break\n\n\n\n Keynote\n\n\n\n4:00pm\nto 5:00pm\nKatharina Gaus\nMolecular insights into the regulation of T cell signalling\n\n\n5:00pm\nto 6:00pm\nPanel discussion\nPanelists: Katharina Gaus\, Mary B Chan-Park\, Veronica Diermayr\,Reshma Taneja\, Zhang Dan\, Jolene Tan (AWARE)\n\n\n6:00pm\nConcluding remarks: Stuti Desai\n\n\n\nTo follow: Happy hour at Lvl 10\, MBI\, T-Lab\n\n\n\n Sponsors\n \n  \n 
URL:https://www.mbi.nus.edu.sg/event/mbi-wis-2015-bios-biological-symposium-by-the-mbi-wis-initiative/
LOCATION:MBI Seminar Room Lvl 5\, T-Lab\, Level 5\, 5A Engineering Drive 1\, Mechanobiology Institute\, National University of Singapore\, 117411\, Singapore
CATEGORIES:Conference,MBI WIS
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